Article
Environmental Sciences
Lays de Oliveira Goncalves Alho, Renan Castelhano Gebara, Adrislaine da Silva Mansano, Giseli Swerts Rocha, Maria da Graca Gama Melao
Summary: This study investigated the effects of manganese (Mn), chromium (Cr), and their mixtures on freshwater Chlorophyceae. The results showed that Mn was more toxic to the microalgae compared to Cr, and the species exhibited a high sensitivity to Mn. The tested metals significantly decreased algal growth and chlorophyll a fluorescence, indicating an impact on pigment synthesis. The mixture tests revealed additive effects of Mn and Cr.
ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY
(2022)
Article
Marine & Freshwater Biology
Renan Castelhano Gebara, Lays de Oliveira Gondalves Alho, Adrislaine da Silva Mansano, Giseli Swerts Rocha, Maria da Grada Gama Melao
Summary: Increasing metal concentrations in aquatic environments, mainly caused by human actions, pose a concern for the biodiversity of aquatic biota. This study tested the effects of zinc and aluminum mixtures on a green microalga's photosynthetic apparatus using PAM fluorometry. The results showed that different concentrations of the metals had synergistic or antagonistic effects on the algae's growth and photosynthetic parameters. It is important to consider mixture toxicity tests in risk assessments for green algae, as the effects are more than additive or less than additive.
AQUATIC TOXICOLOGY
(2023)
Article
Environmental Sciences
Yufan Nie, Zikang Wang, Simin Yu, Yuping Liu, Luyao Zhang, Rui Liu, Zhiqiang Zhou, Wentao Zhu, Jinling Diao
Summary: Chemical pollution and high temperature have negative effects on the adaptability of lizards, affecting their behavior, physiology, and overall survival. Lizards employ adaptive strategies such as up-regulating detoxification enzymes, increasing body temperature preference, and increasing food intake to mitigate the impacts of chemical pollutants. Additionally, lizards show adaptation to high temperature through elevated Hsp70 levels and increased food intake. However, the combined effects of chemical pollution and high temperature result in more severe behavioral disorders and oxidative stress, posing a threat to the long-term survival and sustainability of lizard populations.
SCIENCE OF THE TOTAL ENVIRONMENT
(2022)
Article
Marine & Freshwater Biology
Larissa Luiza dos Reis, Lays de Oliveira Goncalves Alho, Cinthia Bruno de Abreu, Renan Castelhano Gebara, Adrislaine da Silva Mansano, Maria da Graca Gama Melao
Summary: This study evaluated the effects of cadmium and cobalt on a microalgae species and found that they significantly affected the algae's growth and photosynthetic performance. The metal mixture showed both synergistic and antagonistic interactions, depending on the concentrations.
AQUATIC TOXICOLOGY
(2022)
Article
Environmental Sciences
Tina Elersek, Tilen Notersberg, Ana Kovacic, Ester Heath, Metka Filipic
Summary: The study found that S. leopoliensis is more sensitive to BPA and BPF, with both showing comparable toxic potential and similar hazard to phytoplankton. In different concentration ranges, additive effect was observed in P. subcapitata with BPA, while no pronounced combined effect was seen in S. leopoliensis. Comparison suggests that in certain industrial areas, BPA may pose an environmental risk, while BPF does not.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2021)
Review
Chemistry, Inorganic & Nuclear
Nahyun Kwon, Dayeh Kim, K. M. K. Swamy, Juyoung Yoon
Summary: Reactive oxygen species (ROS) and reactive nitrogen species (RNS) play crucial roles in human life, but overproduction can lead to cell damage and diseases. Researchers have developed fluorescent and luminescent probes based on metal-coordinated systems to detect and image these active species, providing valuable tools for studying their roles in signaling and pathology.
COORDINATION CHEMISTRY REVIEWS
(2021)
Article
Biochemistry & Molecular Biology
Qiuhua Wang, Xiaodong Xie, Qi Chen, Shouli Yi, Jiaji Chen, Qi Xiao, Meiling Yu, Yingyi Wei, Tingjun Hu
Summary: This study found that quercitrin can decrease the secretion of reactive oxygen species induced by PRV infection. It also identified differentially expressed RNA involved in cell metabolism, protein phosphorylation, and antioxidation. The study provides a scientific foundation for understanding the role of quercitrin in combating virus-induced oxidative stress.
Article
Environmental Sciences
Savinda Heshani Arambawatta-Lekamge, Asoka Pathiratne, I. Vayanga Nishani Rathnayake
Summary: This study aimed to generate freshwater ecotoxicity data for Cd and Cu in tropical temperature exposures, and derive ecotoxicity thresholds (PC) based on 'tropical temperature-specific exposure' data. The results showed that Moina macrocopa was the most sensitive species to both metals, while Chlorella vulgaris and Lemna perpusilla showed highest tolerance to Cd and Cu, respectively. The derived PC values for Cd and Cu provide insight into the protection of tropical freshwater life under chronic exposure.
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
(2021)
Article
Environmental Sciences
Vienna Delnat, Julie Verheyen, Ine Van Hileghem, Robby Stoks
Summary: Despite the surging interest in the interactions between toxicants and non-chemical stressors, we have poor knowledge whether these patterns differ among genotypes within a population. Warming and toxicants are two widespread stressors in aquatic systems that are known to modify each other's effects. We studied to what extent effects of sequential exposure to a heat spike and the pesticide esfenvalerate differed among genotypes in the water flea Daphnia magna. Esfenvalerate had similar negative effects on survival and body size across genotypes, and for most genotypes it increased time to maturation, yet the effects on the reproductive performance were only detected in some genotypes and were inconsistent in direction. Across genotypes, the heat spike increased the heat tolerance, yet the negative effects of the heat spike on survival, reproductive performance and body size, and the positive effects on grazing rate and the shortened time to maturation were only seen in some genotypes. Notably, the interaction type between both stressors differed among genotypes. In contrast to our expectation, the impact of esfenvalerate was only magnified by the heat spike in some genotypes and only for a subset of the traits. For survival and time to maturation, the interaction type for the same stressor combination covered all three categories: additions, synergisms and antagonisms. This illustrates that categorizing the interaction type between stressors at the level of populations may hide considerable intrapopulation variation among genotypes. Opposite to our expectation, the more pesticide-tolerant genotypes showed a stronger synergism between both stressors. Genotype-dependent interaction patterns between toxicants and non-chemical stressors may explain inconsistencies among studies and challenges ecological risk assessment based on single genotypes. The observed genetic differences in the responses to the (combined) stressors may fuel the evolution of the stressor interaction pattern, a largely ignored topic in evolutionary ecotoxicology.
ENVIRONMENTAL POLLUTION
(2022)
Article
Environmental Sciences
Samarth Sharma, Padmaja Rai, Ved Prakash, Sneha Tripathi, Kavita Tiwari, Neeraj Gahlawat, Durgesh Kumar Tripathi, Shivesh Sharma
Summary: The hyperaccumulation of heavy metals in agricultural land has become a global concern, affecting the yield of important crops and food security. This study explores the role of exogenous application of sodium nitroprusside (SNP) and silicon (Si) in mitigating the detrimental effects of chromium (Cr) toxicity in Brassica juncea. The combined application of Si and SNP shows significant alleviatory effects by regulating ROS accumulation and enhancing antioxidant metabolism.
ENVIRONMENTAL POLLUTION
(2023)
Article
Multidisciplinary Sciences
Na Kong, Hanjie Zhang, Chan Feng, Chuang Liu, Yufen Xiao, Xingcai Zhang, Lin Mei, Jong Seung Kim, Wei Tao, Xiaoyuan Ji
Summary: The regulation of intracellular ROS levels is crucial for cellular homeostasis and fate determination, with moderate levels promoting cell proliferation and differentiation, and excessive levels inducing apoptosis. Surface-oxidized arsenene nanosheets with engineered modifications serve as an intelligent theranostic platform for cancer therapy, enabling targeted delivery and prolonged circulation for effective treatment.
NATURE COMMUNICATIONS
(2021)
Article
Environmental Sciences
Sagan Leggett, Jonathan Borrelli, Devin K. Jones, Rick Relyea
Summary: Chemical pollution may have an impact on animal sex ratios, but its effects are smaller compared to biological stressors.
ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY
(2021)
Article
Engineering, Electrical & Electronic
Xiaolong Wang, Jun Liu, Quanxin Li, Lian Li, Shanrui Li, Yunhan Ding, Tong Zhao, Ying Sun, Yuantao Zhang
Summary: Recently, the use of cold atmospheric plasma (CAP) in liquid treatment has gained attention for its medical efficacy. It has been shown that CAP can enhance the biological activity of vegetable oils by generating reactive species. Optimizing reactor parameters is important in controlling the activity of plasma-activated oil for better biological effects.
Review
Biochemistry & Molecular Biology
Kaiser Iqbal Wani, M. Naeem, Christian Danve M. Castroverde, Hazem M. Kalaji, Mohammed Albaqami, Tariq Aftab
Summary: Abiotic stressors such as drought, heavy metals, and high salinity are causing significant crop losses globally. To meet the increasing demand for food, it is crucial to prevent global crop losses. Nitric oxide, as a reactive gaseous signaling molecule, plays a crucial role in plant development and responses to stressors.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Article
Environmental Sciences
Charlotte Philippe, Eli S. J. Thore, Sebastiaan Verbesselt, Arnout F. Gregoir, Luc Brendonck, Tom Pinceel
Summary: Global warming and environmental pollution pose threats to aquatic ecosystems. The interactive effects of these stressors can have greater impacts than expected. A study using a fish model found that exposure to a pesticide and a temperature increase had separate and combined effects on fitness-related endpoints. These findings suggest that climate change may worsen the impact of environmental pollution, and the interactive effects of chronic exposure to multiple stressors should be considered.
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
(2022)
Article
Environmental Sciences
Cinthia Bruno de Abreu, Renan Castelhano Gebara, Larissa Luiza dos Reis, Giseli Swerts Rocha, Lays de Oliveira Goncalves Alho, Lais Mendes Alvarenga, Luciano Sindra Virtuoso, Marcelo Assis, Adrislaine da Silva Mansano, Elson Longo, Maria da Graca Gama Melao
Summary: Silver tungstate (α-Ag2WO4) in cube and rod morphologies exhibit toxicity to microalgae, reducing cellular complexity and chlorophyll a fluorescence. The rod morphology is more toxic than the cube morphology, with different levels of silver ion release.
Article
Environmental Sciences
Lays de Oliveira Goncalves Alho, Renan Castelhano Gebara, Adrislaine da Silva Mansano, Giseli Swerts Rocha, Maria da Graca Gama Melao
Summary: This study investigated the effects of manganese (Mn), chromium (Cr), and their mixtures on freshwater Chlorophyceae. The results showed that Mn was more toxic to the microalgae compared to Cr, and the species exhibited a high sensitivity to Mn. The tested metals significantly decreased algal growth and chlorophyll a fluorescence, indicating an impact on pigment synthesis. The mixture tests revealed additive effects of Mn and Cr.
ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY
(2022)
Article
Marine & Freshwater Biology
Larissa Luiza dos Reis, Lays de Oliveira Goncalves Alho, Cinthia Bruno de Abreu, Renan Castelhano Gebara, Adrislaine da Silva Mansano, Maria da Graca Gama Melao
Summary: This study evaluated the effects of cadmium and cobalt on a microalgae species and found that they significantly affected the algae's growth and photosynthetic performance. The metal mixture showed both synergistic and antagonistic interactions, depending on the concentrations.
AQUATIC TOXICOLOGY
(2022)
Article
Environmental Sciences
Juliane Silberschmidt Freitas, Thandy Junio da Silva Pinto, Maria Paula Cardoso Yoshii, Lais Conceicao Menezes da Silva, Lais Fernanda de Palma Lopes, Allan Pretti Ogura, Lais Girotto, Cassiana Carolina Montagner, Lays de Oliveira Goncalves Alho, Renan Castelhano Gebara, Luis Schiesari, Evaldo Luiz Gaeta Espindola
Summary: Expansion of sugarcane crops in Brazil has potentially led to increased contamination of local habitats. This study found that sugarcane pesticides and fertilizer can have toxic effects on amphibians, including mortality and impairing physiological responses. The combination of pesticides resulted in more sublethal effects in tadpoles compared to individual pesticides.
ENVIRONMENTAL POLLUTION
(2022)
Article
Environmental Sciences
Cinthia Bruno de Abreu, Renan Castelhano Gebara, Larissa Luiza dos Reis, Giseli Swerts Rocha, Lays Oliveira Goncalves Alho, Lais Mendes Alvarenga, Luciano Sindra Virtuoso, Marcelo Assis, Adrislaine da Silva Mansano, Elson Longo, Maria da Graca Gama Melao
Summary: This study investigated the effects of α-Ag2WO4 on the freshwater algae Raphidocelis subcapitata. The results showed that α-Ag2WO4 significantly reduced cell density, photosynthetic activity, and chlorophyll a content. However, there was a possible recovery of photosynthetic activity in surviving cells after a certain period of time.
WATER AIR AND SOIL POLLUTION
(2022)
Article
Marine & Freshwater Biology
Renan Castelhano Gebara, Lays de Oliveira Gondalves Alho, Adrislaine da Silva Mansano, Giseli Swerts Rocha, Maria da Grada Gama Melao
Summary: Increasing metal concentrations in aquatic environments, mainly caused by human actions, pose a concern for the biodiversity of aquatic biota. This study tested the effects of zinc and aluminum mixtures on a green microalga's photosynthetic apparatus using PAM fluorometry. The results showed that different concentrations of the metals had synergistic or antagonistic effects on the algae's growth and photosynthetic parameters. It is important to consider mixture toxicity tests in risk assessments for green algae, as the effects are more than additive or less than additive.
AQUATIC TOXICOLOGY
(2023)
Article
Biotechnology & Applied Microbiology
Giseli Swerts Rocha, Christopher C. Parrish, Evaldo L. G. Espindola
Summary: This study evaluated the effects of nitrogen limitation and cadmium exposure on the photosynthetic parameters and lipid classes of Ankistrodesmus densus. The results showed that both nitrogen and cadmium had significant impacts on algal growth, chlorophyll a production, and lipid composition. The combined stressors had synergistic effects on various parameters, indicating their influence on algal physiology. However, the algae's photoprotective mechanisms effectively prevented photodamage.
JOURNAL OF APPLIED PHYCOLOGY
(2023)
Article
Environmental Sciences
Giseli Swerts Rocha, Lais Fernanda de Palma Lopes, Jessyca Ferreira de Medeiros, Cassiana C. Montagner, Evaldo Luiz Gaeta Espindola
Summary: Anthropogenic activities contribute to the contamination of water bodies, posing potential threats to the biota. The interaction between stressors and species determines the impact on organisms, with both antagonistic and synergistic responses observed. In this study, the response of freshwater copepod Notodiaptomus iheringi to Cd and fipronil was evaluated, revealing adverse effects on survival, egg production, and hatching. The Cd-fipronil combination showed antagonistic effects on survival and egg production, while synergistic effects were observed in egg hatching. These findings emphasize the challenges in managing the interaction between pollutants and highlight the sensitivity of N. iheringi to chemical mixtures.
ENVIRONMENTAL POLLUTION
(2023)
Article
Environmental Sciences
Lais Fernanda de Palma Lopes, Giseli Swerts Rocha, Jessyca Ferreira de Medeiros, Cassiana Carolina Montagner, Evaldo Luiz Gaeta Espindola
Summary: The study aimed to evaluate the effects of pesticides, fipronil and 2,4-D, individually and in mixture, on the copepod species N. iheringi. It was found that both pesticides had acute toxicity to the copepods, and the mixture of the pesticides had synergistic effects on their mortality. However, there were no differences in mortality and feeding rate between the treatment groups and the control group within 4 hours after exposure.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2023)
Article
Environmental Sciences
Uriel Arreguin-Rebolledo, Renan Castelhano Gebara, Gladys Valencia-Castaneda, Roberto Rico-Martinez, Martin G. Frias-Espericueta, Elson Longo, Federico Paez-Osuna
Summary: Data is lacking on the effects of binary metal mixtures on marine zooplankton, especially rotifers. This study examined the toxicity of 21 equitoxic binary mixtures of As, Cd, Cu, Fe, Hg, Pb, and Zn on the euryhaline rotifer Proales similis. The results showed that the majority of these mixtures exhibited synergistic effects, highlighting the need for revising protection guidelines for marine biota.
MARINE POLLUTION BULLETIN
(2024)
Article
Multidisciplinary Sciences
Francieli F. Bomfim, Maria G. G. Melao, Renan C. Gebara, Fabio A. Lansac-Toha
Summary: Temperature rise affects the metabolic rates, life-history parameters, and feeding behavior of C. silvestrii. It enhances assimilation and secondary production rates but decreases filtration and ingestion rates. The increase in temperature also leads to changes in reproductive performance and development time. At intermediate temperatures, C. silvestrii may become an important food resource, while at the highest temperature, the metabolic processes are stressed, resulting in decreased assimilation and secondary production.
ANAIS DA ACADEMIA BRASILEIRA DE CIENCIAS
(2022)
