Dexmedetomidine May Reduce IL-6 Level and the Risk of Postoperative Cognitive Dysfunction in Patients After Surgery: A Meta-Analysis

A multicentre randomised controlled trial of the effect of intra-operative dexmedetomidine on cognitive decline after surgery

(2019) X.-Q. Cheng et al.   ANAESTHESIA

The role of general anesthetics and the mechanisms of hippocampal and extra-hippocampal dysfunctions in the genesis of postoperative cognitive dysfunction

(2017) Sabrina Bimonte et al.   Neural Regeneration Research

Microglia at center stage: a comprehensive review about the versatile and unique residential macrophages of the central nervous system

(2017) Nils Lannes et al.   Oncotarget

Effect of dexmedetomidine-induced anesthesia on the postoperative cognitive function of elder patients after laparoscopic ovarian cystectomy

(2017) Hui-ying Xu et al.   SAUDI JOURNAL OF BIOLOGICAL SCIENCES

Perioperative dexmedetomidine reduces the incidence and severity of acute kidney injury following valvular heart surgery

(2016) Jin Sun Cho et al.   KIDNEY INTERNATIONAL

Dexmedetomidine Protects against Transient Global Cerebral Ischemia/Reperfusion Induced Oxidative Stress and Inflammation in Diabetic Rats

(2016) Xianzhang Zeng et al.   PLoS One

S100A8 contributes to postoperative cognitive dysfunction in mice undergoing tibial fracture surgery by activating the TLR4/MyD88 pathway

(2015) Shun-Mei Lu et al.   BRAIN BEHAVIOR AND IMMUNITY

Meta-analysis in clinical trials revisited

(2015) Rebecca DerSimonian et al.   Contemporary Clinical Trials

Preferred reporting items for systematic review and meta-analysis protocols (PRISMA-P) 2015: elaboration and explanation

(2015) L. Shamseer et al.   BMJ-British Medical Journal

Preferred reporting items for systematic review and meta-analysis protocols (PRISMA-P) 2015: elaboration and explanation

(2015) L. Shamseer et al.   BMJ-British Medical Journal

The neuroinflammatory response of postoperative cognitive decline

(2013) S. Vacas et al.   BRITISH MEDICAL BULLETIN

Dexmedetomidine Reduced Cytokine Release during Postpartum Bleeding-Induced Multiple Organ Dysfunction Syndrome in Rats

(2013) Liu Xianbao et al.   MEDIATORS OF INFLAMMATION

Interleukin-6 and Memory Functions of Encoding and Recall in Healthy and Depressed Elderly Adults

(2012) Virginia Elderkin-Thompson et al.   AMERICAN JOURNAL OF GERIATRIC PSYCHIATRY

Analysis of Neuron-Specific Enolase and S100B as Biomarkers of Cognitive Decline Following Surgery in Older People

(2012) Emma L. Jones et al.   DEMENTIA AND GERIATRIC COGNITIVE DISORDERS

Dexmedetomidine may benefit cognitive function after laparoscopic cholecystectomy in elderly patients

(2012) JINGJUN CHEN et al.   Experimental and Therapeutic Medicine

Dexmedetomidine attenuates remote lung injury induced by renal ischemia-reperfusion in mice

(2011) J. GU et al.   ACTA ANAESTHESIOLOGICA SCANDINAVICA

Postoperative Cognitive Dysfunction Is Independent of Type of Surgery and Anesthetic

(2011) Lisbeth Evered et al.   ANESTHESIA AND ANALGESIA

Resolving postoperative neuroinflammation and cognitive decline

(2011) Niccolò Terrando et al.   ANNALS OF NEUROLOGY

Inhibition of interleukin-6 trans-signaling in the brain facilitates recovery from lipopolysaccharide-induced sickness behavior

(2011) Michael D Burton et al.   Journal of Neuroinflammation

The inhalation anesthetic isoflurane increases levels of proinflammatory TNF-α, IL-6, and IL-1β

(2010) Xu Wu et al.   NEUROBIOLOGY OF AGING

Predictors of Cognitive Dysfunction after Major Noncardiac Surgery

(2009) Terri G. Monk et al.   ANESTHESIOLOGY

Long-term Consequences of Postoperative Cognitive Dysfunction

(2009) Jacob Steinmetz et al.   ANESTHESIOLOGY

Dexmedetomidine: a review of clinical applications

(2009) Dominic S Carollo et al.   Current Opinion in Anesthesiology