The cancer/testis-antigen PRAME supports the pluripotency network and represses somatic and germ cell differentiation programs in seminomas

Germ cell neoplasiain situ(GCNIS): evolution of the current nomenclature for testicular pre-invasive germ cell malignancy

(2016) Daniel M Berney et al.   HISTOPATHOLOGY

The Transcriptome and DNA Methylome Landscapes of Human Primordial Germ Cells

(2015) Fan Guo et al.   CELL

A Unique Gene Regulatory Network Resets the Human Germline Epigenome for Development

(2015) Walfred W.C. Tang et al.   CELL

SOX17 Is a Critical Specifier of Human Primordial Germ Cell Fate

(2015) Naoko Irie et al.   CELL

BMP Inhibition in Seminomas Initiates Acquisition of Pluripotency via NODAL Signaling Resulting in Reprogramming to an Embryonal Carcinoma

(2015) Daniel Nettersheim et al.   PLoS Genetics

SOX17 links gut endoderm morphogenesis and germ layer segregation

(2014) Manuel Viotti et al.   NATURE CELL BIOLOGY

STRING v10: protein–protein interaction networks, integrated over the tree of life

(2014) Damian Szklarczyk et al.   NUCLEIC ACIDS RESEARCH

Cause and Consequence of Cancer/Testis Antigen Activation in Cancer

(2013) Angelique W. Whitehurst   Annual Review of Pharmacology and Toxicology

Oct4 switches partnering from Sox2 to Sox17 to reinterpret the enhancer code and specify endoderm

(2013) Irene Aksoy et al.   EMBO JOURNAL

Transcription Factor TFAP2C Regulates Major Programs Required for Murine Fetal Germ Cell Maintenance and Haploinsufficiency Predisposes to Teratomas in Male Mice

(2013) Jana Schemmer et al.   PLoS One

Increased PRAME-Specific CTL Killing of Acute Myeloid Leukemia Cells by Either a Novel Histone Deacetylase Inhibitor Chidamide Alone or Combined Treatment with Decitabine

(2013) Yushi Yao et al.   PLoS One

Analysis of TET Expression/Activity and 5mC Oxidation during Normal and Malignant Germ Cell Development

(2013) Daniel Nettersheim et al.   PLoS One

Establishment of a versatile seminoma model indicates cellular plasticity of germ cell tumor cells

(2012) Daniel Nettersheim et al.   GENES CHROMOSOMES & CANCER

NANOG promoter methylation and expression correlation during normal and malignant human germ cell development

(2011) Daniel Nettersheim et al.   Epigenetics

The seminoma cell line TCam-2 is sensitive to HDAC inhibitor depsipeptide but tolerates various other chemotherapeutic drugs and loss of NANOG expression

(2011) Daniel Nettersheim et al.   GENES CHROMOSOMES & CANCER

TGF-β1, EGF and FGF4 synergistically induce differentiation of the seminoma cell line TCam-2 into a cell type resembling mixed non-seminoma

(2011) D. Nettersheim et al.   INTERNATIONAL JOURNAL OF ANDROLOGY

Analysis of Gene Expression Profiles of Microdissected Cell Populations Indicates that Testicular Carcinoma In situ Is an Arrested Gonocyte

(2009) S. B. Sonne et al.   CANCER RESEARCH

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

(2009) Da Wei Huang et al.   Nature Protocols

Differential expression of SOX17 and SOX2 in germ cells and stem cells has biological and clinical implications

(2008) J de Jong et al.   JOURNAL OF PATHOLOGY

Characteristics of testicular dysgenesis syndrome and decreased expression ofSRYandSOX9in Frasier syndrome

(2008) Valérie Schumacher et al.   MOLECULAR REPRODUCTION AND DEVELOPMENT

Genome-wide analysis of cancer/testis gene expression

(2008) O. Hofmann et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA