PFKFB4 negatively regulated the expression of histone acetyltransferase GCN5 to mediate the tumorigenesis of thyroid cancer

Cancer statistics, 2019

(2019) Rebecca L. Siegel et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Analysis of Malignant Melanoma Cell Lines Exposed to Hypoxia Reveals the Importance of PFKFB4 Overexpression for Disease Progression

(2018) SONIA E. TROJAN et al.   ANTICANCER RESEARCH

GCN5 inhibition prevents IL-6-induced prostate cancer metastases through PI3K/PTEN/Akt signaling by inactivating Egr-1

(2018) Guangfeng Shao et al.   BIOSCIENCE REPORTS

6-Phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 and 4: A pair of valves for fine-tuning of glucose metabolism in human cancer

(2018) Mei Yi et al.   Molecular Metabolism

Current Knowledge in Thyroid Cancer—From Bench to Bedside

(2017) Daniela Grimm   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Expression of Hypoxia-Associated Protein HIF-1α in Follicular Thyroid Cancer is Associated with Distant Metastasis

(2017) Aumayr Klaus et al.   PATHOLOGY & ONCOLOGY RESEARCH

Glycolysis-related protein expression in thyroid cancer

(2017) Ji Hae Nahm et al.   TUMOR BIOLOGY

Metabolic Alterations of Thyroid Cancer as Potential Therapeutic Targets

(2017) Domenico Ciavardelli et al.   Biomed Research International

HIF-1α activates hypoxia-induced PFKFB4 expression in human bladder cancer cells

(2016) Hao Zhang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Cancer statistics in China, 2015

(2016) Wanqing Chen et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Thyroid cancer

(2016) Maria E Cabanillas et al.   LANCET

Phosphorylation of PPARγ at Ser84 promotes glycolysis and cell proliferation in hepatocellular carcinoma by targeting PFKFB4

(2016) Yuxin Shu et al.   Oncotarget

The oncoprotein HBXIP promotes migration of breast cancer cells via GCN5-mediated microtubule acetylation

(2015) Leilei Li et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The Histone Acetyltransferase GCN5 Expression Is Elevated and Regulated by c-Myc and E2F1 Transcription Factors in Human Colon Cancer

(2015) Yan-Wei Yin et al.   GENE EXPRESSION

GC-MS-based metabolomic analysis of human papillary thyroid carcinoma tissue

(2015) MINJIAN CHEN et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

GCN5 Potentiates Glioma Proliferation and Invasion via STAT3 and AKT Signaling Pathways

(2015) Kun Liu et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

New and emerging HDAC inhibitors for cancer treatment

(2014) Alison C. West et al.   JOURNAL OF CLINICAL INVESTIGATION

PI3K/PTEN/Akt and TSC/mTOR signaling pathways, ovarian dysfunction, and infertility: an update

(2014) Annu Makker et al.   JOURNAL OF MOLECULAR ENDOCRINOLOGY

Histone deacetylation of NIS promoter underlies BRAF V600E-promoted NIS silencing in thyroid cancer

(2013) Zongjing Zhang et al.   ENDOCRINE-RELATED CANCER

Overexpression of AKT decreases the chemosensitivity of gastric cancer cells to cisplatin in vitro and in vivo

(2013) LING-LI ZHANG et al.   Molecular Medicine Reports

Glucose Transporter 1 Expression, Tumor Proliferation, and Iodine/Glucose Uptake in Thyroid Cancer With Emphasis on Poorly Differentiated Thyroid Carcinoma

(2012) Florian Grabellus et al.   CLINICAL NUCLEAR MEDICINE

GCN5 regulates the activation of PI3K/Akt survival pathway in B cells exposed to oxidative stress via controlling gene expressions of Syk and Btk

(2011) Hidehiko Kikuchi et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Akt signalling in health and disease

(2011) Ingeborg Hers et al.   CELLULAR SIGNALLING

Expression of hypoxia-inducible factor 1α in thyroid carcinomas

(2009) N Burrows et al.   ENDOCRINE-RELATED CANCER

Regulation of glucose metabolism by 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatases in cancer

(2009) Abdullah Yalcin et al.   EXPERIMENTAL AND MOLECULAR PATHOLOGY

Mitochondrial Autophagy Is an HIF-1-dependent Adaptive Metabolic Response to Hypoxia

(2008) Huafeng Zhang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY