Evidence that Brain-Reactive Autoantibodies Contribute to Chronic Neuronal Internalization of Exogenous Amyloid-β1-42 and Key Cell Surface Proteins During Alzheimer’s Disease Pathogenesis

Differential Effects of Alzheimer’s Disease Aβ40 and 42 on Endocytosis and Intraneuronal Trafficking

(2018) Rajesh S. Omtri et al.   NEUROSCIENCE

Brain-Reactive Autoantibodies Prevalent in Human Sera Increase Intraneuronal Amyloid-β1-42 Deposition

(2018) Robert G. Nagele et al.   JOURNAL OF ALZHEIMERS DISEASE

Diabetes and Hypercholesterolemia Increase Blood-Brain Barrier Permeability and Brain Amyloid Deposition: Beneficial Effects of the LpPLA2 Inhibitor Darapladib

(2018) Nimish K. Acharya et al.   JOURNAL OF ALZHEIMERS DISEASE

Autoantibodies as diagnostic biomarkers for the detection and subtyping of multiple sclerosis

(2017) Cassandra DeMarshall et al.   JOURNAL OF NEUROIMMUNOLOGY

Endocytic uptake of monomeric amyloid-β peptides is clathrin- and dynamin-independent and results in selective accumulation of Aβ(1–42) compared to Aβ(1–40)

(2017) Emelie Wesén et al.   Scientific Reports

Perforin Promotes Amyloid Beta Internalisation in Neurons

(2016) Erica Lana et al.   MOLECULAR NEUROBIOLOGY

Neuronal amyloid-β accumulation within cholinergic basal forebrain in ageing and Alzheimer’s disease

(2015) Alaina Baker-Nigh et al.   BRAIN

Potential utility of autoantibodies as blood-based biomarkers for early detection and diagnosis of Parkinson’s disease

(2015) Cassandra A. DeMarshall et al.   IMMUNOLOGY LETTERS

LC3 overexpression reduces Aβ neurotoxicity through increasing α7nAchR expression and autophagic activity in neurons and mice

(2015) Shih-Ya Hung et al.   NEUROPHARMACOLOGY

Histamine Induces Alzheimer’s Disease-Like Blood Brain Barrier Breach and Local Cellular Responses in Mouse Brain Organotypic Cultures

(2015) Jonathan C. Sedeyn et al.   Biomed Research International

Seroprevalence of autoantibodies against brain antigens in health and disease

(2014) Liane Dahm et al.   ANNALS OF NEUROLOGY

Acute mechanisms underlying antibody effects in anti-N-methyl-D-aspartate receptor encephalitis

(2014) Emilia H. Moscato et al.   ANNALS OF NEUROLOGY

Developing novel blood-based biomarkers for Alzheimer's disease

(2013) Heather M. Snyder et al.   Alzheimers & Dementia

α7 Nicotinic Receptor Agonist Enhances Cognition in Aged 3xTg-AD Mice with Robust Plaques and Tangles

(2013) Rodrigo Medeiros et al.   AMERICAN JOURNAL OF PATHOLOGY

Natural IgG Autoantibodies Are Abundant and Ubiquitous in Human Sera, and Their Number Is Influenced By Age, Gender, and Disease

(2013) Eric P. Nagele et al.   PLoS One

Hypercholesterolemia accelerates intraneuronal accumulation of Aβ oligomers resulting in memory impairment in Alzheimer's disease model mice

(2012) Tomohiro Umeda et al.   LIFE SCIENCES

Diagnosis of Parkinson's Disease Based on Disease-Specific Autoantibody Profiles in Human Sera

(2012) Min Han et al.   PLoS One

2011 Alzheimer’s disease facts and figures

(2011)   Alzheimers & Dementia

Toward defining the preclinical stages of Alzheimer’s disease: Recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease

(2011) Reisa A. Sperling et al.   Alzheimers & Dementia

Quantitative proteomics analysis of phosphorylated proteins in the hippocampus of Alzheimer's disease subjects

(2011) Fabio Di Domenico et al.   Journal of Proteomics

Diagnosis of Alzheimer's Disease Based on Disease-Specific Autoantibody Profiles in Human Sera

(2011) Eric Nagele et al.   PLoS One

Brain-reactive autoantibodies are nearly ubiquitous in human sera and may be linked to pathology in the context of blood–brain barrier breakdown

(2010) Eli C. Levin et al.   BRAIN RESEARCH

Mechanism of amyloid plaque formation suggests an intracellular basis of A  pathogenicity

(2010) R. P. Friedrich et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Rapid and Direct Transport of Cell Surface APP to the Lysosome defines a novel selective pathway

(2010) Angela Lorenzen et al.   Molecular Brain

Dissociating  -Amyloid from  7 Nicotinic Acetylcholine Receptor by a Novel Therapeutic Agent, S 24795, Normalizes  7 Nicotinic Acetylcholine and NMDA Receptor Function in Alzheimer's Disease Brain

(2009) H.-Y. Wang et al.   JOURNAL OF NEUROSCIENCE

Amyloid seeds formed by cellular uptake, concentration, and aggregation of the amyloid-beta peptide

(2009) X. Hu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA