Altered gene regulation as a candidate mechanism by which ciliopathy gene SDCCAG8 contributes to schizophrenia and cognitive function

Heritability of Schizophrenia and Schizophrenia Spectrum Based on the Nationwide Danish Twin Register

(2018) Rikke Hilker et al.   BIOLOGICAL PSYCHIATRY

Centrobin controls primary ciliogenesis in vertebrates

(2018) Yetunde Adesanya Ogungbenro et al.   JOURNAL OF CELL BIOLOGY

Genome-wide association meta-analysis in 269,867 individuals identifies new genetic and functional links to intelligence

(2018) Jeanne E. Savage et al.   NATURE GENETICS

Common schizophrenia alleles are enriched in mutation-intolerant genes and in regions under strong background selection

(2018) Antonio F. Pardiñas et al.   NATURE GENETICS

Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals

(2018) James J. Lee et al.   NATURE GENETICS

Cell migration in schizophrenia: Patient-derived cells do not regulate motility in response to extracellular matrix

(2017) Jing Yang Tee et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Centriole splitting caused by loss of the centrosomal linker protein C-NAP1 reduces centriolar satellite density and impedes centrosome amplification

(2017) Anne-Marie Flanagan et al.   MOLECULAR BIOLOGY OF THE CELL

CEP164-null cells generated by genome editing show a ciliation defect with intact DNA repair capacity

(2016) Owen M. Daly et al.   JOURNAL OF CELL SCIENCE

Schizophrenia risk from complex variation of complement component 4

(2016) Aswin Sekar et al.   NATURE

SDCCAG8 Interacts with RAB Effector Proteins RABEP2 and ERC1 and Is Required for Hedgehog Signaling

(2016) Rannar Airik et al.   PLoS One

Centrosomes in the DNA damage response—the hub outside the centre

(2015) Lisa I. Mullee et al.   CHROMOSOME RESEARCH

Centrosome function and assembly in animal cells

(2015) Paul T. Conduit et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Developmental disruptions underlying brain abnormalities in ciliopathies

(2015) Jiami Guo et al.   Nature Communications

MAGMA: Generalized Gene-Set Analysis of GWAS Data

(2015) Christiaan A. de Leeuw et al.   PLoS Computational Biology

Network-Based Analysis of Schizophrenia Genome-Wide Association Data to Detect the Joint Functional Association Signals

(2015) Suhua Chang et al.   PLoS One

HTSeq--a Python framework to work with high-throughput sequencing data

(2014) S. Anders et al.   BIOINFORMATICS

Renal-Retinal Ciliopathy Gene Sdccag8 Regulates DNA Damage Response Signaling

(2014) R. Airik et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility

(2014) Anubha Mahajan et al.   NATURE GENETICS

Primary Cilia in the Developing and Mature Brain

(2014) Alicia Guemez-Gamboa et al.   NEURON

SDCCAG8 Regulates Pericentriolar Material Recruitment and Neuronal Migration in the Developing Cortex

(2014) Ryan Insolera et al.   NEURON

MiCroKiTS 4.0: a database of midbody, centrosome, kinetochore, telomere and spindle

(2014) Zhengnan Huang et al.   NUCLEIC ACIDS RESEARCH

Cep164 triggers ciliogenesis by recruiting Tau tubulin kinase 2 to the mother centriole

(2014) L.  ajanek et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Schizophrenia and the risk of cardiovascular diseases: A meta-analysis of thirteen cohort studies

(2013) Zuoxu Fan et al.   JOURNAL OF PSYCHIATRIC RESEARCH

Molecular genetic evidence for overlap between general cognitive ability and risk for schizophrenia: a report from the Cognitive Genomics consorTium (COGENT)

(2013) T Lencz et al.   MOLECULAR PSYCHIATRY

Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease

(2013) Jean-Charles Lambert et al.   NATURE GENETICS

CentrosomeDB: a new generation of the centrosomal proteins database forHumanandDrosophila melanogaster

(2013) Joao Miguel da Conceiçao Alves-Cruzeiro et al.   NUCLEIC ACIDS RESEARCH

Multiplex Genome Engineering Using CRISPR/Cas Systems

(2013) L. Cong et al.   SCIENCE

STAR: ultrafast universal RNA-seq aligner

(2012) Alexander Dobin et al.   BIOINFORMATICS

The Spinocerebellar Ataxia-Associated Gene Tau Tubulin Kinase 2 Controls the Initiation of Ciliogenesis

(2012) Sarah C. Goetz et al.   CELL

Centrosome movements in vivo correlate with specific neurite formation downstream of LIM homeodomain transcription factor activity

(2012) E. F. Andersen et al.   DEVELOPMENT

Bardet–Biedl syndrome

(2012) Elizabeth Forsythe et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Genetic risk factors for ischaemic stroke and its subtypes (the METASTROKE Collaboration): a meta-analysis of genome-wide association studies

(2012) Matthew Traylor et al.   LANCET NEUROLOGY

Genome-wide significant associations in schizophrenia to ITIH3/4, CACNA1C and SDCCAG8, and extensive replication of associations reported by the Schizophrenia PGC

(2012) M L Hamshere et al.   MOLECULAR PSYCHIATRY

A Simple Cell-Based Assay Reveals That Diverse Neuropsychiatric Risk Genes Converge on Primary Cilia

(2012) Aaron Marley et al.   PLoS One

Centrosomes, microtubules and neuronal development

(2011) Marijn Kuijpers et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease

(2011) Heribert Schunkert et al.   NATURE GENETICS

Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47

(2011) Carl A Anderson et al.   NATURE GENETICS

Ciliopathies

(2011) Friedhelm Hildebrandt et al.   NEW ENGLAND JOURNAL OF MEDICINE

Mutation analysis in Bardet–Biedl syndrome by DNA pooling and massively parallel resequencing in 105 individuals

(2010) Sabine Janssen et al.   HUMAN GENETICS

Candidate exome capture identifies mutation of SDCCAG8 as the cause of a retinal-renal ciliopathy

(2010) Edgar A Otto et al.   NATURE GENETICS

Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci

(2010) Andre Franke et al.   NATURE GENETICS

Sonic hedgehog as a chemoattractant for adult NPCs

(2010) Catherine Hong Huan Hor et al.   Cell Adhesion & Migration

Recruitment of PCM1 to the Centrosome by the Cooperative Action of DISC1 and BBS4

(2008) Atsushi Kamiya et al.   ARCHIVES OF GENERAL PSYCHIATRY

CP110 Suppresses Primary Cilia Formation through Its Interaction with CEP290, a Protein Deficient in Human Ciliary Disease

(2008) William Y. Tsang et al.   DEVELOPMENTAL CELL

Building a spindle of the correct length in human cells requires the interaction between TPX2 and Aurora A

(2008) Alexander W. Bird et al.   JOURNAL OF CELL BIOLOGY