Physics-Based Simulations to Predict the Differential Effects of Motor Control and Musculoskeletal Deficits on Gait Dysfunction in Cerebral Palsy: A Retrospective Case Study

Muscle synergies demonstrate only minimal changes after treatment in cerebral palsy

(2019) Benjamin R. Shuman et al.   Journal of NeuroEngineering and Rehabilitation

Can altered muscle synergies control unimpaired gait?

(2019) Naser Mehrabi et al.   JOURNAL OF BIOMECHANICS

SimCP: A Simulation Platform to Predict Gait Performance Following Orthopedic Intervention in Children With Cerebral Palsy

(2019) Lorenzo Pitto et al.   Frontiers in Neurorobotics

Rapid predictive simulations with complex musculoskeletal models suggest that diverse healthy and pathological human gaits can emerge from similar control strategies

(2019) Antoine Falisse et al.   Journal of the Royal Society Interface

Algorithmic differentiation improves the computational efficiency of OpenSim-based trajectory optimization of human movement

(2019) Antoine Falisse et al.   PLoS One

Predicting gait adaptations due to ankle plantarflexor muscle weakness and contracture using physics-based musculoskeletal simulations

(2019) Carmichael F. Ong et al.   PLoS Computational Biology

Predictive Simulations of Neuromuscular Coordination and Joint-Contact Loading in Human Gait

(2018) Yi-Chung Lin et al.   ANNALS OF BIOMEDICAL ENGINEERING

Predictive neuromechanical simulations indicate why walking performance declines with ageing

(2018) Seungmoon Song et al.   JOURNAL OF PHYSIOLOGY-LONDON

O 046 – A flexible omnibus matching algorithm (FOMA) to support treatment decisions for children with cerebral palsy

(2018) Michael H. Schwartz   GAIT & POSTURE

OpenSim: Simulating musculoskeletal dynamics and neuromuscular control to study human and animal movement

(2018) Ajay Seth et al.   PLoS Computational Biology

A spasticity model based on feedback from muscle force explains muscle activity during passive stretches and gait in children with cerebral palsy

(2018) Antoine Falisse et al.   PLoS One

Estimating the effect size of surgery to improve walking in children with cerebral palsy from retrospective observational clinical data

(2018) Apoorva Rajagopal et al.   Scientific Reports

EMG-Driven Optimal Estimation of Subject-SPECIFIC Hill Model Muscle–Tendon Parameters of the Knee Joint Actuators

(2017) Antoine Falisse et al.   IEEE TRANSACTIONS ON BIOMEDICAL ENGINEERING

Crouch severity is a poor predictor of elevated oxygen consumption in cerebral palsy

(2017) Katherine M. Steele et al.   JOURNAL OF BIOMECHANICS

Evaluation of Direct Collocation Optimal Control Problem Formulations for Solving the Muscle Redundancy Problem

(2016) Friedl De Groote et al.   ANNALS OF BIOMEDICAL ENGINEERING

Dynamic motor control is associated with treatment outcomes for children with cerebral palsy

(2016) Michael H Schwartz et al.   DEVELOPMENTAL MEDICINE AND CHILD NEUROLOGY

Neuro-musculoskeletal simulation of instrumented contracture and spasticity assessment in children with cerebral palsy

(2016) Marjolein Margaretha van der Krogt et al.   Journal of NeuroEngineering and Rehabilitation

Stretching Your Energetic Budget: How Tendon Compliance Affects the Metabolic Cost of Running

(2016) Thomas K. Uchida et al.   PLoS One

Muscle synergies and complexity of neuromuscular control during gait in cerebral palsy

(2015) Katherine M Steele et al.   DEVELOPMENTAL MEDICINE AND CHILD NEUROLOGY

A neural circuitry that emphasizes spinal feedback generates diverse behaviours of human locomotion

(2015) Seungmoon Song et al.   JOURNAL OF PHYSIOLOGY-LONDON

A comparison of muscle energy models for simulating human walking in three dimensions

(2014) Ross H. Miller   JOURNAL OF BIOMECHANICS

Hip contact force in presence of aberrant bone geometry during normal and pathological gait

(2014) Lode Bosmans et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

High resolution muscle measurements provide insights into equinus contractures in patients with cerebral palsy

(2014) Margie A. Mathewson et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

Task constraints and minimization of muscle effort result in a small number of muscle synergies during gait

(2014) Friedl De Groote et al.   Frontiers in Computational Neuroscience

Sensory feedback to ankle plantar flexors is not exaggerated during gait in spastic hemiplegic children with cerebral palsy

(2013) Maria Willerslev-Olsen et al.   JOURNAL OF NEUROPHYSIOLOGY

A real-time system for biomechanical analysis of human movement and muscle function

(2013) Antonie J. van den Bogert et al.   MEDICAL & BIOLOGICAL ENGINEERING & COMPUTING

How robust is human gait to muscle weakness?

(2012) Marjolein M. van der Krogt et al.   GAIT & POSTURE

A clinical measurement to quantify spasticity in children with cerebral palsy by integration of multidimensional signals

(2012) L. Bar-On et al.   GAIT & POSTURE

Medial gastrocnemius muscle fascicle active torque-length and Achilles tendon properties in young adults with spastic cerebral palsy

(2012) Lee Barber et al.   JOURNAL OF BIOMECHANICS

Single-event multilevel surgery for children with cerebral palsy: a systematic review

(2011) JENNIFER L MCGINLEY et al.   DEVELOPMENTAL MEDICINE AND CHILD NEUROLOGY

Medial gastrocnemius muscle volume and fascicle length in children aged 2 to 5 years with cerebral palsy

(2011) LEE BARBER et al.   DEVELOPMENTAL MEDICINE AND CHILD NEUROLOGY

Calculating gait kinematics using MR-based kinematic models

(2011) Lennart Scheys et al.   GAIT & POSTURE

Muscle paresis and passive stiffness: Key determinants in limiting function in Hereditary and Sporadic Spastic Paraparesis

(2011) Jon Marsden et al.   GAIT & POSTURE

Passive muscle mechanical properties of the medial gastrocnemius in young adults with spastic cerebral palsy

(2011) Lee Barber et al.   JOURNAL OF BIOMECHANICS

Level of subject-specific detail in musculoskeletal models affects hip moment arm length calculation during gait in pediatric subjects with increased femoral anteversion

(2011) Lennart Scheys et al.   JOURNAL OF BIOMECHANICS

Hamstring contractures in children with spastic cerebral palsy result from a stiffer extracellular matrix and increasedin vivosarcomere length

(2011) Lucas R. Smith et al.   JOURNAL OF PHYSIOLOGY-LONDON

Gross muscle morphology and structure in spastic cerebral palsy: a systematic review

(2010) ROD S BARRETT et al.   DEVELOPMENTAL MEDICINE AND CHILD NEUROLOGY

Sensitivity of dynamic simulations of gait and dynamometer experiments to hill muscle model parameters of knee flexors and extensors

(2010) F. De Groote et al.   JOURNAL OF BIOMECHANICS

The use of botulinum toxin A in children with cerebral palsy, with a focus on the lower limb

(2010) Guy Molenaers et al.   Journal of Childrens Orthopaedics

A physiology based inverse dynamic analysis of human gait: potential and perspectives

(2009) F. De Groote et al.   COMPUTER METHODS IN BIOMECHANICS AND BIOMEDICAL ENGINEERING

Atlas-based non-rigid image registration to automatically define line-of-action muscle models: A validation study

(2009) Lennart Scheys et al.   JOURNAL OF BIOMECHANICS

Are the recommendations from three-dimensional gait analysis associated with better postoperative outcomes in patients with cerebral palsy?

(2008) Mauro César de Morais Filho et al.   GAIT & POSTURE

Personalized MR-based musculoskeletal models compared to rescaled generic models in the presence of increased femoral anteversion: Effect on hip moment arm lengths

(2008) Lennart Scheys et al.   GAIT & POSTURE