Underestimated Aspect of Mucopolysaccharidosis Pathogenesis: Global Changes in Cellular Processes Revealed by Transcriptomic Studies

Changes in cellular processes occurring in mucopolysaccharidoses as underestimated pathomechanisms of these diseases

(2019) Lidia Gaffke et al.   CELL BIOLOGY INTERNATIONAL

Trehalose reduces retinal degeneration, neuroinflammation and storage burden caused by a lysosomal hydrolase deficiency

(2018) Parisa Lotfi et al.   Autophagy

Intestinal Epithelial Cell-specific Deletion of α-Mannosidase II Ameliorates Experimental Colitis

(2018) Koichiro Suzuki et al.   CELL STRUCTURE AND FUNCTION

Regulation of Clusterin Gene Expression

(2018) Marilina Garcia-Aranda et al.   CURRENT PROTEIN & PEPTIDE SCIENCE

The pathogenesis of lysosomal storage disorders: beyond the engorgement of lysosomes to abnormal development and neuroinflammation

(2018) Maria Teresa Fiorenza et al.   HUMAN MOLECULAR GENETICS

Lactadherin: An unappreciated haemostasis regulator and potential therapeutic agent

(2018) Agnieszka Kamińska et al.   VASCULAR PHARMACOLOGY

Recent trends in mucopolysaccharidosis research

(2018) Hiroshi Kobayashi   JOURNAL OF HUMAN GENETICS

Proteomic analysis of mucopolysaccharidosis I mouse brain with two-dimensional polyacrylamide gel electrophoresis

(2017) Li Ou et al.   MOLECULAR GENETICS AND METABOLISM

Genetic factors influencing the reduction of central corneal thickness in disorders affecting the eye

(2017) Joanna Swierkowska et al.   OPHTHALMIC GENETICS

The transcription factor ATF5: role in cellular differentiation, stress responses, and cancer

(2017) Thomas K. Sears et al.   Oncotarget

Periostin function in communication with extracellular matrices

(2017) Akira Kudo et al.   Journal of Cell Communication and Signaling

Structure of the Elastin-Contractile Units in the Thoracic Aorta and How Genes That Cause Thoracic Aortic Aneurysms and Dissections Disrupt This Structure

(2016) Ashkan Karimi et al.   CANADIAN JOURNAL OF CARDIOLOGY

Cell cycle is disturbed in mucopolysaccharidosis type II fibroblasts, and can be improved by genistein

(2016) Marta Moskot et al.   GENE

Integrated analysis of proteome and transcriptome changes in the mucopolysaccharidosis type VII mouse hippocampus

(2016) Michael K. Parente et al.   MOLECULAR GENETICS AND METABOLISM

Analysis of 589,306 genomes identifies individuals resilient to severe Mendelian childhood diseases

(2016) Rong Chen et al.   NATURE BIOTECHNOLOGY

Immune-Mediated Inflammation May Contribute to the Pathogenesis of Cardiovascular Disease in Mucopolysaccharidosis Type I

(2016) Omar Khalid et al.   PLoS One

Lysosomal storage of heparan sulfate causes mitochondrial defects, altered autophagy, and neuronal death in the mouse model of mucopolysaccharidosis III type C

(2015) Alexey V. Pshezhetsky   Autophagy

Combined Therapies for Lysosomal Storage Diseases

(2015) M. Gabig-Cimińska et al.   CURRENT MOLECULAR MEDICINE

Epigenetic repression of HOXB cluster in oral cancer cell lines

(2014) Flávia Caló Aquino Xavier et al.   ARCHIVES OF ORAL BIOLOGY

The Phytoestrogen Genistein Modulates Lysosomal Metabolism and Transcription Factor EB (TFEB) Activation

(2014) Marta Moskot et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Gelsolin: The tail of a molecular gymnast

(2013) Shalini Nag et al.   Cytoskeleton

Scavenger receptor class A member 3 (SCARA3) in disease progression and therapy resistance in multiple myeloma

(2013) Charles O. Brown et al.   LEUKEMIA RESEARCH

Lysosomal storage disorders: The cellular impact of lysosomal dysfunction

(2012) Frances M. Platt et al.   JOURNAL OF CELL BIOLOGY

Dysregulation of Gene Expression in a Lysosomal Storage Disease Varies between Brain Regions Implicating Unexpected Mechanisms of Neuropathology

(2012) Michael K. Parente et al.   PLoS One

Why are behaviors of children suffering from various neuronopathic types of mucopolysaccharidoses different?

(2010) Grzegorz Węgrzyn et al.   MEDICAL HYPOTHESES

Huntington’s disease: roles of huntingtin-interacting protein 1 (HIP-1) and its molecular partner HIPPI in the regulation of apoptosis and transcription

(2008) Nitai P. Bhattacharyya et al.   FEBS Journal