Design of a New Peptide Substrate Probe of the Putative Biomarker Legumain with Potential Application in Prostate Cancer Diagnosis Ex Vivo

Fluorogenic reaction-based prodrug conjugates as targeted cancer theranostics

(2018) Min Hee Lee et al.   CHEMICAL SOCIETY REVIEWS

MIP-Based Sensors: Promising New Tools for Cancer Biomarker Determination

(2017) Giulia Selvolini et al.   SENSORS

Structure and function of legumain in health and disease

(2016) Elfriede Dall et al.   BIOCHIMIE

Cancer statistics, 2016

(2016) Rebecca L. Siegel et al.   CA-A CANCER JOURNAL FOR CLINICIANS

PSA and beyond: alternative prostate cancer biomarkers

(2016) Sharanjot Saini   CELLULAR ONCOLOGY

High expression of the cysteine proteinase legumain in colorectal cancer – Implications for therapeutic targeting

(2015) Mads H. Haugen et al.   EUROPEAN JOURNAL OF CANCER

A single design strategy for dual sensitive pH probe with a suitable range to map pH in living cells

(2015) Kang-Kang Yu et al.   Scientific Reports

Ultrasensitive internally quenched substrates of human cathepsin L

(2014) Monika Łęgowska et al.   ANALYTICAL BIOCHEMISTRY

Synthesis of a novel legumain-cleavable colchicine prodrug with cell-specific toxicity

(2014) Robert Løvsletten Smith et al.   BIOORGANIC & MEDICINAL CHEMISTRY

A broad spectrum dark quencher: construction of multiple colour protease and photolytic sensors

(2013) Finith E. Jernigan et al.   CHEMICAL COMMUNICATIONS

Cathepsin L inhibition by the small molecule KGP94 suppresses tumor microenvironment enhanced metastasis associated cell functions of prostate and breast cancer cells

(2013) Dhivya R. Sudhan et al.   CLINICAL & EXPERIMENTAL METASTASIS

Mechanistic and structural studies on legumain explain its zymogenicity, distinct activation pathways, and regulation

(2013) E. Dall et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Legumain: A biomarker for diagnosis and prognosis of human ovarian cancer

(2012) Lina Wang et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Functional Imaging of Legumain in Cancer Using a New Quenched Activity-Based Probe

(2012) Laura E. Edgington et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Association of legumain expression pattern with prostate cancer invasiveness and aggressiveness

(2012) Yoshio Ohno et al.   WORLD JOURNAL OF UROLOGY

Power and limits of modern cancer diagnostics: cancer of unknown primary

(2011) K. Hemminki et al.   ANNALS OF ONCOLOGY

Functional imaging of proteases: recent advances in the design and application of substrate-based and activity-based probes

(2011) Laura E Edgington et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Targeting Cell Surface Alpha(v)beta(3) Integrin Increases Therapeutic Efficacies of a Legumain Protease-Activated Auristatin Prodrug

(2011) Yuan Liu et al.   MOLECULAR PHARMACEUTICS

A Novel Antitumor Prodrug Platform Designed to Be Cleaved by the Endoprotease Legumain

(2009) Liron Stern et al.   BIOCONJUGATE CHEMISTRY

Synthesis and applications of Rhodamine derivatives as fluorescent probes

(2009) Mariana Beija et al.   CHEMICAL SOCIETY REVIEWS