Review
Obstetrics & Gynecology
Jeffrey Pea, Jahnay Bryan, Cynthia Wan, Alexis L. Oldfield, Kiran Ganga, Faith E. Carter, Lynn M. Johnson, Marla E. Lujan
Summary: This systematic review and diagnostic meta-analysis examined the diagnostic accuracy of ultrasonographic features of ovarian morphology in the diagnosis of PCOS. The results showed that follicle number per ovary (FNPO) was the most accurate diagnostic marker in adult women. Ovarian volume (OV) and follicle number per single cross-section (FNPS) had similar sensitivities to FNPO but lower specificities and accuracies. In adolescents, ovarian volume may be a reliable ultrasonographic marker for PCOS diagnosis, although current evidence is limited.
HUMAN REPRODUCTION UPDATE
(2023)
Article
Psychology, Multidisciplinary
Yunmei Guo, Ying Liu, Xin Yan, Rui Ding, LianHong Wang
Summary: This study confirms that a transtheoretical model based on multidimensional life management has positive effects on healthy behavior, self-efficacy, the number of unplanned outpatient admissions, and anthropometrics in patients with PCOS.
FRONTIERS IN PSYCHOLOGY
(2022)
Review
Biology
Chan-Hee Kim, Seon-Heui Lee
Summary: This study observed significant improvements in reproductive function and metabolic index in the group that underwent lifestyle modifications compared to the control group. The combination therapy of diet and exercise showed better results in improving insulin levels and menstrual cycles.
Article
Medicine, General & Internal
Augustina Gyliene, Vestina Straksyte, Inga Zaboriene
Summary: Polycystic ovary syndrome (PCOS) is a common endocrinopathy among women of reproductive age associated with hyperandrogenism, oligo-amenorrhea, and infertility. Ultrasonographic assessment is a non-invasive, cheap, and effective tool for diagnosing PCOS.
Article
Endocrinology & Metabolism
Izabela Chudzicka-Strugala, Anna Kubiak, Beata Banaszewska, Barbara Zwozdziak, Martyna Siakowska, Leszek Pawelczyk, Antoni J. Duleba
Summary: The study demonstrated that in women with PCOS, lifestyle modifications combined with synbiotic supplementation can significantly decrease body weight, waist circumference, hip circumference, and thigh circumference, as well as lead to a significant reduction in serum testosterone levels.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
(2021)
Article
Obstetrics & Gynecology
Heidi Vanden Brink, Adrienne J. Pisch, Marla E. Lujan
Summary: This study found variability in follicle number per ovary assessments across different ultrasonographic methods, with 2D-RT potentially misclassifying PCOM, while 2D-RT with Grid and MPV-RT could be clinically feasible alternatives for obtaining FNPO and classifying PCOM. Efforts to reduce variation in FNPO will clarify the relevance of PCOM in women's health.
FERTILITY AND STERILITY
(2021)
Article
Health Care Sciences & Services
Jamie L. Benham, Jane E. Booth, Christine M. Friedenreich, Doreen M. Rabi, Ronald J. Sigal
Summary: The most effective and cost-efficient ways to recruit women with polycystic ovary syndrome were through unpaid advertisements and Facebook advertisements, with no participants reporting learning about the trial through multiple methods. Traditional media was also more successful in attracting participants compared to Facebook and unpaid advertisements.
JOURNAL OF MEDICAL INTERNET RESEARCH
(2021)
Article
Endocrinology & Metabolism
W. Colin Duncan, Linda M. Nicol, Rosie O'Hare, Jason Witherington, Jason A. Miranda, Bruce K. Campbell, Jennifer L. Thomas, Michael T. Rae
Summary: Although the ovary is richly innervated, there is no evidence to suggest that sympathetic nerves play a role in ovarian function or the growth and survival of small follicles.
FRONTIERS IN ENDOCRINOLOGY
(2023)
Review
Nutrition & Dietetics
Valeria Calcaterra, Hellas Cena, Francesca Sottotetti, Chiara Hruby, Nagaia Madini, Noemi Zelaschi, Gianvincenzo Zuccotti
Summary: Polycystic ovary syndrome (PCOS) is the most common endocrine disorder in women of reproductive age and is mainly driven by hyperandrogenism, hyperinsulinism, and insulin resistance. Lifestyle and dietary interventions, particularly the quality and quantity of carbohydrates consumed, play a crucial role in the management of PCOS, and the ketogenic diet (KD) has shown promise in improving insulin resistance and carbohydrate metabolism. Further studies are needed to determine the specific effects of the very low-calorie ketogenic diet (LCKD) in adolescents with PCOS and excessive body weight. Rating: 8/10
Article
Nutrition & Dietetics
Shanshan Mei, Jie Ding, Kaili Wang, Zhexin Ni, Jin Yu
Summary: The results of this study suggest that the MED/LC diet model is an effective treatment for overweight PCOS patients. It significantly restores their menstrual cycle, improves their anthropometric parameters, corrects their disturbed endocrine levels, and has better overall effectiveness compared to the LF diet model. Therefore, the MED/LC diet model is recommended for clinical treatment of overweight PCOS patients.
FRONTIERS IN NUTRITION
(2022)
Article
Biochemistry & Molecular Biology
Qi Jiang, Ruolan Miao, Yuhuan Wang, Wenqi Wang, Dingying Zhao, Yue Niu, Qiaoqiao Ding, Yan Li, Peter C. K. Leung, Daimin Wei, Zi-Jiang Chen
Summary: Polycystic ovary syndrome (PCOS) is a common and heterogeneous endocrine disorder, which is the main cause of ovulatory obstacle associated with abnormal folliculogenesis. Dysfunction of ovarian granulosa cells (GCs) is recognized as a major factor that underlies abnormal follicle maturation. The expression of angiopoietin-like 4 (ANGPTL4) in GCs differs between patients with and without PCOS. In this study, ANGPTL4 was found to be upregulated in patients with PCOS and its overexpression inhibited the proliferation of GCs through the EGFR/JAK1/STAT3-mediated induction of p21, providing a novel epigenetic mechanism for the pathogenesis of PCOS.
Article
Medicine, General & Internal
Malgorzata Mizgier, Grazyna Jarzabek-Bielecka, Dorota Formanowicz, Elzbieta Jodlowska-Siewert, Kinga Mruczyk, Angelika Cisek-Wozniak, Witold Kedzia, Justyna Opydo-Szymaczek
Summary: The study found that girls with PCOS had higher fat intake and lower levels of physical activity compared to the control group. Additionally, PCOS patients showed abnormal levels of metabolic and inflammatory markers.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Nutrition & Dietetics
Stephanie Cowan, Angela Grassi, Lynn Monahan Couch, Yvonne Jeanes, Siew Lim, Stephanie Pirotta, Jeff Harris, Caroline McGirr, Lisa Moran
Summary: Polycystic ovary syndrome (PCOS) is a complex endocrine disorder that affects 13% of reproductive-aged women. A study found that a quarter or less of women sought lifestyle advice from health professionals, while the majority relied on online sources for information. Many women implemented dietary and physical activity interventions inconsistent with evidence-based practices for managing PCOS. This highlights the need to increase engagement with qualified health professionals and address the dissemination of inaccurate and ineffective lifestyle advice online.
Review
Endocrinology & Metabolism
Lino Del Pup, Angelo Cagnacci
Summary: Lifestyle change is the primary treatment for managing women with PCOS, and using the IMPROVE method can help improve adherence to lifestyle advice. Emphasizing information delivery and motivation, while listening to patients' feedback for better encouragement, empowering patients to maintain long-term self-adherence is the ultimate goal.
GYNECOLOGICAL ENDOCRINOLOGY
(2021)
Review
Cell Biology
Xue-Ling Xu, Shou-Long Deng, Zheng-Xing Lian, Kun Yu
Summary: Female infertility is mainly caused by ovulation disorders, with polycystic ovary syndrome (PCOS) being the most prevalent. PCOS is associated with abnormal function of estrogen and estrogen receptors (ERs), affecting cellular activities. Selective estrogen receptor modulators (SERMs) like tamoxifen and clomiphene have shown clinical applications for subfertility with PCOS, but further understanding of the role of ER in PCOS is needed.
Review
Biochemistry & Molecular Biology
Maedeh Babapour, Hamed Mohammadi, Maryam Kazemi, Amir Hadi, Mahsa Rezazadegan, Gholamreza Askari
Summary: Women with PCOS have lower serum magnesium concentrations compared to the control group, especially in overweight or obese women. Further research and management of magnesium status may be crucial for this clinical population.
BIOLOGICAL TRACE ELEMENT RESEARCH
(2021)
Review
Food Science & Technology
Amir Hadi, Makan Pourmasoumi, Maryam Kazemi, Ameneh Najafgholizadeh, Wolfgang Marx
Summary: Synbiotic interventions significantly reduce systolic blood pressure in adults, especially in longer trials, as supplements, and with younger participants. Significant improvements in both systolic and diastolic blood pressure levels were seen in subgroups with lower body mass index (<30 kg/m(2)).
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION
(2022)
Review
Obstetrics & Gynecology
Maryam Kazemi, Joy Y. Kim, Cynthia Wan, Julia D. Xiong, Stephen A. Parry, Ricardo Azziz, Marla E. Lujan
Summary: This study compared the cardiometabolic and reproductive health risk between Hispanic and White women with polycystic ovary syndrome in the United States. It found that Hispanic women had greater impairments in glucoregulatory status but no significant differences in reproductive risks could be concluded.
AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY
(2022)
Review
Nutrition & Dietetics
Amir Hadi, Arman Arab, Saman Khalesi, Nahid Rafie, Marzieh Kafeshani, Maryam Kazemi
Summary: The supplementation with pro-/synbiotics may be beneficial in reducing total cholesterol levels in adults with MetS. However, there is no evidence supporting the effectiveness of pro-/synbiotics consumption on other anthropometric or metabolic outcomes of MetS. Further investigations with larger sample sizes are needed to confirm these findings.
CLINICAL NUTRITION
(2021)
Review
Medicine, General & Internal
Alexis L. Oldfield, Maryam Kazemi, Marla E. Lujan
Summary: Some studies suggest that obesity may reduce AMH levels, while others show comparable levels between groups. There are limitations in existing research, so the degree to which obesity may impact AMH levels remains uncertain at this time.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Nutrition & Dietetics
Arman Arab, Fariborz Khorvash, Maryam Kazemi, Zahra Heidari, Gholamreza Askari
Summary: The study showed that the Dietary Approaches to Stop Hypertension (DASH) diet can improve health outcomes in women with migraines by reducing migraine frequency and severity, as well as decreasing depression and stress levels. Further research is needed to confirm the findings.
BRITISH JOURNAL OF NUTRITION
(2022)
Review
Food Science & Technology
Amir Hadi, Omid Asbaghi, Maryam Kazemi, Hossein Khadem Haghighian, Ana Pantovic, Ehsan Ghaedi, Firoozeh Abolhasani Zadeh
Summary: Consuming pistachio nuts can lower TC, LDL-C, and TG levels, but does not affect HDL-C levels. Consuming pistachio nuts may improve lipid profiles and protect against cardiometabolic diseases.
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION
(2023)
Review
Obstetrics & Gynecology
Maryam Kazemi, Joy Y. Kim, Cynthia Wan, Julia D. Xiong, Julia Michalak, Isabella B. Xavier, Kiran Ganga, Chau Thien Tay, Jessica A. Grieger, Stephen A. Parry, Lisa J. Moran, Marla E. Lujan
Summary: This study aimed to explore and compare the dietary and physical activity behaviors between women with polycystic ovary syndrome (PCOS) and those without PCOS. The findings indicated that women with PCOS had lower overall diet quality, poorer dietary intake (higher cholesterol and lower magnesium and zinc), and lower levels of physical activity compared to women without PCOS. These results highlight the need for targeted interventions to address these lifestyle behaviors in order to manage the complications associated with PCOS.
HUMAN REPRODUCTION UPDATE
(2022)
Review
Nutrition & Dietetics
Amir Hadi, Omid Asbaghi, Maryam Kazemi, Hossein Khadem Haghighian, Ehsan Ghaedi
Summary: This systematic review and meta-analysis evaluated the effects of pistachio consumption on glucoregulatory status in individuals with a high risk of cardiovascular disease (CVD). The results showed that pistachio consumption, isocaloric with other foods, can decrease fasting blood sugar and insulin concentrations in individuals with a high risk of CVD. However, there was no significant change in insulin resistance levels. It is recommended to conduct well-designed trials with an adequate sample size focusing on diabetic populations due to the limited availability of studies with diabetic cases and relatively small sample sizes.
BRITISH JOURNAL OF NUTRITION
(2023)
Review
Public, Environmental & Occupational Health
Seyadeh Narges Mazloomi, Sepide Talebi, Maryam Kazemi, Seyed Mojtaba Ghoreishy, Seyedeh Parisa Moosavian, Parsa Amirian, Hamed Mohammadi, Saeedeh Nouri-Majd, Wolfgang Marx, Mohammad Ali Hojjati Kermani, Sajjad Moradi
Summary: This study examined the association between food insecurity and sleep quality and quantity in adults. The results showed that food insecurity was associated with an increased risk of poor sleep quality and inconsistent sleep duration. Addressing food insecurity can have a positive impact on sleep in adults.
PUBLIC HEALTH NUTRITION
(2023)
Article
Obstetrics & Gynecology
Hannah E. Pierson, Jesse Invik, Jim Meriano, Roger A. Pierson
Summary: This study aimed to investigate whether Gardner embryo grades can be converted to numeric interval variables to improve the incorporation of embryo grading in statistical analyses. An equation, the numerical embryo quality scoring index (NEQsi), was developed to convert Gardner embryo grades to regular interval scale variables. The NEQsi system was validated with a retrospective chart analysis of 1711 IVF cycles. The results showed that NEQsi produces interval numerical scores that range from 2 to 11, and there is a positive linear relationship between NEQsi scores and the probability of pregnancy.
REPRODUCTIVE BIOMEDICINE ONLINE
(2023)
Article
Nutrition & Dietetics
Philip D. Chilibeck
Summary: Ice hockey players are at high risk for COVID-19 due to close contact and poor arena ventilation. To prevent transmission, strategies such as reducing crowding, minimizing player clustering, conducting at-home rapid tests, screening for symptoms, and implementing face mask or vaccine recommendations for spectators, coaches, and players should be implemented. Although face masks have minimal impact on performance, they can effectively reduce COVID-19 transmission. Furthermore, adjustments should be made to shift lengths to reduce perceived exertion, and players should be encouraged to adopt a classic hockey stance for better peripheral vision. These strategies are crucial in preventing the cancellation of practices or games, which offer important physical and psychological benefits.
APPLIED PHYSIOLOGY NUTRITION AND METABOLISM
(2023)
Article
Obstetrics & Gynecology
Donna R. Chizen, Dominique C. Rislund, Lynne M. Robertson, Hyun J. Lim, Togas Tulandi, Antonio R. Gargiulo, Rudy Leon De Wilde, Aleksey Velygodskiy, Roger A. Pierson
Summary: The study aimed to test the hypothesis that intraperitoneal instillation of L-alanyl-L-glutamine (AG) could reduce the incidence, extent, and severity of adhesions following myomectomy, and to establish the safety and tolerability of AG in humans. The results showed that AG can reduce the incidence, extent, and severity of post-operative adhesions. No serious adverse events were reported in the AG group. These findings confirm the effects of AG on the cellular mechanisms of adhesiogenesis and lay the foundation for further research and treatment in adhesion prophylaxis.
EUROPEAN JOURNAL OF OBSTETRICS & GYNECOLOGY AND REPRODUCTIVE BIOLOGY
(2023)
Article
Physiology
Mojtaba Kaviani, Keely A. Shaw, Darren G. Candow, Jonathan P. Farthing, Philip D. Chilibeck
Summary: The study aimed to investigate the effects of hemp supplementation on trained young adults during resistance training. The results showed that hemp supplementation had sex-specific beneficial effects on muscle accretion and torque.
EUROPEAN JOURNAL OF APPLIED PHYSIOLOGY
(2023)
Article
Neurosciences
Arghavan Balali, Elham Karimi, Maryam Kazemi, Amir Hadi, Gholamreza Askari, Fariborz Khorvash, Arman Arab
Summary: This study evaluated the association between diet quality and migraine outcomes. The results showed that improved diet quality was associated with lower migraine frequency, severity, and migraine-related disability. Further research is needed to confirm these findings and explore the causal mechanisms.
NUTRITIONAL NEUROSCIENCE
(2023)
