Promoter hypermethylation of PIWI/piRNA pathway genes associated with diminished pachytene piRNA production in bovine hybrid male sterility

Comparison of Y-chromosome-linked TSPY, TSPY2, and PRAMEY genes in Taurus cattle, yaks, and interspecific hybrid bulls

(2019) Gong-Wei Zhang et al.   JOURNAL OF DAIRY SCIENCE

TDRD5 binds piRNA precursors and selectively enhances pachytene piRNA processing in mice

(2018) Deqiang Ding et al.   Nature Communications

Single-Cell RNA Sequencing Analysis Reveals Sequential Cell Fate Transition during Human Spermatogenesis

(2018) Mei Wang et al.   Cell Stem Cell

Exonuclease Domain-Containing 1 Enhances MIWI2 piRNA Biogenesis via Its Interaction with TDRD12

(2018) Radha Raman Pandey et al.   Cell Reports

PIWI-interacting RNAs: small RNAs with big functions

(2018) Deniz M. Ozata et al.   NATURE REVIEWS GENETICS

piRBase: a comprehensive database of piRNA sequences

(2018) Jiajia Wang et al.   NUCLEIC ACIDS RESEARCH

Mitochondrial membrane-based initial separation of MIWI and MILI functions during pachytene piRNA biogenesis

(2018) Deqiang Ding et al.   NUCLEIC ACIDS RESEARCH

Two modes of targeting transposable elements by piRNA pathway in human testis

(2017) Ildar Gainetdinov et al.   RNA

Comparative analysis of testis transcriptomes associated with male infertility in cattleyak

(2017) Xin Cai et al.   THERIOGENOLOGY

PNLDC1 is essential for piRNA 3′ end trimming and transposon silencing during spermatogenesis in mice

(2017) Deqiang Ding et al.   Nature Communications

Transcriptome analysis of highly purified mouse spermatogenic cell populations: gene expression signatures switch from meiotic-to postmeiotic-related processes at pachytene stage

(2016) Irene da Cruz et al.   BMC GENOMICS

Misregulation of Gene Expression and Sterility in Interspecies Hybrids: Causal Links and Alternative Hypotheses

(2016) Alberto Civetta   JOURNAL OF MOLECULAR EVOLUTION

Comparative iTRAQ proteomics revealed proteins associated with spermatogenic arrest of cattleyak

(2016) Shumin Yu et al.   Journal of Proteomics

Re-engineering the zinc fingers of PRDM9 reverses hybrid sterility in mice

(2016) Benjamin Davies et al.   NATURE

Differential DNA methylation of the meiosis-specific geneFKBP6in testes of yak and cattle-yak hybrids

(2016) B Li et al.   REPRODUCTION IN DOMESTIC ANIMALS

Establishment and functions of DNA methylation in the germline

(2016) Kathleen R Stewart et al.   Epigenomics

Abnormal Hypermethylation of the VDAC2 Promoter is a Potential Cause of Idiopathic Asthenospermia in Men

(2016) Aiming Xu et al.   Scientific Reports

PIWI-Interacting RNA: Its Biogenesis and Functions

(2015) Yuka W. Iwasaki et al.   Annual Review of Biochemistry

MIWI and piRNA-mediated cleavage of messenger RNAs in mouse testes

(2015) Peng Zhang et al.   CELL RESEARCH

RNF17 blocks promiscuous activity of PIWI proteins in mouse testes

(2015) Kaja A. Wasik et al.   GENES & DEVELOPMENT

The RNA helicase MOV10L1 binds piRNA precursors to initiate piRNA processing

(2015) Anastassios Vourekas et al.   GENES & DEVELOPMENT

piRNA-directed cleavage of meiotic transcripts regulates spermatogenesis

(2015) Wee Siong Sho Goh et al.   GENES & DEVELOPMENT

MIWI2 and MILI Have Differential Effects on piRNA Biogenesis and DNA Methylation

(2015) Sergei A. Manakov et al.   Cell Reports

HENMT1 and piRNA Stability Are Required for Adult Male Germ Cell Transposon Repression and to Define the Spermatogenic Program in the Mouse

(2015) Shu Ly Lim et al.   PLoS Genetics

Pachytene piRNAs instruct massive mRNA elimination during late spermiogenesis

(2014) Lan-Tao Gou et al.   CELL RESEARCH

Reduced pachytene piRNAs and translation underlie spermiogenic arrest in Maelstrom mutant mice

(2014) J. Castaneda et al.   EMBO JOURNAL

piRNA pathway targets active LINE1 elements to establish the repressive H3K9me3 mark in germ cells

(2014) D. Pezic et al.   GENES & DEVELOPMENT

The low expression of Dmrt7 is associated with spermatogenic arrest in cattle-yak

(2014) Ping Yan et al.   MOLECULAR BIOLOGY REPORTS

A Bayesian hierarchical model to detect differentially methylated loci from single nucleotide resolution sequencing data

(2014) Hao Feng et al.   NUCLEIC ACIDS RESEARCH

Regulation of spermatogenesis by small non-coding RNAs: Role of the germ granule

(2014) Sara de Mateo et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Molecular cloning, gene expression and methylation status analysis of PIWIL1 in cattle-yaks and the parental generation

(2013) Yao Gu et al.   ANIMAL REPRODUCTION SCIENCE

Splice variants and promoter methylation status of the Bovine Vasa Homology (Bvh) gene may be involved in bull spermatogenesis

(2013) Hua Luo et al.   BMC GENETICS

Defining piRNA primary transcripts

(2013) Xin Zhiguo Li et al.   CELL CYCLE

Epigenetic loss of the PIWI/piRNA machinery in human testicular tumorigenesis

(2013) Humberto J Ferreira et al.   Epigenetics

Histological evaluation and Prdm9 expression level in the testis of sterile male cattle-yaks

(2013) Y.N. Lou et al.   Livestock Science

Multiple Epigenetic Mechanisms and the piRNA Pathway Enforce LINE1 Silencing during Adult Spermatogenesis

(2013) Monica Di Giacomo et al.   MOLECULAR CELL

An Ancient Transcription Factor Initiates the Burst of piRNA Production during Early Meiosis in Mouse Testes

(2013) Xin Zhiguo Li et al.   MOLECULAR CELL

Tudor domain containing 12 (TDRD12) is essential for secondary PIWI interacting RNA biogenesis in mice

(2013) R. R. Pandey et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Roles for the lipid-signaling enzyme MitoPLD in mitochondrial dynamics, piRNA biogenesis, and spermatogenesis

(2012) Qun Gao et al.   BMB Reports

Biology of PIWI-interacting RNAs: new insights into biogenesis and function inside and outside of germlines

(2012) H. Ishizu et al.   GENES & DEVELOPMENT

A Role for Fkbp6 and the Chaperone Machinery in piRNA Amplification and Transposon Silencing

(2012) Jordi Xiol et al.   MOLECULAR CELL

The yak genome and adaptation to life at high altitude

(2012) Qiang Qiu et al.   NATURE GENETICS

Fast gapped-read alignment with Bowtie 2

(2012) Ben Langmead et al.   NATURE METHODS

Functions of DNA methylation: islands, start sites, gene bodies and beyond

(2012) Peter A. Jones   NATURE REVIEWS GENETICS

Mili and Miwi target RNA repertoire reveals piRNA biogenesis and function of Miwi in spermiogenesis

(2012) Anastassios Vourekas et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Epigenetic Disruption of the PIWI Pathway in Human Spermatogenic Disorders

(2012) Holger Heyn et al.   PLoS One

Comparative analysis on mRNA expression level and methylation status of DAZL gene between cattle-yaks and their parents

(2011) Zhenshan Liu et al.   ANIMAL REPRODUCTION SCIENCE

The Genetics of Hybrid Incompatibilities

(2011) Shamoni Maheshwari et al.   Annual Review of Genetics

A k-mer scheme to predict piRNAs and characterize locust piRNAs

(2011) Yi Zhang et al.   BIOINFORMATICS

Bismark: a flexible aligner and methylation caller for Bisulfite-Seq applications

(2011) Felix Krueger et al.   BIOINFORMATICS

Epigenetics, spermatogenesis and male infertility

(2011) Singh Rajender et al.   MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH

Miwi catalysis is required for piRNA amplification-independent LINE1 transposon silencing

(2011) Michael Reuter et al.   NATURE

Differential mRNA Expression and Promoter Methylation Status of SYCP3 Gene in Testes of Yaks and Cattle-Yaks

(2011) S Wang et al.   REPRODUCTION IN DOMESTIC ANIMALS

piRNA profiling during specific stages of mouse spermatogenesis

(2011) H. Gan et al.   RNA

MVH in piRNA processing and gene silencing of retrotransposons

(2010) S. Kuramochi-Miyagawa et al.   GENES & DEVELOPMENT

Mouse MOV10L1 associates with Piwi proteins and is an essential component of the Piwi-interacting RNA (piRNA) pathway

(2010) K. Zheng et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Differential expression analysis for sequence count data

(2010) Simon Anders et al.   GENOME BIOLOGY

Mili Interacts with Tudor Domain-Containing Protein 1 in Regulating Spermatogenesis

(2009) Jianquan Wang et al.   CURRENT BIOLOGY

A Broadly Conserved Pathway Generates 3′UTR-Directed Primary piRNAs

(2009) Nicolas Robine et al.   CURRENT BIOLOGY

MTHFR promoter hypermethylation in testicular biopsies of patients with non-obstructive azoospermia: the role of epigenetics in male infertility

(2009) N. Khazamipour et al.   HUMAN REPRODUCTION

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

(2009) Da Wei Huang et al.   Nature Protocols

Loss of the Mili-interacting Tudor domain–containing protein-1 activates transposons and alters the Mili-associated small RNA profile

(2009) Michael Reuter et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Ultrafast and memory-efficient alignment of short DNA sequences to the human genome

(2009) Ben Langmead et al.   GENOME BIOLOGY

DNA methylation of retrotransposon genes is regulated by Piwi family members MILI and MIWI2 in murine fetal testes

(2008) S. Kuramochi-Miyagawa et al.   GENES & DEVELOPMENT

Epigenetic, transposon and small RNA determinants of hybrid dysfunctions

(2008) P Michalak   HEREDITY

A piRNA Pathway Primed by Individual Transposons Is Linked to De Novo DNA Methylation in Mice

(2008) Alexei A. Aravin et al.   MOLECULAR CELL

A Mouse Speciation Gene Encodes a Meiotic Histone H3 Methyltransferase

(2008) O. Mihola et al.   SCIENCE