Article
Orthopedics
Feng-Chen Kao, Yao-Chun Hsu, Tzu-Shan Chen, Pao-Hsin Liu, Yuan-Kun Tu
Summary: Sacroplasty is an effective method for treating osteoporotic SIFs, with a combination of long- and short-axis alar sacroplasty techniques showing comparable pain relief outcomes but longer operation times compared to short-axis sacroplasty under fluoroscopic guidance. no major complications were noted in either group.
JOURNAL OF ORTHOPAEDIC SURGERY AND RESEARCH
(2021)
Article
Clinical Neurology
Buse Sarigul, Ahmet Ogrenci, Mesut Yilmaz, Orkun Koban, Mazhar Mammadov, Sedat Dalbayrak
Summary: Sacral insufficiency fracture (SIF) should be considered in elderly and osteoporotic patients with back and pelvic pain. MRI with coronal STIR imaging is recommended for diagnosing SIF. Sacroplasty provides better and faster pain relief compared to conservative management.
EUROPEAN SPINE JOURNAL
(2023)
Article
Geriatrics & Gerontology
Raphael Lotan, Oded Hershkovich, Yigal Bronstein, Joel Finkelstein
Summary: The study examines the feasibility, safety, and outcomes of a novel sacral percutaneous injection technique for treating sacral insufficiency fractures. The results indicate that the technique is effective in providing pain relief and improving ambulation for patients with higher complexity SIF.
GERIATRIC ORTHOPAEDIC SURGERY & REHABILITATION
(2022)
Article
Orthopedics
Julian Ramin Andresen, Sebastian Radmer, Reimer Andresen, Axel Prokop, Guido Schroeder, Urs Nissen, Hans-Christof Schober
Summary: This study compared the clinical outcomes of conservative, interventional, and surgical treatment for sacral fragility fractures (FFS). The results showed that patients with lower levels of pain benefited from conservative therapy, while those with higher levels of pain benefited from sacroplasty. Surgical treatment provided better pain relief and mobility, but more complex fracture types required longer recovery time. Additionally, both sacroplasty and osteosynthesis improved independence and reduced mortality for patients.
BMC MUSCULOSKELETAL DISORDERS
(2022)
Article
Medicine, General & Internal
Taro Yamauchi, Sagar Sharma, Sarath Chandra, Masato Tanaka, Yoshihiro Fujiwara, Shinya Arataki, Ayush Sharma, Yusuke Yokoyama, Toshinori Oomori, Akihiro Kanamaru, Shin Masuda, Noriyuki Shimizu, Kenta Torigoe, Osamu Honda
Summary: This study evaluates the role of lumbar magnetic resonance imaging (MRI) and computed tomography (CT) in the diagnosis of sacral insufficiency fractures (SIF). The results show that lumbar MRI has higher sensitivity and can detect more complex fracture patterns compared to CT. MRI can be useful for early detection of SIF, recognition of concomitant pathologies, and adequate treatment for patients.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Oncology
Mengxiong Sun, Dongqing Zuo, Hongsheng Wang, Jiakang Sheng, Xiaojun Ma, Chongren Wang, Pengfei Zan, Yingqi Hua, Wei Sun, Zhengdong Cai
Summary: This study retrospectively analyzed the data of 73 patients with sacral metastases treated in our hospital, and found that surgical treatment can significantly improve symptoms and quality of life for patients.
FRONTIERS IN ONCOLOGY
(2021)
Editorial Material
Radiology, Nuclear Medicine & Medical Imaging
Nuh Filizoglu, Onur Bugdayci, Salih Ozguven
Summary: This case study highlights the importance of recognizing potential false-positive results in Ga-68-DOTATATE PET/CT imaging, as seen in a 47-year-old male patient diagnosed with a neuroendocrine tumor of the pancreas but was later found to have a sacral insufficiency fracture.
CLINICAL NUCLEAR MEDICINE
(2021)
Article
Clinical Neurology
Q. -h. Tian, K. Han, T. Wang, D. -l. Min, C. -g. Wu
Summary: This study compared the efficacy and safety of percutaneous sacroplasty alone versus percutaneous sacroplasty plus radiofrequency ablation for the treatment of painful sacral metastases. The combination of percutaneous sacroplasty and radiofrequency ablation appeared to be more effective than percutaneous sacroplasty alone.
AMERICAN JOURNAL OF NEURORADIOLOGY
(2022)
Review
Medicine, General & Internal
Praise Briggs, Samuel W. King, Tim Staniland, Shivkumar Gopal, Rajesh Shah, Mukai Chimutengwende-Gordon
Summary: Sacral insufficiency fractures can be treated conservatively, with surgical fixation or sacroplasty. This systematic review compared the outcomes of different treatment modalities and found that sacroplasty resulted in superior pain relief and shorter hospital stay compared to conservative management or surgical fixation. The review included elderly patients with sacral insufficiency fractures and excluded fractures due to high-energy trauma or malignancy or in non-elderly patients. The findings support the use of sacroplasty as the preferred treatment option for these fractures.
CUREUS JOURNAL OF MEDICAL SCIENCE
(2023)
Article
Clinical Neurology
Isabel Graul, Sophia Vogt, Patrick Strube, Alexander Hoelzl
Summary: This retrospective observational study evaluated the role of lumbar MRI in diagnosing sacral insufficiency fractures, showing MRI to be more sensitive in fracture detection compared to X-ray and CT. MRI also revealed a more complex fracture pattern and additional pathologies in the lumbar spine and pelvis. Performing MRI of the lumbar spine with coronal STIR sequence is recommended for elderly patients with suddenly increasing low back pain.
GLOBAL SPINE JOURNAL
(2021)
Review
Medicine, General & Internal
Zhanglu Fang, Jianhua Cao, Xun Wang, Li Zhang
Summary: This case report highlights the importance of clinical symptoms and imaging examinations in diagnosing bilateral femoral neck stress fractures in elderly patients.
Article
Emergency Medicine
Thomas Mendel, Bernhard Wilhelm Ullrich, Gunther Olaf Hofmann, Philipp Schenk, Felix Goehre, Stefan Schwan, Friederike Klauke
Summary: This study aimed to investigate the pathogenetic mechanism, progression, and instability in geriatric bilateral fragility fractures of the sacrum (BFFSs) by analyzing imaging data from 78 cases. The results showed a stagewise BFFS progression starting with unilateral sacral disruption, followed by contralateral lesion, and subsequent bone disruption causing iliolumbar ligament avulsion. MRI is recommended for detecting bone edema in BFFS cases.
EUROPEAN JOURNAL OF TRAUMA AND EMERGENCY SURGERY
(2021)
Article
Endocrinology & Metabolism
Ifaz T. Haider, Lindsay L. Loundagin, Andrew Sawatsky, Paul J. Kostenuik, Steven K. Boyd, W. Brent Edwards
Summary: This study quantified the relationship between antiresorptive treatment and fatigue life in bone from ovariectomized cynomolgus monkeys. The results showed that the antiresorptive treatment groups had higher fatigue-life measurements and improved bone microstructure and composition compared to the control group. Therefore, antiresorptive treatment may have a protective effect against fatigue fractures.
JOURNAL OF BONE AND MINERAL RESEARCH
(2023)
Editorial Material
Radiology, Nuclear Medicine & Medical Imaging
Yuhu Lv, Xiaoli Lan, Chunxia Qin
Summary: In cancer patients, the possibility of insufficiency fracture should be considered when accidentally symmetrically increased sacral Ga-68-FAPI uptake appears. Careful differential diagnosis should be made in such cases.
CLINICAL NUCLEAR MEDICINE
(2021)
Article
Orthopedics
Julian Ramin Andresen, Sebastian Radmer, Axel Prokop, Mathias Wollny, Urs Nissen, Hans-Christof Schober, Reimer Andresen
Summary: The article discusses the treatment methods for sacral insufficiency fractures and the procedures of cement augmentation, including different techniques, indications, complications, and clinical outcomes. New classifications and individual clinical situations need to be considered, highlighting the importance of conservative therapy and possible complications during surgical procedures.
Review
Clinical Neurology
Laxmaiah Manchikanti, Nebojsa Nick Knezevic, Emilija Knezevic, Salahadin Abdi, Mahendra R. Sanapati, Amol Soin, Bradley W. Wargo, Annu Navani, Sairam Atluri, Christopher G. Gharibo, Thomas T. Simopoulos, Radomir Kosanovic, Alaa Abd-Elsayed, Alan D. Kaye, Joshua A. Hirsch
Summary: This systematic review and meta-analysis examines the effectiveness of radiofrequency neurotomy as a therapeutic intervention for chronic neck pain and cervicogenic headaches. The analysis reveals that radiofrequency neurotomy shows level II evidence in managing chronic neck pain, with moderate to high clinical applicability. However, the evidence is level III to IV in managing cervicogenic headaches, suggesting a relatively lower efficacy.
Review
Anesthesiology
Laxmaiah Manchikanti, Emilija Knezevic, Richard E. Latchaw, Nebojsa Nick Knezevic, Salahadin Abdi, Mahendra R. Sanapati, Peter S. Staats, Christopher G. Gharibo, Thomas T. Simopoulos, Shalini Shah, Alaa Abd-Elsayed, Annu Navani, Alan D. Kaye, Sheri L. Albers, Joshua A. Hirsch
Summary: A reanalysis of the Cochrane Review data suggests that epidural injections are effective in managing chronic low back and lower extremity pain. However, there are conflicting views on the effectiveness of epidural injections in different systematic reviews and meta-analyses.
Letter
Anesthesiology
Laxmaiah Manchikanti, Sairam Atluri, Joshua A. Hirsch
Letter
Anesthesiology
Laxmaiah Manchikanti, Joshua A. Hirsch
Article
Anesthesiology
Laxmaiah Manchikanti, Vidyasagar Pampati, Mahendra R. Sanapati, Radomir Kosanovic, Douglas P. Beall, Sairam Atluri, Salahadin Abdi, Shalini Shah, Mark Boswell, Alan D. Kaye, Amol Soin, Christopher G. Gharibo, Bradley W. Wargo, Joshua A. Hirsch
Summary: The COVID-19 pandemic has significantly impacted the utilization of interventional techniques in managing chronic pain in the Medicare population. From 2019 to 2020, there was an 18.7% decrease in utilization of all interventional techniques, with even greater decreases observed for specific procedures. The overall decline in utilization from 2010 to 2020 was 22.0% per 100,000 Medicare population.
Review
Anesthesiology
Laxmaiah Manchikanti, Thomas T. Simopoulos, Vidyasagar Pampati, Maanasa Manchikanti, Radomir Kosanovic, Salahadin Abdi, Mahendra R. Sanapati, Dhanalakshmi Koyyalagunta, Nebojsa Nick Knezevic, Douglas P. Beall, Amol Soin, Alan D. Kaye, Alaa Abd-Elsayed, Joshua A. Hirsch
Summary: The COVID-19 pandemic has had a significant impact on the utilization patterns of sacroiliac joint interventions, with a decrease in intraarticular injections and fusion, but an increase in arthrodesis.
Article
Anesthesiology
Amol Soin, Megan Hirschbeck, Michael Verdon, Laxmaiah Manchikanti
Summary: Chronic spinal pain is a prevalent condition with escalating healthcare costs and increasing disability rates. Utilizing artificial intelligence and machine learning techniques for diagnosis can improve accuracy and assist in clinical decision-making.
Review
Anesthesiology
Laxmaiah Manchikanti, Vanila Mathur Singh, Peter S. Staats, Andrea M. Trescot, John Prunskis, Nebojsa Nick Knezevic, Amol Soin, Alan D. Kaye, Sairam Atluri, Mark Boswell, Alaa Abd-Elsayed, Joshua A. Hirsch
Summary: Amidst the COVID-19 pandemic, overdose death rates involving various types of opioids have been increasing, including prescription opioids. However, the problem of misuse, abuse, and diversion of prescription opioids has been less significant in recent years compared to illicit opioids. There has been an oversimplification of the issue by limiting prescription opioids without considering their legitimate uses for chronic pain. Similarly, interventional pain management procedures have also been affected by policies aimed at reducing overuse and abuse, resulting in declining utilization rates. These changes can be attributed to various factors, such as the misapplication of prescribing guidelines, increased access to illicit opioids, and the impact of the COVID-19 pandemic. These trends indicate a fourth wave of the opioid epidemic, which warrants attention and reevaluation of current policies.
Article
Anesthesiology
Laxmaiah Manchikanti, Vidyasagar Pampati, Sachin Sunny Jha, Mahendra R. Sanapati, Amol Soin, Shalini Shah, Alan D. Kaye, Joshua A. Hirsch
Summary: The COVID-19 pandemic has had a significant detrimental impact on interventional pain management practices, resulting in decreased income for providers, a reduction in new patient volume, and a significant decline in various interventional procedures.
Article
Anesthesiology
Laxmaiah Manchikanti, Radomir Kosanovic, Vidyasagar Pampati, Mahendra R. Sanapati, Amol Soin, Nebojsa Nick Knezevic, Bradley W. Wargo, Joshua A. Hirsch
Summary: This study compares the clinical outcomes and cost utility of therapeutic lumbar facet joint nerve blocks with radiofrequency neurotomy in managing chronic low back pain of facet joint origin. The results show similar outcomes in terms of pain relief and cost utility for both procedures.
Article
Anesthesiology
Jagadesh N. Nagireddi, Amanya Ketan Vyas, Mahendra R. Sanapati, Amol Soin, Laxmaiah Manchikanti
Summary: This article analyzes the application of artificial intelligence and machine learning in pain analysis and management, and suggests that facial expression and spinal diagnosis and management are ready for implementation. The article summarizes the available literature and proposes further research directions.
Article
Anesthesiology
Sairam Atluri, Matthew B. Murphy, Ryan Dragella, Jessica Herrera, Kwadwo Boachie-Adjei, Sachi Bhati, Vivek Manocha, Navneet Boddu, Pavan Yerramsetty, Zaid Syed, Meghana Ganjam, Divit Jain, Zaynab Syed, Nikhil Grandhi, Laxmaiah Manchikanti
Summary: This study, for the first time, demonstrated promising results in the application of BM-MSCs to multiple structures in severe degenerative spinal disease, achieving significant improvements in functional status and pain relief.
Article
Anesthesiology
Laxmaiah Manchikanti, Vidyasagar Pampati, Mahendra R. Sanapati, Joshua A. Hirsch
Summary: This study compared the clinical outcomes and cost utility of therapeutic medial branch blocks with radiofrequency neurotomy in managing chronic neck pain of facet joint origin. The results showed that both treatments had significantly improved pain relief at 12 months, with similar costs. However, the duration of pain relief was slightly shorter with medial branch blocks.
Article
Anesthesiology
Laxmaiah Manchikanti, Vidyasagar Pampati, Bramha Prasad Vangala, Amol Soin, Mahendra R. Sanapati, Srinivasa Thota, Joshua A. Hirsch
Summary: The analysis conducted on the utilization and expenditures of spinal cord stimulation in the FFS Medicare population from 2009 to 2018 revealed significant increases in trials, implants, and overall costs.
Review
Anesthesiology
Laxmaiah Manchikanti, Emilija Knezevic, Nebojsa Nick Knezevic, Mahendra R. Sanapati, Srinivasa Thota, Alaa Abd-Elsayed, Joshua A. Hirsch
Summary: Epidural injections with or without steroids for radiculopathy showed significant effectiveness with Level I or strong evidence for local anesthetic with steroids and Level II to I or moderate to strong evidence with local anesthetic alone.
