Therapeutic targeting of soluble CD146/MCAM with the M2J‐1 monoclonal antibody prevents metastasis development and procoagulant activity in CD146‐positive invasive tumors

Blocking podoplanin suppresses growth and pulmonary metastasis of human malignant melanoma

(2019) Mengqiao Xu et al.   BMC CANCER

Gene expression profiling of single circulating tumor cells in ovarian cancer - Establishment of a multi-marker gene panel

(2016) Christina Blassl et al.   Molecular Oncology

Targeting soluble CD146 with a neutralizing antibody inhibits vascularization, growth and survival of CD146-positive tumors

(2016) J Stalin et al.   ONCOGENE

Therapeutic targeting of tetraspanin8 in epithelial ovarian cancer invasion and metastasis

(2016) C S Park et al.   ONCOGENE

A critical role of Oct4A in mediating metastasis and disease-free survival in a mouse model of ovarian cancer

(2015) Chantel Samardzija et al.   Molecular Cancer

Angiomotin promotes breast cancer cell proliferation and invasion

(2015) MENG LV et al.   ONCOLOGY REPORTS

Clinical value of circulating endothelial cells and of soluble CD146 levels in patients undergoing surgery for non-small cell lung cancer

(2014) M Ilie et al.   BRITISH JOURNAL OF CANCER

Laminins 411 and 421 differentially promote tumor cell migration via α6β1 integrin and MCAM (CD146)

(2014) Taichi Ishikawa et al.   MATRIX BIOLOGY

Monoclonal antibodies to human laminin α4 chain globular domain inhibit tumor cell adhesion and migration on laminins 411 and 421, and binding of α6β1 integrin and MCAM to α4-laminins

(2014) Taichi Ishikawa et al.   MATRIX BIOLOGY

Blood MUC-18/MCAM expression in patients with melanoma: a suitable marker of poor outcome

(2013) M.C. Rapanotti et al.   BRITISH JOURNAL OF DERMATOLOGY

Value of melanocytic-associated immunohistochemical markers in the diagnosis of malignant melanoma: a review and update

(2013) Nelson G. Ordóñez   HUMAN PATHOLOGY

Soluble Melanoma Cell Adhesion Molecule (sMCAM/sCD146) Promotes Angiogenic Effects on Endothelial Progenitor Cells through Angiomotin

(2013) Jimmy Stalin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

CD146, a multi-functional molecule beyond adhesion

(2012) Zhaoqing Wang et al.   CANCER LETTERS

CD146 Expression in Human Breast Cancer Cell Lines Induces Phenotypic and Functional Changes Observed in Epithelial to Mesenchymal Transition

(2012) Anne-Marie Imbert et al.   PLoS One

MCAM is a novel metastasis marker and regulates spreading, apoptosis and invasion of ovarian cancer cells

(2012) Zheng Wu et al.   TUMOR BIOLOGY

Up-regulation of METCAM/MUC18 promotes motility, invasion, and tumorigenesis of human breast cancer cells

(2011) Guo-fang Zeng et al.   BMC CANCER

IGFBP-4 activates the Wnt/beta-catenin signaling pathway and induces M-CAM expression in human renal cell carcinoma

(2011) Koji Ueno et al.   INTERNATIONAL JOURNAL OF CANCER

Neutralizing Monoclonal Antibody to Periostin Inhibits Ovarian Tumor Growth and Metastasis

(2011) M. Zhu et al.   MOLECULAR CANCER THERAPEUTICS

Ovarian Cancer Development and Metastasis

(2010) Ernst Lengyel   AMERICAN JOURNAL OF PATHOLOGY

Epithelial-Mesenchymal Transitions in Development and Disease

(2009) Jean Paul Thiery et al.   CELL

The Epithelial-Mesenchymal Transition Generates Cells with Properties of Stem Cells

(2008) Sendurai A. Mani et al.   CELL