Article
Cardiac & Cardiovascular Systems
Jonas Persson, Jacinth Yan, Oskar Angeras, Dimitrios Venetsanos, Anders Jeppsson, Iwar Sjogren, Rikard Linder, David Erlinge, Torbjorn Ivert, Elmir Omerovic
Summary: This observational study aimed to analyze outcomes after coronary artery bypass grafting (CABG) or percutaneous coronary intervention (PCI) in patients with unprotected left main coronary artery (LMCA) disease. The study found that CABG was associated with lower mortality and fewer major adverse cardiovascular and cerebrovascular events (MACCE) compared to PCI in LMCA disease patients.
EUROPEAN HEART JOURNAL
(2023)
Review
Cardiac & Cardiovascular Systems
Laura J. Davidson, Joseph C. Cleveland, Frederick G. Welt, Saif Anwaruddin, Robert O. Bonow, Michael S. Firstenberg, Mario F. Gaudino, Bernard J. Gersh, Kendra J. Grubb, Ajay J. Kirtane, Jacqueline E. Tamis-Holland, Alexander G. Truesdell, Stephan Windecker, Roza A. Taha, Chris Malaisrie
Summary: The treatment of left main coronary artery disease requires complex decision-making. This article proposes a practical approach to treatment, including medical therapy, percutaneous coronary intervention, and coronary artery bypass grafting. It emphasizes the importance of shared decision-making that meets the needs and preferences of individual patients.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
(2022)
Article
Cardiac & Cardiovascular Systems
Derrick Y. Tam, Jiming Fang, Rodolfo V. Rocha, Sunil V. Rao, Vladimir Dzavik, Jennifer Lawton, Peter C. Austin, Mario Gaudino, Stephen E. Fremes, Douglas S. Lee
Summary: This study compared the long-term clinical outcomes of percutaneous coronary intervention (PCI) and coronary artery bypass grafting (CABG) in patients with left main coronary disease. The results showed that CABG had better survival rates and freedom from major adverse cardiac and cerebrovascular events, but there was no difference in early mortality.
JACC-CARDIOVASCULAR INTERVENTIONS
(2023)
Article
Medicine, General & Internal
Marc S. Sabatine, Brian A. Bergmark, Sabina A. Murphy, Patrick T. O'Gara, Peter K. Smith, Patrick W. Serruys, A. Pieter Kappetein, Seung-Jung Park, Duk-Woo Park, Evald H. Christiansen, Niels R. Holm, Per H. Nielsen, Gregg W. Stone, Joseph F. Sabik, Eugene Braunwald
Summary: A comparison of long-term outcomes between PCI with drug-eluting stents and CABG in patients with left main coronary artery disease showed no significant difference in 5-year all-cause mortality. However, differences were observed in rates of myocardial infarction, stroke, and repeat revascularisation, with higher risks associated with PCI. A Bayesian approach suggested a slight advantage favoring CABG in terms of mortality.
Review
Medicine, General & Internal
Emil Julian Dabrowski, Marcin Kozuch, Slawomir Dobrzycki
Summary: This paper provides a comprehensive review of state-of-the-art diagnostic and treatment methods of left main coronary artery disease, with a focus on percutaneous methods.
JOURNAL OF CLINICAL MEDICINE
(2022)
Review
Cardiac & Cardiovascular Systems
Alistair Royse, Justin Ren, Colin Royse, David H. Tian, Stephen Fremes, Mario Gaudino, Umberto Benedetto, Y. Joseph Woo, Andrew B. Goldstone, Piroze Davierwala, Michael Borger, Michael Vallely, Christopher M. Reid, Rodolfo Rocha, David Glineur, Juan Grau, Richard Shaw, Hugh Paterson, Doa El-Ansary, Stuart Boggett, Nilesh Srivastav, Zulfayandi Pawanis, David Canty, Rinaldo Bellomo
Summary: The study suggests that avoiding the use of saphenous vein grafts in total arterial revascularization (TAR) surgery can reduce patients' late survival rate and has a positive impact on reducing all-cause mortality.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
(2022)
Article
Cardiac & Cardiovascular Systems
Frederic Bouisset, Flavio Ribichini, Vincent Bataille, Krzysztof Reczuch, Thibault Lhermusier, Slawomir Dobrzycki, Markus Meyer-Gessner, Erwan Bressollette, Wojciech Zajdel, Benjamin Faurie, Nikolaos Mezilis, Jorge Palazuelos, Beatriz Vaquerizo, Miroslaw Ferenc, Guillaume Cayla, Emanuele Barbato, Didier Carrie
Summary: Data on rotational atherectomy percutaneous coronary intervention (RA PCI) angioplasty in the left main (LM) coronary artery are scarce and mostly outdated. This study found that RA PCI is an efficient option for treating calcified LM lesions, providing acceptable clinical outcomes and comparable results.
AMERICAN JOURNAL OF CARDIOLOGY
(2023)
Article
Physiology
Amin Daoulah, Rasha Taha Baqais, Alwaleed Aljohar, Abdulkarim Alhassoun, Ahmad S. Hersi, Wael Almahmeed, Nooraldaem Yousif, Abdulaziz Alasmari, Mohammed Alshehri, Fakhreldein Eltaieb, Badr Alzahrani, Ahmed Elmahrouk, Amr A. Arafat, Ahmed Jamjoom, Khalid Z. Alshali, Reda Abuelatta, Waleed A. Ahmed, Abdulrahman H. Alqahtani, Turki Al Garni, Shahrukh Hashmani, Ziad Dahdouh, Wael Refaat, Hameedullah M. Kazim, Mohamed Ajaz Ghani, Haitham Amin, Niranjan Hiremath, Youssef Elmahrouk, Ehab Selim, Jairam Aithal, Mohammed A. Qutub, Mohamed N. Alama, Ahmed M. Ibrahim, Abdelmaksoud Elganady, Abdulwali Abohasan, Farhan M. Asrar, Tarek Farghali, Maryam Jameel Naser, Taher Hassan, Mohammed Balghith, Adnan Fathey Hussien, Ibrahim A. M. Abdulhabeeb, Osama Ahmad, Mohamed Ramadan, Ahmed A. Ghonim, Abeer M. Shawky, Husam A. Noor, Ejazul Haq, Abdulrahman M. Alqahtani, Faisal Al Samadi, Seraj Abualnaja, Mushira Khan, Sameer Alhamid, Amir Lotfi
Summary: This study compared the outcomes of PCI and CABG in patients with impaired and normal renal function. The results showed that PCI had a lower risk of in-hospital MACCE in patients with impaired renal function, but there were no significant differences in follow-up MACCE between PCI and CABG.
KIDNEY & BLOOD PRESSURE RESEARCH
(2023)
Article
Cardiac & Cardiovascular Systems
Joshua Michael Rosenblum, Jose Binongo, Jane Wei, Yuan Liu, Bradley G. Leshnower, Edward P. Chen, Jeffrey S. Miller, Steven K. Macheers, Omar M. Lattouf, Robert A. Guyton, Vinod H. Thourani, Michael E. Halkos, William Brent Keeling
Summary: This study demonstrates that multiple arterial grafts provide a modest survival benefit over single-arterial grafting in mid-term outcomes after coronary artery bypass surgery. Surgeons may prefer multiple arterial grafting even in cases of incomplete revascularization, as it offers a protective effect on survival.
JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY
(2021)
Article
Cardiac & Cardiovascular Systems
Ayman Elbadawi, Mohammed Elzeneini, Islam Y. Elgendy, Michael Megaly, Mohamed Omer, Ernesto Jimenez, Ravi K. Ghanta, Emmanouil S. Brilakis, Hani Jneid
Summary: This study used a nationwide database to analyze the trends and outcomes of isolated coronary artery bypass grafting after ST-elevation myocardial infarction. The results showed a decline in the use of this procedure, but no change in in-hospital mortality. A recent cohort study found that performing the grafting on day 2 had similar in-hospital mortality compared with day 3 or more, but lower rates of complications and shorter hospital stays.
JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY
(2023)
Article
Cardiac & Cardiovascular Systems
Vincenzo Acerbo, Arturo Cesaro, Gianmaria Scherillo, Giovanni Signore, Francesco Paolo Rotolo, Gianantonio De Michele, Francesco Scialla, Giuseppe Raucci, Domenico Panico, Fabio Fimiani, Elisabetta Moscarella, Felice Gragnano, Paolo Calabro
Summary: Coronary artery disease (CAD) is the most common cause of heart failure with reduced ejection fraction (HFrEF). Advances in medical therapy have improved prognosis, but the effectiveness of surgical or percutaneous revascularization strategies is still debated.
HEART FAILURE REVIEWS
(2023)
Letter
Medicine, General & Internal
Eric Van Belle, Manesh Patel, Justin Davies
Summary: The FAME 3 trial showed that PCI did not meet noninferiority criteria compared to CABG in patients with three-vessel coronary artery disease. While preprocedural FFR-iFR measurement is beneficial in identifying vessels that benefit from revascularization, stent selection in the PCI group was based on angiography visual assessment.
NEW ENGLAND JOURNAL OF MEDICINE
(2022)
Article
Cardiac & Cardiovascular Systems
Max W. Maffey, Luiz F. Ybarra
Summary: Coronary artery bypass grafting (CABG) remains the mainstay of therapy in significant left main (LM) disease. Recent studies suggest that percutaneous coronary intervention (PCI) is a reasonable alternative with comparable clinical outcomes in select patients. Technical considerations must be made to optimize outcomes after PCI.
CURRENT TREATMENT OPTIONS IN CARDIOVASCULAR MEDICINE
(2023)
Article
Cardiac & Cardiovascular Systems
L. Poelzl, M. Thielmann, S. Cymorek, F. Naegele, J. Hirsch, M. Graber, N. Sappler, J. Eder, S. Staggl, F. Theurl, H. Abfalterer, S. J. Reinstadler, J. Holfeld, A. Griesmacher, H. Ulmer, M. Grimm, A. Bauer, E. Ruttmann-Ulmer, A. Ruhparwar, N. Bonaros, C. Gollmann-Tepekoeylue
Summary: This study analyzed the incidence and prognosis of perioperative myocardial infarction (pMI) after coronary artery bypass graft surgery using different definitions. The study found significant differences in the occurrence of pMI depending on the definition used, and the 4th Universal Definition of Myocardial Infarction and Academic Research Consortium criteria were strong independent predictors of all-cause mortality. In addition, new electrocardiographic abnormalities, regional wall motion abnormalities, or coronary angiography detected signs of ischemia were also prognostic factors for primary and secondary endpoints.
EUROPEAN HEART JOURNAL
(2022)
Review
Cardiac & Cardiovascular Systems
Amin Daoulah, Abdulaziz Alasmari, Ahmad S. Hersi, Mohammed Alshehri, Turki Al Garni, Reda Abuelatta, Haitham Amin, Wael Almahmeed, Alwaleed Aljohar, Bader K. Abumelha, Badr Alzahrani, Mohamed Ajaz Ghani, Nooraldaem Yousif, Shahrukh Hashmani, Salem M. Al-Faifi, Hameedullah M. Kazim, Wael Refaat, Ziad Dahdouh, Feras Khaliel, Jairam Aithal, Ahmed Elmahrouk, Ahmed M. Ibrahim, Abdelmaksoud Elganady, Mohammed A. Qutub, Mohamed N. Alama, Abdulwali Abohasan, Taher Hassan, Mohammed Balghith, Abdulrahman M. Alqahtani, Ahmed F. Abdelaziz, Issam Altnji, Adnan Fathey Hussien, Ibrahim A. M. Abdulhabeeb, Osama Ahmad, Mamdouh M. Haddara, Abdulrahman H. Alqahtani, Saif S. Alshahrani, Wael Qenawi, Mohamed H. Izzeldin, Osama El-Sayed, Ahmed Jamjoom, Abdulrahman Al Moghairi, Hussein Al Amri, Waleed Moubark Ibrahim, Mohsen M. Alarbash, Tajammul Hussain, Fahad Shamsi, Ehab Selim, Mohamed Ramadan, Hani Al-Sergani, Tahir Mohamed, Abdulwahab Al Khalifa, Niranjan Hiremath, Amira Ali Taha Ibrahim, Hassane Abdallah, Amr Elprince, Ahmed Diab, Diaa Eldin A. Seoud, Ahmed A. Alghamdi, Khaled E. Alebrahim, Duna Basudan, Faisal Omar M. Al Nasser, Ibrahim Ahmed Abuagila Ali, Abeer M. Shawky, Ahmed Ghonim, Abdullah Al Khushail, Maun N. Feteih, Seraj Abualnaja, Bandar Alhaddadi, Sameer Alhamid, Waleed A. Ahmed, Zainab M. Jafary, Samir Ahnia, Jala Gasem, Shahad Alaydarous, Tamer Khatab, Ataaelrahman Mohamed, Mohamed Maghrabi, Faisal Al Samadi, Tareef H. Kannout, Najeeb Mahrous, Yahya Almaleh, Adil B. Al Riyami, Altayyeb Yousef, Mohammed Ali Ahmed, Ruqayyah Ali Ahmed, Wael Tawfik, Nasser Almegreb, Mazen S. Faden, Ejazul Haq, Salah N. AlOtaibi, Akram Eldesoky, Francis A. Clarkson, Amir Lotfi
Summary: This study evaluates the clinical outcomes of ULMCA PCI compared to CABG in patients requiring revascularization in three Gulf countries. The findings suggest that while patients undergoing PCI had more comorbidities and lower ejection fractions, there was no difference in revascularization, MACCE, or total mortality between PCI and CABG during the follow-up period.
CURRENT PROBLEMS IN CARDIOLOGY
(2022)
Editorial Material
Cardiac & Cardiovascular Systems
James Muller, Patrick Serruys, Niel Grubb, John Pastore
EUROPEAN HEART JOURNAL
(2023)
Letter
Cardiac & Cardiovascular Systems
Tsung-Ying Tsai, Yoshinobu Onuma, Patrick W. Serruys
INTERNATIONAL JOURNAL OF CARDIOLOGY
(2023)
Article
Cardiac & Cardiovascular Systems
Kamil Bujak, Pablo Vidal-Cales, Rami Gabani, Riccardo Rinaldi, Josep Gomez-Lara, Luis Ortega-Paz, Victor Jimenez-Diaz, Marcelo Jimenez-Kockar, Pilar Jimenez-Quevedo, Roberto Diletti, Gianluca Campo, Antonio Silvestro, Jaume Maristany, Xacobe Flores, Loreto Oyarzabal, Antonio De Miguel-Castro, Andres Iniguez, Luis Nombela-Franco, Alfonso Ielasi, Maurizio Tespili, Mattie Lenzen, Simone Biscaglia, Soheil Al-Shaiban, Rafael Romaguera, Joan Antoni Gomez-Hospital, Mariusz Gasior, Patrick W. Serruys, Manel Sabate, Salvatore Brugaletta
Summary: This study aims to analyze the relationship between total stent length (TSL) and 10-year target-lesion failure (TLF) in patients with ST-elevation myocardial infarction (STEMI) treated with percutaneous coronary intervention. The results show that there is a direct relationship between TSL and the risk of TLF at 10 years, mainly driven by target lesion revascularization (TLR).
AMERICAN HEART JOURNAL
(2023)
Article
Cardiac & Cardiovascular Systems
Victor Arevalos, Francesco Spione, Rami Gabani, Luis Ortega-Paz, Josep Gomez-Lara, Victor Jimenez-Diaz, Marcelo Jimenez, Pilar Jimenez-Quevedo, Roberto Diletti, Javier Pineda, Gianluca Campo, Antonio Silvestro, Jaume Maristany, Xacobe Flores, Loreto Oyarzabal, Guillermo Bastos-Fernandez, Andres Iniguez, Antonio Serra, Javier Escaned, Alfonso Ielasi, Maurizio Tespili, Mattie Lenzen, Antonio Fernandez-Ortiz, Pascual Bordes, Matteo Tebaldi, Simone Biscaglia, Soheil Al-Shaibani, Rafael Romaguera, Joan Antoni Gomez-Hospital, Josep Rodes-Cabau, Patrick W. Serruys, Manel Sabate, Salvatore Brugaletta
Summary: The aim of this substudy was to examine the influence of patient age on the long-term outcomes of ST-elevation myocardial infarction (STEMI). The study included 1,375 patients with STEMI and categorized them into four age groups. The results showed that patients younger than 55 years, patients aged 55 to 65 years, and patients aged 65 to 75 years had lower risks of patient-oriented composite end point (POCE) compared to those older than 75 years, primarily due to lower rates of all-cause death and cardiac death.
AMERICAN JOURNAL OF CARDIOLOGY
(2023)
Article
Cardiac & Cardiovascular Systems
Felice Gragnano, Roxana Mehran, Mattia Branca, Anna Franzone, Usman Baber, Yangsoo Jang, Takeshi Kimura, Joo-Yong Hahn, Qiang Zhao, Stephan Windecker, Charles M. Gibson, Byeong-Keuk Kim, Hirotoshi Watanabe, Young Bin Song, Yunpeng Zhu, Pascal Vranckx, Shamir Mehta, Sung-Jin Hong, Kenji Ando, Hyeon-Cheol Gwon, Paolo Calabro, Patrick W. Serruys, George D. Dangas, Eugene P. McFadden, Dominick J. Angiolillo, Dik Heg, Marco Valgimigli
Summary: This study suggests that P2Y12 inhibitor monotherapy after complex percutaneous coronary intervention (PCI) can preserve ischemic protection while limiting bleeding risk. Compared with dual antiplatelet therapy (DAPT), P2Y12 inhibitor monotherapy after 1-month to 3-month DAPT can reduce the major bleeding risk in complex PCI patients.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
(2023)
Article
Cardiac & Cardiovascular Systems
Hesham Elzomor, Timotheus J. Neumann, Linus Boas, Philipp Ruile, Mahmoud Abdelshafy, Ahmed Elkoumy, Pruthvi C. Revaiah, Tsung-Ying Tsai, Klaus Kaier, Osama Soliman, Miroslaw Ferenc, Dirk Westermann, Franz-Josef Neumann, Patrick Serruys, Simon Schoechlin
Summary: Background estimation of regurgitant fraction using videodensitometry (VD-AR) is a new objective grading tool for paravalvular regurgitation (PVR) after transcatheter aortic valve implantation (TAVI). This study found that VD-AR > 17% was independently associated with 3-year mortality. Compared to subjective visual evaluation, VD-AR resulted in a smaller proportion of patients classified as prognostically relevant for PVR.
CLINICAL RESEARCH IN CARDIOLOGY
(2023)
Article
Cardiac & Cardiovascular Systems
Pruthvi C. Revaiah, Patrick W. Serruys, Denise P. Yates, Yoshinobu Onuma, Jose Luis Zamorano
Summary: This article reports on the use of CCTA to non-invasively risk stratify and guide further management of patients with non-obstructive CAD. In the case presented, CCTA showed lipid-rich plaques in the left main stem and left anterior descending arteries, and the patient remained asymptomatic after treatment. The discussion highlights the value of CCTA as a diagnostic tool for assisting in the diagnosis and treatment of patients with non-obstructive CAD.
EUROPEAN HEART JOURNAL-CASE REPORTS
(2023)
Article
Cardiac & Cardiovascular Systems
Nozomi Kotoku, Patrick W. Serruys, Kai Ninomiya, Alan Soo, Shinichiro Masuda, Shigetaka Kageyama, Pruthvi C. Revaiah, Michael J. Mack, David R. Holmes, Marie -Claude Morice, Piroze M. Davierwala, Friedrich W. Mohr, Milan Milojevic, Arie Pieter Kappetein, Scot Garg, Yoshinobu Onuma
Summary: This study aimed to evaluate the impact of non-fatal periprocedural major adverse events (PMAE) on 10-year mortality and investigate whether PMAE affect mortality predicted by SYNTAX score II 2020 (SSII-2020) and whether optimal medical therapy (OMT) has a positive effect on the prognosis of patients with non-fatal PMAE. The results show that non-fatal PMAE are more common following CABG than PCI, but their prognostic impact is similar, being significant in the first year and then diminishing out to 10 years. Therefore, patients with non-fatal PMAE may require more careful follow-up and additional preventive treatment in the first year post-procedure.
Meeting Abstract
Cardiac & Cardiovascular Systems
Kai Ninomiya, Shigetaka Kageyama, Hiroki Shiomi, Nozomi Kotoku, Shinichiro Masuda, Pruthvi Revaiah, Scot Garg, Neil O'leary, Takeshi Kimura, Yoshinobu Onuma, Patrick Serruys, Patrick Serruys
JACC-CARDIOVASCULAR INTERVENTIONS
(2023)
Meeting Abstract
Cardiac & Cardiovascular Systems
Pruthvi Chenniganahosahalli Revaiah, Asishkumar Mandalay, Gunasekaran Sengottuvelu, Ahmed Elkoumy, Hesham Elzomor, Mahmoud Abdelshafy, Sanjeev Bhatt, Yoshinobu Onuma, Osama Soliman, Patrick W. Serruys
JACC-CARDIOVASCULAR INTERVENTIONS
(2023)
Meeting Abstract
Cardiac & Cardiovascular Systems
Pruthvi Chenniganahosahalli Revaiah, Schinichiro Masuda, Shigetaka Kageyama, Kai Ninomiya, Nozomi Kotoku, Bo Wang, He Xingqiang, Yoshinobu Onuma, Patrick W. Serruys
JACC-CARDIOVASCULAR INTERVENTIONS
(2023)
Meeting Abstract
Cardiac & Cardiovascular Systems
Patrick Serruys, Kai Ninomiya, Jinying Zhou, Nozomi Kotoku, Shigetaka Kageyama, Shinichiro Masuda, Yoshinobu Onuma
JACC-CARDIOVASCULAR INTERVENTIONS
(2023)
Meeting Abstract
Cardiac & Cardiovascular Systems
TsungYing Tsai, Shigetaka Kageyama, Yoshinobu Onuma, Giulio Pompilio, Daniele Andreini, Saima Mushtaq, Gianluca Pontone, Gianluca Pontone, Mark La Meir, Johan De Mey, Kaoru Tanaka, Torsten Doenst, Ulf Teichgraeber, Ulf Teichgraeber, Ulrich Schneider, John Puskas, Jagat Narula, Patrick W. Serruys
JACC-CARDIOVASCULAR INTERVENTIONS
(2023)
Meeting Abstract
Cardiac & Cardiovascular Systems
Bo Wang, Randall Lee, Yoshinobu Onuma, Patrick W. J. C. Serruys, Ling Tao
JACC-CARDIOVASCULAR INTERVENTIONS
(2023)
Meeting Abstract
Cardiac & Cardiovascular Systems
Kai Ninomiya, Shigetaka Kageyama, Hiroki Shiomi, Shinichiro Masuda, Nozomi Kotoku, Pruthvi Revaiah, Scot Garg, Neil O'Leary, Takeshi Kimura, Yoshinobu Onuma, Patrick W. Serruys
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
(2023)