Journal
EUROPEAN RADIOLOGY
Volume 30, Issue 3, Pages 1488-1497Publisher
SPRINGER
DOI: 10.1007/s00330-019-06540-x
Keywords
Magnetic resonance imaging; Cone-beam computed tomography; Orthodontics; Orthognathic surgery; Oral and maxillofacial surgeons
Funding
- Dietmar Hopp Foundation [23011228]
- Medical Faculty of the University of Heidelberg
Ask authors/readers for more resources
Objectives To evaluate whether magnetic resonance imaging (MRI) can serve as an alternative diagnostic tool to the gold standard cone-beam computed tomography (CBCT) in 3D cephalometric analysis. Methods In this prospective feasibility study, 12 patients (8 males, 4 females; mean age +/- SD, 26.1 years +/- 6.6) underwent 3D MRI and CBCT before orthognathic surgery. 3D cephalometric analysis was performed twice by two independent observers on both modalities. For each dataset, 27 cephalometric landmarks were defined from which 35 measurements (17 angles, 18 distances) were calculated. Statistical analyses included the calculation of Euclidean distances, intraclass correlation coefficients (ICCs), Bland-Altman analysis, and equivalence testing (linear mixed effects model) with a predefined equivalence margin of +/- 1 degrees/1 mm. Results Analysis of reliability for CBCT vs. MRI (intra-rater I/intra-rater II/inter-rater) revealed Euclidean distances of 0.86/0.86/0.98 mm vs. 0.93/0.99/1.10 mm for landmarks, ICCs of 0.990/0.980/0.986 vs. 0.982/0.978/0.980 for angles, and ICCs of 0.992/0.988/0.989 vs. 0.991/0.985/0.988 for distances. Bland-Altman analysis showed high levels of agreement between CBCT and MRI with bias values (95% levels of agreement) of 0.03 degrees (- 1.49; 1.54) for angles and 0.02 mm (- 1.44; 1.47) for distances. In the linear mixed effects model, the mean values of CBCT and MRI measurements were equivalent. Conclusion This feasibility study indicates that MRI enables reliable 3D cephalometric analysis with excellent agreement to corresponding measurements on CBCT. Thus, MRI could serve as a non-ionizing alternative to CBCT for treatment planning and monitoring in orthodontics as well as oral and maxillofacial surgery.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available