A Curcumin Derivative Activates TFEB and Protects Against Parkinsonian Neurotoxicity in Vitro

A small molecule transcription factor EB activator ameliorates beta‐amyloid precursor protein and Tau pathology in Alzheimer's disease models

(2019) Ju‐Xian Song et al.   AGING CELL

Chloroquine inhibits autophagic flux by decreasing autophagosome-lysosome fusion

(2018) Mario Mauthe et al.   Autophagy

The complex relationship between TFEB transcription factor phosphorylation and subcellular localization

(2018) Rosa Puertollano et al.   EMBO JOURNAL

Overexpression of TFEB Drives a Pleiotropic Neurotrophic Effect and Prevents Parkinson’s Disease-Related Neurodegeneration

(2018) Albert Torra et al.   MOLECULAR THERAPY

MAP4K3 mediates amino acid-dependent regulation of autophagy via phosphorylation of TFEB

(2018) Cynthia L. Hsu et al.   Nature Communications

Neuroprotective Natural Products for the Treatment of Parkinson's Disease by Targeting the Autophagy-Lysosome Pathway: A Systematic Review

(2017) Zi-Ying Wang et al.   PHYTOTHERAPY RESEARCH

Parkinson disease

(2017) Werner Poewe et al.   Nature Reviews Disease Primers

A novel curcumin analog binds to and activates TFEB in vitro and in vivo independent of MTOR inhibition

(2016) Ju-Xian Song et al.   Autophagy

TFEB at a glance

(2016) Gennaro Napolitano et al.   JOURNAL OF CELL SCIENCE

Mild MPP+exposure impairs autophagic degradation through a novel lysosomal acidity-independent mechanism

(2016) Masatsugu Miyara et al.   JOURNAL OF NEUROCHEMISTRY

An Autophagic Flux Probe that Releases an Internal Control

(2016) Takeshi Kaizuka et al.   MOLECULAR CELL

Parkinson's disease

(2015) Lorraine V Kalia et al.   LANCET

Lysosomal calcium signalling regulates autophagy through calcineurin and TFEB

(2015) Diego L. Medina et al.   NATURE CELL BIOLOGY

Restoring impaired protein metabolism in Parkinson's disease - TFEB-mediated autophagy as a novel therapeutic target

(2014) Darius Ebrahimi-Fakhari et al.   MOVEMENT DISORDERS

Roles of Autophagy in MPP+-Induced Neurotoxicity In Vivo: The Involvement of Mitochondria and α-Synuclein Aggregation

(2014) Kai-Chih Hung et al.   PLoS One

TFEB

(2013) Mickael Decressac et al.   Autophagy

α-lipoic acid protects dopaminergic neurons against MPP+-induced apoptosis by attenuating reactive oxygen species formation

(2013) DA-WEI LI et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

How Parkinsonian Toxins Dysregulate the Autophagy Machinery

(2013) Ruben Dagda et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

TFEB-mediated autophagy rescues midbrain dopamine neurons from  -synuclein toxicity

(2013) M. Decressac et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Role of Autophagy in Parkinson's Disease

(2013) M. A. Lynch-Day et al.   Cold Spring Harbor Perspectives in Medicine

MTORC1 functions as a transcriptional regulator of autophagy by preventing nuclear transport of TFEB

(2012) Jose A. Martina et al.   Autophagy

A lysosome-to-nucleus signalling mechanism senses and regulates the lysosome via mTOR and TFEB

(2012) Carmine Settembre et al.   EMBO JOURNAL

The Transcription Factor TFEB Links mTORC1 Signaling to Transcriptional Control of Lysosome Homeostasis

(2012) A. Roczniak-Ferguson et al.   Science Signaling

Impaired autophagy due to constitutive mTOR activation sensitizes TSC2-null cells to cell death under stress

(2011) Shukie Ng et al.   Autophagy

Pathogenic Lysosomal Depletion in Parkinson's Disease

(2010) B. Dehay et al.   JOURNAL OF NEUROSCIENCE

Autophagy gone awry in neurodegenerative diseases

(2010) Esther Wong et al.   NATURE NEUROSCIENCE

A Gene Network Regulating Lysosomal Biogenesis and Function

(2009) Marco Sardiello et al.   SCIENCE

A review of Parkinson's disease

(2008) C. A. Davie   BRITISH MEDICAL BULLETIN