Incorporating external information to improve sparse signal detection in rare‐variant gene‐set‐based analyses

FunSPU: A versatile and adaptive multiple functional annotation-based association test of whole-genome sequencing data

(2019) Yiding Ma et al.   PLoS Genetics

Integrating eQTL data with GWAS summary statistics in pathway-based analysis with application to schizophrenia

(2018) Chong Wu et al.   GENETIC EPIDEMIOLOGY

Randomized, Double-Blind, Placebo-Controlled, Phase 2 Trial of BMS-986020, a Lysophosphatidic Acid Receptor Antagonist for the Treatment of Idiopathic Pulmonary Fibrosis

(2018) Scott M. Palmer et al.   CHEST

Analysis of protein-coding genetic variation in 60,706 humans

(2016) Monkol Lek et al.   NATURE

The BioGRID interaction database: 2017 update

(2016) Andrew Chatr-aryamontri et al.   NUCLEIC ACIDS RESEARCH

A Powerful Pathway-Based Adaptive Test for Genetic Association with Common or Rare Variants

(2015) Wei Pan et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Exome sequencing in amyotrophic lateral sclerosis identifies risk genes and pathways

(2015) E. T. Cirulli et al.   SCIENCE

The Genotype-Tissue Expression (GTEx) pilot analysis: Multitissue gene regulation in humans

(2015) et al.   SCIENCE

The Molecular Signatures Database Hallmark Gene Set Collection

(2015) Arthur Liberzon et al.   Cell Systems

Analytical p-value calculation for the higher criticism test in finite-d problems

(2014) I. J. Barnett et al.   BIOMETRIKA

Translating biological findings into new treatment strategies for amyotrophic lateral sclerosis (ALS)

(2014) Lindsay Poppe et al.   EXPERIMENTAL NEUROLOGY

Genic Intolerance to Functional Variation and the Interpretation of Personal Genomes

(2013) Slavé Petrovski et al.   PLoS Genetics

Optimal tests for rare variant effects in sequencing association studies

(2012) S. Lee et al.   BIOSTATISTICS

Rare-Variant Association Testing for Sequencing Data with the Sequence Kernel Association Test

(2011) Michael C. Wu et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Comparison of statistical tests for disease association with rare variants

(2011) Saonli Basu et al.   GENETIC EPIDEMIOLOGY

Testing for an Unusual Distribution of Rare Variants

(2011) Benjamin M. Neale et al.   PLoS Genetics

A Data-Adaptive Sum Test for Disease Association with Multiple Common or Rare Variants

(2010) Fang Han et al.   HUMAN HEREDITY

Genome-Wide Significance Levels and Weighted Hypothesis Testing

(2010) Kathryn Roeder et al.   STATISTICAL SCIENCE

A Groupwise Association Test for Rare Mutations Using a Weighted Sum Statistic

(2009) Bo Eskerod Madsen et al.   PLoS Genetics