Article
Medicine, General & Internal
Timothy L. Pruett, Gabriel R. Vece, Robert J. Carrico, David K. Klassen
Summary: Despite a shortage of kidney supply in the US, kidneys from older deceased donors are underutilized due to concerns about graft quality and transplant durability. However, the study found that one-year graft survival does not significantly differ based on donor age, with the primary factor affecting longevity being the level of kidney function gained post-transplantation. Effective decision-making tools are needed to ensure transplanting older kidneys provides sufficient renal function to justify the procedure.
Article
Urology & Nephrology
Hakeem Edun Babatunde, Afeez Oyesola Bello, Muhammed A. Nurudeen Adeboye, Olumuyiwa Shola Folayan, Olugoke Ezekiel Ojewole, Usman Abubakar
Summary: This study compared the cystatin C-derived estimated glomerular filtration rate (GFR) between children with sickle cell anemia (SCA) and healthy controls, finding a significant difference. The prevalence of supernormal GFR and decreased GFR in children with SCA was reported, with no significant association between clinical features of chronic kidney disease (CKD) and decreased GFR in the SCA group. Regular renal evaluation is recommended for early detection and treatment of renal complications in children with SCA.
Article
Endocrinology & Metabolism
Yue Zhang, Wenxing Gao, Rui Ren, Yang Liu, Binqi Li, Anping Wang, Xulei Tang, Li Yan, Zuojie Luo, Guijun Qin, Lulu Chen, Qin Wan, Zhengnan Gao, Weiqing Wang, Guang Ning, Yiming Mu
Summary: This study aims to assess the relationship between estimated glomerular filtration rate (eGFR) and body roundness index (BRI) among the Chinese population. The results show a positive correlation between BRI and low eGFR, suggesting that BRI can be an effective indicator for screening high-risk groups for kidney disease.
FRONTIERS IN ENDOCRINOLOGY
(2023)
Article
Gastroenterology & Hepatology
Carlos Gonzalez-Alayon, Esteban Porrini, Sergio Luis-Lima, Natalia Negrin-Mena, Miguel Moreno, Dalia Morales-Arraez, Federico Gonzalez-Rinne, Laura Diaz-Martin, Flavio Gaspari, Alejandra Gonzalez-Delgado, Carmen Ferrer-Moure, Alberto Ortiz-Arduan, Manuel Hernandez-Guerra
Summary: In patients with cirrhosis, formulas for estimating renal function, whether specific to this population or classic equations, have not been proven to be reliable. The study found poor agreement between estimated and measured glomerular filtration rate in cirrhotic patients, indicating caution should be exercised when using eGFR in this population.
LIVER INTERNATIONAL
(2022)
Article
Environmental Sciences
Nan Zhao, Xinxin Fang, Shiwen Zhang, Yuting Zhu, Lei Ding, Caihong Xu
Summary: This study found that male serum total short-chain CP and medium-chain CP concentrations were associated with kidney function, specifically with elevated risk of glomerular hyperfiltration (GH), while no such associations were observed in females.
ENVIRONMENT INTERNATIONAL
(2021)
Article
Multidisciplinary Sciences
Max Taubert, Elke Schaeffner, Peter Martus, Markus van der Giet, Uwe Fuhr, Amina Loesment, Natalie Ebert
Summary: In this study, the impact of a Bayesian estimation procedure on iohexol clearance estimates was evaluated, and an optimal sampling strategy was identified based on data in individuals aged 70+. A simplified three-compartment model was found to be optimal for estimating iohexol clearance in elderly patients with reduced GFR.
SCIENTIFIC REPORTS
(2021)
Article
Surgery
Melanie P. Hoenig, Alison Mann, Martha Pavlakis
Summary: This single-center initiative demonstrates the benefits of discarding race from the eGFR report for Black patients awaiting kidney transplantation, leading to an increase in listed Black patients and a reduction in disparities in access to kidney transplants.
CLINICAL TRANSPLANTATION
(2022)
Review
Medicine, General & Internal
Irene L. Noronha, Guilherme P. Santa-Catharina, Lucia Andrade, Venceslau A. Coelho, Wilson Jacob-Filho, Rosilene M. Elias
Summary: Improvements in life expectancy have led to an increase in the elderly population and a higher prevalence of non-communicable diseases. As the kidney is commonly affected by various diseases, evaluating renal function in the older population is crucial. Aging results in structural and functional changes in the kidneys, leading to declined glomerular filtration rate. Accurately assessing renal function in the elderly is important for tailored therapeutic interventions.
FRONTIERS IN MEDICINE
(2022)
Letter
Medicine, General & Internal
Jonathan R. Genzen, Rhona J. Souers, Lauren N. Pearson, David M. Manthei, Allison B. Chambliss, Zahra Shajani-Yi, W. Greg Miller
Summary: This study examines the awareness and adoption of new equations for estimated glomerular filtration rate (eGFR) in clinical laboratories that participated in the first general chemistry proficiency testing survey in 2022. The new equations, proposed by the Chronic Kidney Disease Epidemiology Collaboration, eliminate race-adjustment factors and include equations based on creatinine alone or a combination of creatinine and cystatin C.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
(2022)
Article
Pharmacology & Pharmacy
Tom C. Zwart, Aiko P. J. de Vries, Aline G. J. Engbers, Ruth E. Dam, Paul J. M. van der Boog, Jesse J. Swen, Ron J. Keizer, R. Neil Dalton, Henk-Jan Guchelaar, Johan W. de Fijter, Dirk Jan A. R. Moes
Summary: Iohexol plasma clearance-based glomerular filtration rate determination is an accurate method for renal function evaluation, especially in renal transplantation. The study demonstrates the feasibility and accuracy of an experimental method based on limited sampling and pharmacokinetic modeling in clinical practice.
CLINICAL PHARMACOKINETICS
(2021)
Article
Immunology
Pierre Delanaye, Ingrid Masson, Nicolas Maillard, Hans Pottel, Christophe Mariat
Summary: This study compared the predictive performance of the new CKD-EPI equation, classical CKD-EPI equation, and EKFC equation in a French cohort of KTRs. The results showed that the new CKD-EPI equation was less accurate compared to the classical CKD-EPI and EKFC equations. Further validation of the EKFC equation in KTRs with diverse ethnic backgrounds is needed.
Article
Medicine, General & Internal
Elisabet Van Loon, Wanqiu Zhang, Maarten Coemans, Maarten De Vos, Marie-Paule Emonds, Irina Scheffner, Wilfried Gwinner, Dirk Kuypers, Aleksandar Senev, Claire Tinel, Amaryllis H. Van Craenenbroeck, Bart De Moor, Maarten Naesens
Summary: A deep learning model was developed and validated to predict the patient-specific expected reference range of eGFR after kidney transplant, showing promising results in accurately forecasting individual trajectories within the first 3 months post-transplant.
Article
Environmental Sciences
Habyeong Kang, Jung Pyo Lee, Kyungho Choi
Summary: Exposure to consumer chemicals has been found to have inconsistent associations with estimated glomerular filtration rate (eGFR) when adjusted by different methods, but novel covariate-adjusted creatinine standardization revealed significant inverse associations. Phthalate metabolites, DEHP, and BPA were identified as major drivers of the association with eGFR or ACR in mixture exposure models using weighted quantile sum regression. The study suggests that exposure to specific chemicals may lead to declined eGFR and increased ACR in the general adult population.
SCIENCE OF THE TOTAL ENVIRONMENT
(2021)
Article
Medicine, General & Internal
Si-Qi Liu, Xiu-Jun Zhang, Yuan Xue, Rui Huang, Jian Wang, Chao Wu, Yi-Shan He, Ya-Ru Pan, Long-Gen Liu
Summary: This study found that dynamic changes in renal function were inversely related to triglyceride (TG) levels during TDF treatment in patients with chronic hepatitis B (CHB) and normal body mass index, while no significant correlation was observed in overweight patients.
WORLD JOURNAL OF CLINICAL CASES
(2022)
Article
Urology & Nephrology
Veronica T. Costa e Silva, Luiz A. Gil Jr, Lesley A. Inker, Renato A. Caires, Elerson Costalonga, George Coura-Filho, Marcelo T. Sapienza, Gilberto Castro Jr, Maria Dp Estevez-Diz, Dirce Maria T. Zanetta, Leila Antonangelo, Lia Marcal, Hocine Tighiouart, Shiyuan Miao, Paul Mathew, Andrew S. Levey, Emmanuel A. Burdmann
Summary: This study compares the performance of different equations for glomerular filtration rate (GFR) evaluation in cancer patients. The results show that the Cockcroft-Gault equation is the least accurate, while the CKD-EPI equation and eGFRcr-cys equation perform better. Therefore, it is recommended to adopt guideline-recommended methods for GFR evaluation in oncology practice and clinical trials.
KIDNEY INTERNATIONAL
(2022)
Article
Environmental Sciences
Cheng Fang, Yunlong Luo, Xian Zhang, Hongping Zhang, Annette Nolan, Ravi Naidu
Summary: This study compares two decoding approaches for visualising microplastics and nanoplastics via Raman imaging. The first approach maps Raman intensity at characteristic peaks when standard spectra are available, while the second approach uses PCA to decode the spectrum matrix for complex samples without standard spectra. The PCA-based algorithm shows advantages in analysing and identifying microplastics from other materials.
Article
Environmental Sciences
Yongliang Chen, Masud Hassan, Md Nuruzzaman, Huiming Zhang, Ravi Naidu, Yanju Liu, Ling Wang
Summary: Adsorption is a promising remediation technology for separating organic and inorganic agrochemicals from contaminated soil and water. This study focuses on the use of iron-modified base-activated biochar (FeBBC) as a low-cost adsorbent for removing the insecticide imidacloprid from water. The FeBBC exhibits high adsorption capacity and both physical and chemical interactions contribute to the sorption process. The results demonstrate the potential of FeBBC as an effective adsorbent for removing organic contaminants.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2023)
Article
Agronomy
Solmaz Bidast, Ahmad Golchin, Ahmad Baybordi, Amir Mohseni, Ravi Naidu
Summary: The potential of bare and carboxymethyl cellulose (CMC)-coated iron oxide nanoparticles (FeONPs) for stabilising lead (Pb), zinc (Zn), and cadmium (Cd) in contaminated soil was investigated. The results showed that CMC-coated FeONPs were more effective in decreasing the availability of potentially toxic elements in the soil. CMC-coated goethite was the most effective treatment for reducing Zn and Cd availability, while CMC-coated magnetite was the most effective for Pb stabilisation.
ARCHIVES OF AGRONOMY AND SOIL SCIENCE
(2023)
Article
Environmental Sciences
M. A. A. Wijayawardena, K. Yan, Y. Liu, R. Naidu
Summary: Mouse models have been commonly used to predict the bioavailability of metals and chemicals in humans. In this study, the effectiveness of mouse models in predicting the bioavailability of lead in metal mixtures was confirmed, while their ability to predict the bioavailability of arsenic was found to be limited.
Article
Environmental Sciences
Sara Ghavamifar, Ravi Naidu, Vahid Mozafari, Zhaohui Li
Summary: In this study, two sorbents, calcite and saponite, were used to investigate their capacity to sorb glyphosate. It was found that the morphology of calcite transformed and the zeta potential became positive in alkaline pH, contradicting previous research. The modified sorbents were added to soil samples to study their effects on glyphosate sorption.
Article
Environmental Sciences
Yunlong Luo, Ravi Naidu, Cheng Fang
Summary: This study investigates the surface functional group changes and release of microplastics and nanoplastics during the combustion process of an outdoor plastic chair. Scanning electron microscopy (SEM) and Raman imaging techniques are used to characterize the fragments created when the plastic is burned and deposited on solid surfaces. Different algorithms, including logic-based, non-supervised PCA-based, algebra-based, and hybrid algorithms, are tested and optimized to extract key information for plastics characterization, particularly in distinguishing different degrees of burning. The findings estimate that tens of microplastics and nanoplastics are created per square micron during the combustion process.
ENVIRONMENTAL POLLUTION
(2023)
Article
Environmental Sciences
Matthew Dietrich, Cynthia F. Barlow, Jane A. Entwistle, Diana Meza-Figueroa, Chenyin Dong, Peggy Gunkel-Grillon, Khadija Jabeen, Lindsay Bramwell, John T. Shukle, Leah R. Wood, Ravi Naidu, Kara Fry, Mark Patrick Taylor, Gabriel M. Filippelli
Summary: Lead (Pb) contamination continues to pose health risks in all countries, especially low-and middle-income countries. Predicting elevated household dust Pb levels and the potential impact of low-cost interventions has been a challenge. A global dataset of household dust samples was used to predict elevated dust Pb levels, with housing age being a significant predictor. The predictive accuracy of the model is lower for countries outside of England, the U.S., and Australia due to differences in regulations and data availability. Implementing simple household interventions in these countries could result in significant cost savings and reduced exposure to harmful Pb dust sources globally.
ENVIRONMENTAL POLLUTION
(2023)
Review
Environmental Sciences
Anwar Ul Haq Khan, Ravi Naidu, Raja Dharmarajan, Cheng Fang, Hokyong Shon, Zhaomin Dong, Yanju Liu
Summary: This review focuses on the occurrence and interactions of engineered nanoparticles (ENPs) and brominated flame retardants (BFRs) in water systems, as well as the formation of complex compounds in the environment. It summarizes the release of ENPs and BFRs, their key interaction mechanisms, and their influence on the behavior and toxic effects of PBDEs. The study highlights the distinct behavior of mixed compounds (ENPs-BFRs) and emphasizes the importance of understanding the interactions in comprehensive risk assessments.
JOURNAL OF ENVIRONMENTAL SCIENCES
(2023)
Article
Engineering, Environmental
Yunlong Luo, Ravi Naidu, Cheng Fang
Summary: Raman imaging can directly visualize the adsorption of perchlorate and allow real-time monitoring due to the low Raman activity and minimal interference of water. The enhancement of perchlorate's Raman signal on porous silver enables the monitoring of low-level adsorption.
Review
Fisheries
Nepheronia Jumalon Ogburn, Luchun Duan, Suresh Ramraj Subashchandrabose, Patrick Sorgeloos, Wayne O'Connor, Mallavarapu Megharaj, Ravi Naidu
Summary: Aquaculture, as one of the fastest growing food industry sectors, is facing sustainability challenges due to increasing global population and protein demand. The use of agricultural waste to produce Artemia, a kind of aquatic species, provides an environmentally sustainable solution for supporting aquaculture demand.
REVIEWS IN AQUACULTURE
(2023)
Article
Chemistry, Analytical
Md. Rashidul Islam, Peter Sanderson, Mathew P. Johansen, Timothy E. Payne, Ravi Naidu
Summary: This study evaluated the environmental behavior of beryllium in soil-water systems under different sorption conditions, and found that certain ions and factors such as temperature and concentration can affect the sorption and desorption of beryllium.
ENVIRONMENTAL SCIENCE-PROCESSES & IMPACTS
(2023)
Article
Environmental Sciences
Yunlong Luo, Ashkan Khoshyan, Md Al Amin, Annette Nolan, Fiona Robinson, Jim Fenstermacher, Junfeng Niu, Mallavarapu Megharaj, Ravi Naidu, Cheng Fang
Summary: In this study, a hybrid system combining electrochemical treatment with ultrasound irradiation is proposed for enhanced degradation of PFAS. The electrochemical process using a titanium suboxide anode effectively removes PFOA, and when combined with ultrasound irradiation, achieves 100% PFOA removal and 63.5% defluorination, indicating synergistic removal/oxidation effects.
SCIENCE OF THE TOTAL ENVIRONMENT
(2023)
Article
Environmental Sciences
Yunlong Luo, Ravi Naidu, Cheng Fang
Summary: The sources of microplastics and nanoplastics are widespread and include everyday activities. However, the limited techniques for characterization hinder the determination of their sources. We propose advancing Raman imaging by combining it with various algorithms to improve signal-noise ratio and imaging certainty, enabling the characterization of microplastics. We can capture and identify microplastics carried by smartphones, which are released from clothing and plastic decoration trinkets, accumulating on the phone surface or in ports. Further methodological improvements are necessary due to the complexity of the samples.
SCIENCE OF THE TOTAL ENVIRONMENT
(2023)
Article
Environmental Sciences
Aravind Unnithan, Dawit Nega Bekele, Sreenivasulu Chadalavada, Ravi Naidu
Summary: This study presents a 2-D model for chlorinated vapour intrusion, taking into account the role of highly permeable utility lines as a preferential pathway. The model's results are comparable to other models and show that the presence of highly permeable utility lines increases indoor air concentration.
SCIENCE OF THE TOTAL ENVIRONMENT
(2023)
Article
Environmental Sciences
Juan C. Sanchez-Hernandez, Cristobal Narvaez, Ximena Andrade Cares, Pablo Sabat, Ravi Naidu
Summary: Earthworms are being studied for their potential in bioremediation due to their impact on pollutant fate. Different earthworm species have varying sensitivities and capacities to break down contaminants, and Lumbricus terrestris is the most suitable species for bioremediation of OP-contaminated soil due to its higher levels of detoxification enzymes and oxidative homeostasis mechanisms compared to Eisenia fetida andAporrectodea caliginosa. These findings suggest L. terrestris as a better candidate for soil bioremediation than epigeic earthworms.
SCIENCE OF THE TOTAL ENVIRONMENT
(2023)