Alpha-Tocotrienol Prevents Oxidative Stress-Mediated Post-Translational Cleavage of Bcl-xL in Primary Hippocampal Neurons

Tocotrienol-Rich Fraction of Palm Oil Improves Behavioral Impairments and Regulates Metabolic Pathways in AβPP/PS1 Mice

(2018) Lina Wati Durani et al.   JOURNAL OF ALZHEIMERS DISEASE

Exploring the selectivity of inhibitor complexes with Bcl-2 and Bcl-XL: A molecular dynamics simulation approach

(2018) Naoki Wakui et al.   JOURNAL OF MOLECULAR GRAPHICS & MODELLING

Rice Bran Extract Compensates Mitochondrial Dysfunction in a Cellular Model of Early Alzheimer's Disease

(2018) Stephanie Hagl et al.   JOURNAL OF ALZHEIMERS DISEASE

α- and γ-Tocopherol Prevent Age-Related Transcriptional Alterations in the Heart and Brain of Mice

(2018) Sang-Kyu Park et al.   JOURNAL OF NUTRITION

Tocotrienol Rich Fraction Supplementation Modulate Brain Hippocampal Gene Expression in APPswe/PS1dE9 Alzheimer’s Disease Mouse Model

(2018) Wan Nurzulaikha Wan Nasri et al.   JOURNAL OF ALZHEIMERS DISEASE

ΔN-Bcl-xL, a therapeutic target for neuroprotection

(2017) Han-A Park et al.   Neural Regeneration Research

Tocotrienol-Rich Fraction Modulates Amyloid Pathology and Improves Cognitive Function in AβPP/PS1 Mice

(2016) Nor Faeizah Ibrahim et al.   JOURNAL OF ALZHEIMERS DISEASE

Bcl-xL Is Essential for the Survival and Function of Differentiated Neurons in the Cortex That Control Complex Behaviors

(2016) A. Nakamura et al.   JOURNAL OF NEUROSCIENCE

Bcl-xL Is Necessary for Neurite Outgrowth in Hippocampal Neurons

(2015) Han-A Park et al.   ANTIOXIDANTS & REDOX SIGNALING

Regulation of Bcl-xL-ATP Synthase Interaction by Mitochondrial Cyclin B1-Cyclin-Dependent Kinase-1 Determines Neuronal Survival

(2015) M. Veas-Perez de Tudela et al.   JOURNAL OF NEUROSCIENCE

Life after MOMP

(2015) Vivian Gama et al.   MOLECULAR CELL

A Tocotrienol-Enriched Formulation Protects against Radiation-Induced Changes in Cardiac Mitochondria without Modifying Late Cardiac Function or Structure

(2015) Vijayalakshmi Sridharan et al.   RADIATION RESEARCH

Regulation of mitochondrial nutrient and energy metabolism by BCL-2 family proteins

(2015) Alfredo Giménez-Cassina et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Optimizing protein precipitation efficiency for assessing the contribution of low molecular weight compounds to serum antioxidant capacity

(2014) Kristi M. Crowe   CLINICAL BIOCHEMISTRY

Tocotrienol Rich Fraction Reverses Age-Related Deficits in Spatial Learning and Memory in Aged Rats

(2014) Nursiati Mohamad Taridi et al.   LIPIDS

An uncoupling channel within the c-subunit ring of the F1FO ATP synthase is the mitochondrial permeability transition pore

(2014) K. N. Alavian et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Clinical Investigation of the Protective Effects of Palm Vitamin E Tocotrienols on Brain White Matter

(2014) Yogheswaran Gopalan et al.   STROKE

Bcl-xL in neuroprotection and plasticity

(2014) Elizabeth A. Jonas et al.   Frontiers in Physiology

PINK1 protects against cell death induced by mitochondrial depolarization, by phosphorylating Bcl-xL and impairing its pro-apoptotic cleavage

(2013) G Arena et al.   CELL DEATH AND DIFFERENTIATION

Classification and prediction of clinical diagnosis of Alzheimer's disease based on MRI and plasma measures of α-/γ-tocotrienols and γ-tocopherol

(2013) F. Mangialasche et al.   JOURNAL OF INTERNAL MEDICINE

A Bcl-xL–Drp1 complex regulates synaptic vesicle membrane dynamics during endocytosis

(2013) Hongmei Li et al.   NATURE CELL BIOLOGY

Rice bran extract protects from mitochondrial dysfunction in guinea pig brains

(2013) Stephanie Hagl et al.   PHARMACOLOGICAL RESEARCH

Anti-apoptotic MCL-1 localizes to the mitochondrial matrix and couples mitochondrial fusion to respiration

(2012) Rhonda M. Perciavalle et al.   NATURE CELL BIOLOGY

N-terminally cleaved Bcl-xL mediates ischemia-induced neuronal death

(2012) Dimitry Ofengeim et al.   NATURE NEUROSCIENCE

Culturing pyramidal neurons from the early postnatal mouse hippocampus and cortex

(2012) Gerard M J Beaudoin et al.   Nature Protocols

Multipolar functions of BCL-2 proteins link energetics to apoptosis

(2012) J. Marie Hardwick et al.   TRENDS IN CELL BIOLOGY

α-Tocotrienol quinone modulates oxidative stress response and the biochemistry of aging

(2011) William D. Shrader et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Bcl-xLregulates mitochondrial energetics by stabilizing the inner membrane potential

(2011) Ying-bei Chen et al.   JOURNAL OF CELL BIOLOGY

Tocotrienol Vitamin E Protects against Preclinical Canine Ischemic Stroke by Inducing Arteriogenesis

(2011) Cameron Rink et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Bcl-xL regulates metabolic efficiency of neurons through interaction with the mitochondrial F1FO ATP synthase

(2011) Kambiz N. Alavian et al.   NATURE CELL BIOLOGY

Bcl-xL Blocks a Mitochondrial Inner Membrane Channel and Prevents Ca2+ Overload-Mediated Cell Death

(2011) Daniel Tornero et al.   PLoS One

Natural Vitamin E α-Tocotrienol Protects Against Ischemic Stroke by Induction of Multidrug Resistance-Associated Protein 1

(2011) Han-A Park et al.   STROKE

Evidence that inhibition of BAX activation by BCL-2 involves its tight and preferential interaction with the BH3 domain of BAX

(2010) Bonsu Ku et al.   CELL RESEARCH

Glutathione disulfide induces neural cell death via a 12-lipoxygenase pathway

(2009) H-A Park et al.   CELL DEATH AND DIFFERENTIATION

Molecular Basis for Bcl-2 Homology 3 Domain Recognition in the Bcl-2 Protein Family

(2009) Gautier Moroy et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

How mitochondria produce reactive oxygen species

(2008) Michael P. Murphy   BIOCHEMICAL JOURNAL

Ischemic preconditioning blocks BAD translocation, Bcl-xL cleavage, and large channel activity in mitochondria of postischemic hippocampal neurons

(2008) T. Miyawaki et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Bcl-xL induces Drp1-dependent synapse formation in cultured hippocampal neurons

(2008) H. Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Bcl-xL Inhibitor ABT-737 Reveals a Dual Role for Bcl-xL in Synaptic Transmission

(2007) John A. Hickman et al.   JOURNAL OF NEUROPHYSIOLOGY

Postnatal developmental regulation of Bcl-2 family proteins in brain mitochondria

(2007) Lucian Soane et al.   JOURNAL OF NEUROSCIENCE RESEARCH