First-in-human phase I study of the DNA-repair inhibitor DT01 in combination with radiotherapy in patients with skin metastases from melanoma

The DNA Repair Inhibitor DT01 as a Novel Therapeutic Strategy for Chemosensitization of Colorectal Liver Metastasis

(2015) N. I. Herath et al.   MOLECULAR CANCER THERAPEUTICS

Improved Overall Survival in Melanoma with Combined Dabrafenib and Trametinib

(2015) Caroline Robert et al.   NEW ENGLAND JOURNAL OF MEDICINE

The melanoma revolution: From UV carcinogenesis to a new era in therapeutics

(2014) J. A. Lo et al.   SCIENCE

A Preclinical Study Combining the DNA Repair Inhibitor Dbait with Radiotherapy for the Treatment of Melanoma

(2014) Julian Biau et al.   NEOPLASIA

Differential TIMP3 expression affects tumor progression and angiogenesis in melanomas through regulation of directionally persistent endothelial cell migration

(2013) Asha M. Das et al.   ANGIOGENESIS

Safety and Tumor Responses with Lambrolizumab (Anti–PD-1) in Melanoma

(2013) Omid Hamid et al.   NEW ENGLAND JOURNAL OF MEDICINE

Colorectal Cancer Metastasis: The DNA Repair Inhibitor Dbait Increases Sensitivity to Hyperthermia and Improves Efficacy of Radiofrequency Ablation

(2013) Flavien Devun et al.   RADIOLOGY

Immunologic Correlates of the Abscopal Effect in a Patient with Melanoma

(2012) Michael A. Postow et al.   NEW ENGLAND JOURNAL OF MEDICINE

Pharmacokinetics and Toxicity in Rats and Monkeys of coDbait: A Therapeutic Double-stranded DNA Oligonucleotide Conjugated to Cholesterol

(2012) Anne Schlegel et al.   Molecular Therapy-Nucleic Acids

Comparison of distribution and activity of nanoparticles with short interfering DNA (Dbait) in various living systems

(2011) N Berthault et al.   CANCER GENE THERAPY

Phase II, Open-Label, Randomized Trial of the MEK1/2 Inhibitor Selumetinib as Monotherapy versus Temozolomide in Patients with Advanced Melanoma

(2011) J. M. Kirkwood et al.   CLINICAL CANCER RESEARCH

Preclinical study of the DNA repair inhibitor Dbait in combination with chemotherapy in colorectal cancer

(2011) Flavien Devun et al.   JOURNAL OF GASTROENTEROLOGY

Long-Term Survival in Patients with Metastatic Melanoma Treated with DTIC or Temozolomide

(2010) C. Kim et al.   ONCOLOGIST

Small-Molecule Drugs Mimicking DNA Damage: A New Strategy for Sensitizing Tumors to Radiotherapy

(2009) M. Quanz et al.   CLINICAL CANCER RESEARCH

Guidelines for the Evaluation of Immune Therapy Activity in Solid Tumors: Immune-Related Response Criteria

(2009) J. D. Wolchok et al.   CLINICAL CANCER RESEARCH

Skin metastases of malignant melanoma: a clinical and prognostic survey

(2009) Paola Savoia et al.   MELANOMA RESEARCH

siRNA and Innate Immunity

(2009) Marjorie Robbins et al.   OLIGONUCLEOTIDES

Hyperactivation of DNA-PK by Double-Strand Break Mimicking Molecules Disorganizes DNA Damage Response

(2009) Maria Quanz et al.   PLoS One

Identification of novel epigenetically modified genes in human melanoma via promoter methylation gene profiling

(2008) Suhu Liu et al.   Pigment Cell & Melanoma Research