4.2 Article

Ebola Virus Disease Epidemiology, Clinical Features, Management, and Prevention

Journal

INFECTIOUS DISEASE CLINICS OF NORTH AMERICA
Volume 33, Issue 4, Pages 953-+

Publisher

W B SAUNDERS CO-ELSEVIER INC
DOI: 10.1016/j.idc.2019.08.005

Keywords

Ebola; Ebola virus diseases; Ebola hemorrhagic fever; Epidemiology; Diagnosis; Treatment; Prevention; Vaccines

Funding

  1. Italian Ministry of Health
  2. PANDORA-ID-NET Consortium - European and Developing Countries Clinical Trials Partnership (EDCTP2) programme (EDCTP) [RIA2016E-1609]
  3. European Union

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Ebola virus disease (EVD) is a deadly zoonotic disease caused by the Ebola virus. There is no specific treatment approved for EVD. Supportive care and management of complications are mainstays of treatment. Effective outbreak control requires a multidisciplinary team effort applying case management, infection prevention and control practices, surveillance and contact tracing, a good laboratory service, safe and dignified burials, and social and community mobilization. This article highlights the epidemiology, clinical features, diagnosis, management, and prevention of EVD. The emerging diagnostic technologies, rapid viral characterization, geo-spatial mapping of EVD transmission, and new treatments and vaccines are discussed.

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