Serine is required for the maintenance of redox balance and proliferation in the intestine under oxidative stress

Serine prevented high-fat diet-induced oxidative stress by activating AMPK and epigenetically modulating the expression of glutathione synthesis-related genes

(2018) Xihong Zhou et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Serine Catabolism by SHMT2 Is Required for Proper Mitochondrial Translation Initiation and Maintenance of Formylmethionyl-tRNAs

(2018) Denise R. Minton et al.   MOLECULAR CELL

Disruption of De Novo Serine Synthesis in Müller Cells Induced Mitochondrial Dysfunction and Aggravated Oxidative Damage

(2018) Ting Zhang et al.   MOLECULAR NEUROBIOLOGY

Serine Availability Influences Mitochondrial Dynamics and Function through Lipid Metabolism

(2018) Xia Gao et al.   Cell Reports

Prevention of Oxidative Stress by α-Ketoglutarate via Activation of CAR Signaling and Modulation of the Expression of Key Antioxidant-Associated Targets in Vivo and in Vitro

(2018) Liuqin He et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Serine Alleviates Dextran Sulfate Sodium-Induced Colitis and Regulates the Gut Microbiota in Mice

(2018) Haiwen Zhang et al.   Frontiers in Microbiology

Serine alleviates oxidative stress via supporting glutathione synthesis and methionine cycle in mice

(2017) Xihong Zhou et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Serine prevents LPS-induced intestinal inflammation and barrier damage via p53-dependent glutathione synthesis and AMPK activation

(2017) Xihong Zhou et al.   Journal of Functional Foods

The CASTOR Proteins Are Arginine Sensors for the mTORC1 Pathway

(2016) Lynne Chantranupong et al.   CELL

Chasing One-Carbon Units to Understand the Role of Serine in Epigenetics

(2016) Seth J. Parker et al.   MOLECULAR CELL

A PHGDH inhibitor reveals coordination of serine synthesis and one-carbon unit fate

(2016) Michael E Pacold et al.   Nature Chemical Biology

Sestrin2 is a leucine sensor for the mTORC1 pathway

(2015) R. L. Wolfson et al.   SCIENCE

The combination of ursolic acid and leucine potentiates the differentiation of C2C12 murine myoblasts through the mTOR signaling pathway

(2014) MINJUNG KIM et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Selenium-enriched exopolysaccharides improve skeletal muscle glucose uptake of diabetic KKAy mice via AMPK pathway

(2014) Xihong Zhou et al.   JOURNAL OF PHYSIOLOGY AND BIOCHEMISTRY

Oxidative Stress: An Essential Factor in the Pathogenesis of Gastrointestinal Mucosal Diseases

(2014) Asima Bhattacharyya et al.   PHYSIOLOGICAL REVIEWS

Characterization of the Usage of the Serine Metabolic Network in Human Cancer

(2014) Mahya Mehrmohamadi et al.   Cell Reports

Structural basis of AMPK regulation by small molecule activators

(2013) Bing Xiao et al.   Nature Communications

A genome-wide detection of copy number variations using SNP genotyping arrays in swine

(2012) Jiying Wang et al.   BMC GENOMICS

Serine starvation induces stress and p53-dependent metabolic remodelling in cancer cells

(2012) Oliver D. K. Maddocks et al.   NATURE

Intestinal redox biology and oxidative stress

(2012) Magdalena L. Circu et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Arginine-induced stimulation of protein synthesis and survival in IPEC-J2 cells is mediated by mTOR but not nitric oxide

(2010) Caroline Bauchart-Thevret et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Cell Cycle Arrest Induced by Hydrogen Peroxide Is Associated with Modulation of Oxidative Stress Related Genes in Breast Cancer Cells

(2009) Pei-Jou Chua et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Nrf2:INrf2 (Keap1) signaling in oxidative stress

(2009) James W. Kaspar et al.   FREE RADICAL BIOLOGY AND MEDICINE

Optimization and application of glutamate cysteine ligase measurement in wildlife species

(2008) Hongmei Wu et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY