The 1,10-Phenanthroline Ligand Enhances the Antiproliferative Activity of DNA-Intercalating Thiourea-Pd(II) and -Pt(II) Complexes Against Cisplatin-Sensitive and -Resistant Human Ovarian Cancer Cell Lines

Fluorometric detection of protein-ligand engagement: The case of phosphodiesterase5

(2018) Giulia Di Rocco et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

Tracking antitumor metallodrugs: promising agents with the Ru(II)- and Fe(II)-cyclopentadienyl scaffolds

(2016) Tânia S Morais et al.   Future Medicinal Chemistry

DNA binding, topoisomerase inhibition and cytotoxicity of palladium(II) complexes with 1,10-phenanthroline and thioureas

(2016) Carolina V. Barra et al.   INORGANICA CHIMICA ACTA

Quantitative analysis of Gd@C82(OH)22 and cisplatin uptake in single cells by inductively coupled plasma mass spectrometry

(2015) Ling-Na Zheng et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Inside the biochemical pathways of thymidylate synthase perturbed by anticancer drugs: Novel strategies to overcome cancer chemoresistance

(2015) Laura Taddia et al.   DRUG RESISTANCE UPDATES

How the Intercalation of Phenanthroline Affects the Structure, Energetics, and Bond Properties of DNA Base Pairs: Theoretical Study Applied to Adenine–Thymine and Guanine–Cytosine Tetramers

(2015) Adrià Gil et al.   Journal of Chemical Theory and Computation

A Fatal Combination: A Thymidylate Synthase Inhibitor with DNA Damaging Activity

(2015) Anna Ligasová et al.   PLoS One

Antineoplastic DNA-Binding Compounds: Intercalating and Minor Groove Binding Drugs

(2014) Katarina Mišković et al.   Arhiv za Higijenu Rada i Toksikologiju-Archives of Industrial Hygiene and Toxicology

Cisplatin in cancer therapy: Molecular mechanisms of action

(2014) Shaloam Dasari et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Ovarian Cancer Cell Line Panel (OCCP): Clinical Importance of In Vitro Morphological Subtypes

(2014) Corine M. Beaufort et al.   PLoS One

StructureActivity Relationship of Polypyridyl Ruthenium(II) Complexes as DNA Intercalators, DNA Photocleavage Reagents, and DNA Topoisomerase and RNA Polymerase Inhibitors

(2013) Xing Chen et al.   CHEMISTRY & BIODIVERSITY

NMR characterisation and dynamic behaviour of [Pt(bipy)(R-Thiourea)2]Cl2 and [Pt(phen)(R-Thiourea)2]Cl2 complexes

(2013) Archimede Rotondo et al.   INORGANICA CHIMICA ACTA

Modulation of the expression of folate cycle enzymes and polyamine metabolism by berberine in cisplatin-sensitive and -resistant human ovarian cancer cells

(2013) GAETANO MARVERTI et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

Drug–DNA interactions and their study by UV–Visible, fluorescence spectroscopies and cyclic voltametry

(2013) Muhammad Sirajuddin et al.   JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY

Concurrent inhibition of enzymatic activity and NF-Y-mediated transcription of Topoisomerase-IIα by bis-DemethoxyCurcumin in cancer cells

(2013) S Belluti et al.   Cell Death & Disease

Drugging Topoisomerases: Lessons and Challenges

(2012) Yves Pommier   ACS Chemical Biology

Doxorubicin: an update on anticancer molecular action, toxicity and novel drug delivery systems

(2012) Oktay Tacar et al.   JOURNAL OF PHARMACY AND PHARMACOLOGY

Structural and dynamic NMR characterization of [Pd(bipy)(R-thiourea)2]2+ and [Pd(phen)(R-thiourea)2]2+ cations

(2012) Archimede Rotondo et al.   POLYHEDRON

Metal Complexes as DNA Intercalators

(2011) Hong-Ke Liu et al.   ACCOUNTS OF CHEMICAL RESEARCH

Doxorubicin pathways

(2010) Caroline F. Thorn et al.   Pharmacogenetics and Genomics

Collateral sensitivity to novel thymidylate synthase inhibitors correlates with folate cycle enzymes impairment in cisplatin-resistant human ovarian cancer cells

(2009) Gaetano Marverti et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Characterization of the cell growth inhibitory effects of a novel DNA-intercalating bipyridyl-thiourea-Pt(II) complex in cisplatin-sensitive and—resistant human ovarian cancer cells

(2009) Gaetano Marverti et al.   INVESTIGATIONAL NEW DRUGS

Recent Developments in the Chemistry of Deoxyribonucleic Acid (DNA) Intercalators: Principles, Design, Synthesis, Applications and Trends

(2009) Brenno Neto et al.   MOLECULES

Dynamics of antifolate transport via the reduced folate carrier and the membrane folate receptor in murine leukaemia cells in vitro and in vivo

(2008) Robert Mauritz et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

Platinum compounds 30 years after the introduction of cisplatin: Implications for the treatment of ovarian cancer

(2008) Franco Muggia   GYNECOLOGIC ONCOLOGY

Development of an experimental protocol for uptake studies of metal compounds in adherent tumor cells

(2008) Alexander E. Egger et al.   JOURNAL OF ANALYTICAL ATOMIC SPECTROMETRY

The Role of Cellular Accumulation in Determining Sensitivity to Platinum-Based Chemotherapy

(2007) Matthew D. Hall et al.   Annual Review of Pharmacology and Toxicology

Studies on the anti-proliferative effects of novel DNA-intercalating bipyridyl–thiourea–Pt(II) complexes against cisplatin-sensitive and -resistant human ovarian cancer cells

(2007) Gaetano Marverti et al.   JOURNAL OF INORGANIC BIOCHEMISTRY