Late‐Stage 18 O Labeling of Primary Sulfonamides via a Degradation–Reconstruction Pathway

NHC-Catalyzed Deamination of Primary Sulfonamides: A Platform for Late-Stage Functionalization

(2019) Patrick S. Fier et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Carboxylesterase catalyzed 18O-labeling of carboxylic acid and its potential application in LC-MS/MS based quantification of drug metabolites

(2019) Zaikuan J. Yu et al.   Drug Metabolism and Pharmacokinetics

Sulfa drug analogs: new classes of N-sulfonyl aminated azines and their biological and preclinical importance in medicinal chemistry (2000–2018)

(2019) Galal H. Elgemeie et al.   MEDICINAL CHEMISTRY RESEARCH

Deuterium- and Tritium-Labelled Compounds: Applications in the Life Sciences

(2018) Jens Atzrodt et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

34 S: A New Opportunity for the Efficient Synthesis of Stable Isotope Labeled Compounds

(2018) Sumei Ren et al.   CHEMISTRY-A EUROPEAN JOURNAL

The hydrogen atom transfer reactivity of sulfinic acids

(2018) Markus Griesser et al.   Chemical Science

Isotope labelling by reduction of nitriles: Application to the synthesis of isotopologues of tolmetin and celecoxib

(2017) Kate Ellis-Sawyer et al.   JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS

A General, One-Pot Method for the Synthesis of Sulfinic Acids from Methyl Sulfones

(2016) Donald R. Gauthier et al.   ORGANIC LETTERS

Isotope chemistry; a useful tool in the drug discovery arsenal

(2015) Charles S. Elmore et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Sulfonamide formation from sodium sulfinates and amines or ammonia under metal-free conditions at ambient temperature

(2015) Kai Yang et al.   GREEN CHEMISTRY

Absolute bioavailability of evacetrapib in healthy subjects determined by simultaneous administration of oral evacetrapib and intravenous [13C8]-evacetrapib as a tracer

(2015) Ellen A. Cannady et al.   JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS

Beyond C, H, O, and N! Analysis of the Elemental Composition of U.S. FDA Approved Drug Architectures

(2014) Brandon R. Smith et al.   JOURNAL OF MEDICINAL CHEMISTRY

Iridium-Catalyzed C–H Activation and Deuteration of Primary Sulfonamides: An Experimental and Computational Study

(2014) William J. Kerr et al.   ACS Catalysis

A stable isotope-labeled internal standard is essential for correcting for the interindividual variability in the recovery of lapatinib from cancer patient plasma in quantitative LC–MS/MS analysis

(2013) Jianmei Wu et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

Data-Mining for Sulfur and Fluorine: An Evaluation of Pharmaceuticals To Reveal Opportunities for Drug Design and Discovery

(2013) Elizabeth A. Ilardi et al.   JOURNAL OF MEDICINAL CHEMISTRY

Practical and Efficient Strategy for Evaluating Oral Absolute Bioavailability with an Intravenous Microdose of a Stable Isotopically-Labeled Drug Using a Selected Reaction Monitoring Mass Spectrometry Assay

(2012) Hao Jiang et al.   ANALYTICAL CHEMISTRY

Peptide and Protein Quantitation by Acid-Catalyzed 18O-Labeling of Carboxyl Groups

(2011) Erik Haaf et al.   ANALYTICAL CHEMISTRY

Acid-Catalyzed Oxygen-18 Labeling of Peptides

(2009) Richard Niles et al.   ANALYTICAL CHEMISTRY

Application of Stable Isotope-Labeled Compounds in Metabolism and in Metabolism-Mediated Toxicity Studies

(2008) Abdul E. Mutlib   CHEMICAL RESEARCH IN TOXICOLOGY

Naturally occurring isotopes of an analyte can interfere with doubly deuterated internal standard measurement

(2008) K Duxbury et al.   ANNALS OF CLINICAL BIOCHEMISTRY