Oscillatory expression of Hes1 regulates cell proliferation and neuronal differentiation in the embryonic brain

Coupling delay controls synchronized oscillation in the segmentation clock

(2020) Kumiko Yoshioka-Kobayashi et al.   NATURE

High Hes1 expression and resultant Ascl1 suppression regulate quiescent vs. active neural stem cells in the adult mouse brain

(2019) Risa Sueda et al.   GENES & DEVELOPMENT

Oscillations of MyoD and Hes1 proteins regulate the maintenance of activated muscle stem cells

(2019) Ines Lahmann et al.   GENES & DEVELOPMENT

Signaling Dynamics Control Cell Fate in the Early Drosophila Embryo

(2019) Heath E. Johnson et al.   DEVELOPMENTAL CELL

Quantitative single-cell live imaging links HES5 dynamics with cell-state and fate in murine neurogenesis

(2019) Cerys S. Manning et al.   Nature Communications

Evolution of Cortical Neurogenesis in Amniotes Controlled by Robo Signaling Levels

(2018) Adrián Cárdenas et al.   CELL

The E3 ubiquitin ligase SCFFBXL14complex stimulates neuronal differentiation by targeting the Notch signaling factor HES1 for proteolysis

(2017) Fangfang Chen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Oscillatory control of Delta-like1 in cell interactions regulates dynamic gene expression and tissue morphogenesis

(2016) Hiromi Shimojo et al.   GENES & DEVELOPMENT

Persistence, period and precision of autonomous cellular oscillators from the zebrafish segmentation clock

(2016) Alexis B Webb et al.   eLife

Nonsense-Mediated mRNA Decay: Degradation of Defective Transcripts Is Only Part of the Story

(2015) Feng He et al.   Annual Review of Genetics

Ultradian oscillations and pulses: coordinating cellular responses and cell fate decisions

(2014) A. Isomura et al.   DEVELOPMENT

bHLH Factors in Self-Renewal, Multipotency, and Fate Choice of Neural Progenitor Cells

(2014) Itaru Imayoshi et al.   NEURON

Encoding and Decoding Cellular Information through Signaling Dynamics

(2013) Jeremy E. Purvis et al.   CELL

Stochastic ERK Activation Induced by Noise and Cell-to-Cell Propagation Regulates Cell Density-Dependent Proliferation

(2013) Kazuhiro Aoki et al.   MOLECULAR CELL

Functional Roles of Pulsing in Genetic Circuits

(2013) J. H. Levine et al.   SCIENCE

Oscillatory Control of Factors Determining Multipotency and Fate in Mouse Neural Progenitors

(2013) I. Imayoshi et al.   SCIENCE

Patterning embryos with oscillations: structure, function and dynamics of the vertebrate segmentation clock

(2012) A. C. Oates et al.   DEVELOPMENT

Frequency-Modulated Pulses of ERK Activity Transmit Quantitative Proliferation Signals

(2012) John G. Albeck et al.   MOLECULAR CELL

MicroRNA-9 Modulates Hes1 Ultradian Oscillations by Forming a Double-Negative Feedback Loop

(2012) Boyan Bonev et al.   Cell Reports

Accelerating the Tempo of the Segmentation Clock by Reducing the Number of Introns in the Hes7 Gene

(2012) Yukiko Harima et al.   Cell Reports

Vertebrate Segmentation: From Cyclic Gene Networks to Scoliosis

(2011) Olivier Pourquié   CELL

A novel function of the proneural factor Ascl1 in progenitor proliferation identified by genome-wide characterization of its targets

(2011) D. S. Castro et al.   GENES & DEVELOPMENT

Intronic delay is essential for oscillatory expression in the segmentation clock

(2011) Y. Takashima et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The cyclic gene Hes1 contributes to diverse differentiation responses of embryonic stem cells

(2009) T. Kobayashi et al.   GENES & DEVELOPMENT

Pulsatile Stimulation Determines Timing and Specificity of NF- B-Dependent Transcription

(2009) L. Ashall et al.   SCIENCE

Selection of differentiating cells by different levels of delta-like 1 among neural precursor cells in the developing mouse telencephalon

(2008) D. Kawaguchi et al.   DEVELOPMENT

Intron Delays and Transcriptional Timing during Development

(2008) Ian A. Swinburne et al.   DEVELOPMENTAL CELL

Intron length increases oscillatory periods of gene expression in animal cells

(2008) I. A. Swinburne et al.   GENES & DEVELOPMENT

Oscillations in Notch Signaling Regulate Maintenance of Neural Progenitors

(2008) Hiromi Shimojo et al.   NEURON

Control of the Reversibility of Cellular Quiescence by the Transcriptional Repressor HES1

(2008) L. Sang et al.   SCIENCE