Chronic Treatment with 50 mg/kg Cannabidiol Improves Cognition and Moderately Reduces Aβ42 Levels in 12-Month-Old Male AβPPswe/PS1ΔE9 Transgenic Mice

Cannabidiol Induces Rapid and Sustained Antidepressant-Like Effects Through Increased BDNF Signaling and Synaptogenesis in the Prefrontal Cortex

(2018) Amanda J. Sales et al.   MOLECULAR NEUROBIOLOGY

The effects of cannabidiol (CBD) on cognition and symptoms in outpatients with chronic schizophrenia a randomized placebo controlled trial

(2018) Douglas L. Boggs et al.   PSYCHOPHARMACOLOGY

Natural Cannabinoids Improve Dopamine Neurotransmission and Tau and Amyloid Pathology in a Mouse Model of Tauopathy

(2018) Maria J. Casarejos et al.   JOURNAL OF ALZHEIMERS DISEASE

Cannabis-Based Medicine Reduces Multiple Pathological Processes in AβPP/PS1 Mice

(2018) Ester Aso et al.   JOURNAL OF ALZHEIMERS DISEASE

Long-Term Cannabidiol Treatment Prevents the Development of Social Recognition Memory Deficits in Alzheimer's Disease Transgenic Mice

(2018) David Cheng et al.   JOURNAL OF ALZHEIMERS DISEASE

The neural basis of reversal learning: An updated perspective

(2017) A. Izquierdo et al.   NEUROSCIENCE

In vivo Evidence for Therapeutic Properties of Cannabidiol (CBD) for Alzheimer's Disease

(2017) Georgia Watt et al.   Frontiers in Pharmacology

2016 Alzheimer's disease facts and figures

(2016)   Alzheimers & Dementia

Delineating the Efficacy of a Cannabis-Based Medicine at Advanced Stages of Dementia in a Murine Model

(2016) Ester Aso et al.   JOURNAL OF ALZHEIMERS DISEASE

Brain-derived neurotrophic factor and its clinical implications

(2015) Siresha Bathina et al.   Archives of Medical Science

Cytokine-producing microglia have an altered beta-amyloid load in aged APP/PS1 Tg mice

(2015) Alicia A. Babcock et al.   BRAIN BEHAVIOR AND IMMUNITY

Cannabinoids in late-onset Alzheimer's disease

(2015) AIA Ahmed et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Electroacupuncture decreases cognitive impairment and promotes neurogenesis in the APP/PS1 transgenic mice

(2014) Xuying Li et al.   BMC Complementary and Alternative Medicine

Chronic cannabidiol treatment improves social and object recognition in double transgenic APPswe/PS1∆E9 mice

(2014) David Cheng et al.   PSYCHOPHARMACOLOGY

Novel behavioural characteristics of the APPSwe/PS1ΔE9 transgenic mouse model of Alzheimer's disease

(2013) David Cheng et al.   BEHAVIOURAL BRAIN RESEARCH

Novel behavioural characteristics of female APPSwe/PS1ΔE9 double transgenic mice

(2013) David Cheng et al.   BEHAVIOURAL BRAIN RESEARCH

Cannabidiol Promotes Amyloid Precursor Protein Ubiquitination and Reduction of Beta Amyloid Expression in SHSY5YAPP+Cells Through PPARγ Involvement

(2013) Caterina Scuderi et al.   PHYTOTHERAPY RESEARCH

Microglia and Inflammation in Alzheimers Disease

(2012) Shweta Mandrekar-Colucci et al.   CNS & Neurological Disorders-Drug Targets

Genetic insights in Alzheimer's disease

(2012) Karolien Bettens et al.   LANCET NEUROLOGY

Soluble Aβ levels correlate with cognitive deficits in the 12-month-old APPswe/PS1dE9 mouse model of Alzheimer's disease

(2011) Wei Zhang et al.   BEHAVIOURAL BRAIN RESEARCH

Spatial and reversal learning in the Morris water maze are largely resistant to six hours of REM sleep deprivation following training

(2011) C. M. Walsh et al.   LEARNING & MEMORY

Cannabidiol and Other Cannabinoids Reduce Microglial Activation In Vitro and In Vivo: Relevance to Alzheimer's Disease

(2011) A. M. Martin-Moreno et al.   MOLECULAR PHARMACOLOGY

Cannabidiol Reduces Aβ-Induced Neuroinflammation and Promotes Hippocampal Neurogenesis through PPARγ Involvement

(2011) Giuseppe Esposito et al.   PLoS One

Evaluating spatial memory function in mice: A within-subjects comparison between the water maze test and its adaptation to dry land

(2010) L. Llano Lopez et al.   BEHAVIOURAL BRAIN RESEARCH

Enhancement of Spatial Reversal Learning by 5-HT2C Receptor Antagonism Is Neuroanatomically Specific

(2010) V. Boulougouris et al.   JOURNAL OF NEUROSCIENCE

The safety profile of ACI-24, an oligo-specific amyloid beta vaccine, demonstrated decrease of large microbleedings in brain of aged Alzheimer's disease mouse model

(2009) Maria Pihlgren et al.   Alzheimers & Dementia

Modulation of Microglial Innate Immunity in Alzheimers Disease by Activation of Peroxisome Proliferator-activated Receptor Gamma

(2009) Feng-Shiun Shie et al.   CURRENT MEDICINAL CHEMISTRY

Decreased Brain-Derived Neurotrophic Factor Depends on Amyloid Aggregation State in Transgenic Mouse Models of Alzheimer's Disease

(2009) S. Peng et al.   JOURNAL OF NEUROSCIENCE

Anti-depressant natural flavonols modulate BDNF and beta amyloid in neurons and hippocampus of double TgAD mice

(2009) Yan Hou et al.   NEUROPHARMACOLOGY

Neuroanatomical correlates of neuropsychiatric symptoms in Alzheimer's disease

(2008) P. D. Bruen et al.   BRAIN

Animal models of Alzheimer's disease and frontotemporal dementia

(2008) Jürgen Götz et al.   NATURE REVIEWS NEUROSCIENCE

PK11195 labels activated microglia in Alzheimer's disease and in vivo in a mouse model using PET

(2008) Sriram Venneti et al.   NEUROBIOLOGY OF AGING

PPARγ agonists as therapeutics for the treatment of Alzheimer’s disease

(2008) Gary Landreth et al.   Neurotherapeutics

Altered neuronal gene expression in brain regions differentially affected by Alzheimer's disease: a reference data set

(2008) Winnie S. Liang et al.   PHYSIOLOGICAL GENOMICS

Cannabidiol in medicine: a review of its therapeutic potential in CNS disorders

(2008) Caterina Scuderi et al.   PHYTOTHERAPY RESEARCH

GABAA Receptor-Mediated Acceleration of Aging-Associated Memory Decline in APP/PS1 Mice and Its Pharmacological Treatment by Picrotoxin

(2008) Yuji Yoshiike et al.   PLoS One

Cannabidiol in vivo blunts β-amyloid induced neuroinflammation by suppressing IL-1β and iNOS expression

(2007) G Esposito et al.   BRITISH JOURNAL OF PHARMACOLOGY