Neutrophil-derived advanced glycation end products-Nε-(carboxymethyl) lysine promotes RIP3-mediated myocardial necroptosis via RAGE and exacerbates myocardial ischemia/reperfusion injury

Advanced glycation end-products produced systemically and by macrophages: A common contributor to inflammation and degenerative diseases

(2017) Kyunghee Byun et al.   PHARMACOLOGY & THERAPEUTICS

The spleen contributes importantly to myocardial infarct exacerbation during post-ischemic reperfusion in mice via signaling between cardiac HMGB1 and splenic RAGE

(2016) Yikui Tian et al.   BASIC RESEARCH IN CARDIOLOGY

Loss of Glyoxalase 1 Induces Compensatory Mechanism to Achieve Dicarbonyl Detoxification in Mammalian Schwann Cells

(2016) Jakob Morgenstern et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

CaMKII is a RIP3 substrate mediating ischemia- and oxidative stress–induced myocardial necroptosis

(2016) Ting Zhang et al.   NATURE MEDICINE

Protein-Bound Plasma Nε-(Carboxymethyl)lysine Is Inversely Associated With Central Obesity and Inflammation and Significantly Explain a Part of the Central Obesity–Related Increase in InflammationSignificance

(2015) Katrien H.J. Gaens et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

The role of methylglyoxal and the glyoxalase system in diabetes and other age-related diseases

(2015) Dionne E.M. Maessen et al.   CLINICAL SCIENCE

Depletion of PHD3 protects heart from ischemia/reperfusion injury by inhibiting cardiomyocyte apoptosis

(2015) Liang Xie et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Pathophysiology Underlying the Bimodal Edema Phenomenon After Myocardial Ischemia/Reperfusion

(2015) Rodrigo Fernández-Jiménez et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Evolving Therapies for Myocardial Ischemia/Reperfusion Injury

(2015) Borja Ibáñez et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Mechanical Pre-Conditioning With Acute Circulatory Support Before Reperfusion Limits Infarct Size in Acute Myocardial Infarction

(2015) Navin K. Kapur et al.   JACC-Heart Failure

RIP3, a kinase promoting necroptotic cell death, mediates adverse remodelling after myocardial infarction

(2014) Mark Luedde et al.   CARDIOVASCULAR RESEARCH

Crosstalk between Sentinel and Helper Macrophages Permits Neutrophil Migration into Infected Uroepithelium

(2014) Marzena Schiwon et al.   CELL

Macrophages are required for neonatal heart regeneration

(2014) Arin B. Aurora et al.   JOURNAL OF CLINICAL INVESTIGATION

Temporal dynamics of cardiac immune cell accumulation following acute myocardial infarction

(2013) Xiaoxiang Yan et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

ACCF/AHA/ASE/ASNC/HFSA/HRS/SCAI/SCCT/SCMR/STS 2013 Multimodality Appropriate Use Criteria for the Detection and Risk Assessment of Stable Ischemic Heart Disease

(2013) Michael J. Wolk et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Diagnosis and Management of Ischemic Heart Disease

(2013) Massimo Franchini et al.   SEMINARS IN THROMBOSIS AND HEMOSTASIS

Depletion of neutrophils in a protective model of pulmonary cryptococcosis results in increased IL-17A production by gamma/delta T cells

(2012) Karen L Wozniak et al.   BMC IMMUNOLOGY

Mixed Lineage Kinase Domain-like Protein Mediates Necrosis Signaling Downstream of RIP3 Kinase

(2012) Liming Sun et al.   CELL

Resveratrol Upregulates Nrf2 Expression To Attenuate Methylglyoxal-Induced Insulin Resistance in Hep G2 Cells

(2012) An-Sheng Cheng et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Endogenous formation of Nε-(carboxymethyl)lysine is increased in fatty livers and induces inflammatory markers in an in vitro model of hepatic steatosis

(2011) Katrien H.J. Gaens et al.   JOURNAL OF HEPATOLOGY

Fisetin Lowers Methylglyoxal Dependent Protein Glycation and Limits the Complications of Diabetes

(2011) Pamela Maher et al.   PLoS One

Candesartan Attenuates Diabetic Retinal Vascular Pathology by Restoring Glyoxalase-I Function

(2010) A. G. Miller et al.   DIABETES

RAGE Modulates Hypoxia/Reoxygenation Injury in Adult Murine Cardiomyocytes via JNK and GSK-3β Signaling Pathways

(2010) Linshan Shang et al.   PLoS One

Phosphorylation-Driven Assembly of the RIP1-RIP3 Complex Regulates Programmed Necrosis and Virus-Induced Inflammation

(2009) YoungSik Cho et al.   CELL

Receptor Interacting Protein Kinase-3 Determines Cellular Necrotic Response to TNF-α

(2009) Sudan He et al.   CELL

Elevation of the glycoxidation product Nε-(carboxymethyl)lysine in patients presenting with acute myocardial infarction

(2009) Stefan Kralev et al.   CLINICAL CHEMISTRY AND LABORATORY MEDICINE

High-Mobility Group Box-1 in Ischemia-Reperfusion Injury of the Heart

(2008) Martin Andrassy et al.   CIRCULATION

An improved protocol for primary culture of cardiomyocyte from neonatal mice

(2008) P. Sreejit et al.   IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY-ANIMAL