Secukinumab, a fully human anti-interleukin-17A monoclonal antibody, exhibits minimal immunogenicity in patients with moderate-to-severe plaque psoriasis
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Title
Secukinumab, a fully human anti-interleukin-17A monoclonal antibody, exhibits minimal immunogenicity in patients with moderate-to-severe plaque psoriasis
Authors
Keywords
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Journal
BRITISH JOURNAL OF DERMATOLOGY
Volume 176, Issue 3, Pages 752-758
Publisher
Wiley
Online
2016-08-12
DOI
10.1111/bjd.14965
References
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Note: Only part of the references are listed.- Secukinumab, a novel anti–IL-17A antibody, shows low immunogenicity potential in human in vitro assays comparable to other marketed biotherapeutics with low clinical immunogenicity
- (2016) Anette Karle et al. mAbs
- Immunogenicity of Biotherapy Used in Psoriasis: The Science Behind the Scenes
- (2015) Denis Jullien et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- Secukinumab administration by pre-filled syringe: efficacy, safety and usability results from a randomized controlled trial in psoriasis (FEATURE)
- (2014) A. Blauvelt et al. BRITISH JOURNAL OF DERMATOLOGY
- Efficacy, safety and usability of secukinumab administration by autoinjector/pen in psoriasis: a randomized, controlled trial (JUNCTURE)
- (2014) C. Paul et al. JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY
- Secukinumab in Plaque Psoriasis — Results of Two Phase 3 Trials
- (2014) Richard G. Langley et al. NEW ENGLAND JOURNAL OF MEDICINE
- Efficacy and safety of infliximab as continuous or intermittent therapy in patients with moderate-to-severe plaque psoriasis: results of a randomized, long-term extension trial (RESTORE2)
- (2013) K. Reich et al. BRITISH JOURNAL OF DERMATOLOGY
- Influence of neutralizing antibodies to adalimumab and infliximab on the treatment of psoriasis
- (2013) T. Bito et al. BRITISH JOURNAL OF DERMATOLOGY
- Antidrug antibodies in psoriasis: a systematic review
- (2013) L. Hsu et al. BRITISH JOURNAL OF DERMATOLOGY
- Immunogenicity of anti-TNFα therapy in psoriasis: a clinical issue?
- (2013) Clara De Simone et al. EXPERT OPINION ON BIOLOGICAL THERAPY
- The 5-point Investigator’s Global Assessment (IGA) Scale: A modified tool for evaluating plaque psoriasis severity in clinical trials
- (2013) Richard G. B. Langley et al. JOURNAL OF DERMATOLOGICAL TREATMENT
- Immunogenicity of anti-TNF biologic therapies for rheumatoid arthritis
- (2013) Pauline A. van Schouwenburg et al. Nature Reviews Rheumatology
- Immunogenicity/Hypersensitivity of Biologics
- (2013) Michael W. Leach et al. TOXICOLOGIC PATHOLOGY
- Immunogenicity to Therapeutic Proteins: Impact on PK/PD and Efficacy
- (2012) Narendra Chirmule et al. AAPS Journal
- The Emerging Role of IL-17 in the Pathogenesis of Psoriasis: Preclinical and Clinical Findings
- (2012) David A. Martin et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- Global Epidemiology of Psoriasis: A Systematic Review of Incidence and Prevalence
- (2012) Rosa Parisi et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- Epidemiology and comorbidities of psoriasis patients in a national database in Taiwan
- (2011) Tsen-Fang Tsai et al. JOURNAL OF DERMATOLOGICAL SCIENCE
- Mast Cells and Neutrophils Release IL-17 through Extracellular Trap Formation in Psoriasis
- (2011) A. M. Lin et al. JOURNAL OF IMMUNOLOGY
- Immunotoxicity of monoclonal antibodies
- (2010) Jacques Descotes mAbs
- The immunogenicity of humanized and fully human antibodies
- (2010) Fiona A. Harding et al. mAbs
- Overrepresentation of IL-17A and IL-22 Producing CD8 T Cells in Lesional Skin Suggests Their Involvement in the Pathogenesis of Psoriasis
- (2010) Pieter C. M. Res et al. PLoS One
- Characterization of the interleukin-17 isoforms and receptors in lesional psoriatic skin
- (2009) C. Johansen et al. BRITISH JOURNAL OF DERMATOLOGY
- IL-17-producing CD8+ T lymphocytes from psoriasis skin plaques are cytotoxic effector cells that secrete Th17-related cytokines
- (2009) Consuelo Ortega et al. JOURNAL OF LEUKOCYTE BIOLOGY
- Psoriasis Vulgaris Lesions Contain Discrete Populations of Th1 and Th17 T Cells
- (2008) Michelle A. Lowes et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
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