Deep Eutectic Solvents as Media in Alcohol Dehydrogenase‐Catalyzed Reductions of Halogenated Ketones

Deep eutectic solvents for redox biocatalysis

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Ultrafast Iron-Catalyzed Reduction of Functionalized Ketones: Highly Enantioselective Synthesis of Halohydrines, Oxaheterocycles, and Aminoalcohols

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Discovery of a Switch Between Prelog and Anti-Prelog Reduction toward Halogen-Substituted Acetophenones in Short-Chain Dehydrogenase/Reductases

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Novel Insights into the Combination of Metal- and Biocatalysis: Cascade One-Pot Synthesis of Enantiomerically Pure Biaryl Alcohols in Deep Eutectic Solvents

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Preparation of Structurally Diverse Chiral Alcohols by Engineering Ketoreductase CgKR1

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Unveiling the Hidden Performance of Whole Cells in the Asymmetric Bioreduction of Aryl-containing Ketones in Aqueous Deep Eutectic Solvents

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Effective Biotransformation of Ethyl 4-Chloro-3-Oxobutanoate into Ethyl (S)-4-Chloro-3-Hydroxybutanoate by Recombinant E. coli CCZU-T15 Whole Cells in [ChCl][Gly]–Water Media

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Structure-guided stereoselectivity inversion of a short-chain dehydrogenase/reductase towards halogenated acetophenones

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Deep Eutectic Solvents: The Organic Reaction Medium of the Century

(2016) Diego A. Alonso et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

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Preparation of enantiomerically enriched aromatic β-hydroxynitriles and halohydrins by ketone reduction with recombinant ketoreductase KRED1-Pglu

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Engineering of Candida glabrata Ketoreductase 1 for Asymmetric Reduction of α-Halo Ketones

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Combination of deep eutectic solvent and ionic liquid to improve biocatalytic reduction of 2-octanone with Acetobacter pasteurianus GIM1.158 cell

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Redesigning alcohol dehydrogenases/reductases for more efficient biosynthesis of enantiopure isomers

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Performance of Recombinant-Whole-Cell-Catalyzed Reductions in Deep-Eutectic-Solvent-Aqueous-Media Mixtures

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Modularized Biocatalysis: Immobilization of Whole Cells for Preparative Applications in Microaqueous Organic Solvents

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Deep Eutectic Solvents for Organocatalysis, Biotransformations, and Multistep Organocatalyst/Enzyme Combinations

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Identification of key residues in Debaryomyces hansenii carbonyl reductase for highly productive preparation of (S)-aryl halohydrins

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Lyophilized Rhodotorula yeast as all-in-one redox biocatalyst: Access to enantiopure building blocks by simple chemoenzymatic one-pot procedures

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Scaling-Up of “Smart Cosubstrate” 1,4-Butanediol Promoted Asymmetric Reduction of Ethyl-4,4,4-trifluoroacetoacetate in Organic Media

(2015) Ralf Zuhse et al.   ORGANIC PROCESS RESEARCH & DEVELOPMENT

Baker’s yeast-mediated asymmetric reduction of ethyl 3-oxobutanoate in deep eutectic solvents

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Controlling Substrate Specificity and Stereospecificity of Alcohol Dehydrogenases

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Enantioselective bioreductive preparation of chiral halohydrins employing two newly identified stereocomplementary reductases

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Enhancing Asymmetric Reduction of 3-Chloropropiophenone with Immobilized Acetobacter sp. CCTCC M209061 Cells by Using Deep Eutectic Solvents as Cosolvents

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Whole-Cell Teabag Catalysis for the Modularisation of Synthetic Enzyme Cascades in Micro-Aqueous Systems

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Whole-Cell Biocatalysis in Deep-Eutectic-Solvents/Aqueous Mixtures

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Deep Eutectic Solvents (DESs) and Their Applications

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Natural Deep Eutectic Solvents – Solvents for the 21st Century

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Synthesis of Enantiopure Fluorohydrins Using Alcohol Dehydrogenases at High Substrate Concentrations

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Deep eutectic solvents: syntheses, properties and applications

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Asymmetric reduction of ketones with recombinant E. coli whole cells in neat substrates

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Asymmetric Chemoenzymatic Synthesis of Miconazole and Econazole Enantiomers. The Importance of Chirality in Their Biological Evaluation

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Chemo- and Stereodivergent Preparation of Terminal Epoxides and Bromohydrins through One-Pot Biocatalysed Reactions: Access to Enantiopure Five- and Six-Membered N-Heterocycles

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Ketone-Alcohol Hydrogen-Transfer Equilibria: Is the Biooxidation of Halohydrins Blocked?

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Tandem Concurrent Processes: One-Pot Single-Catalyst Biohydrogen Transfer for the Simultaneous Preparation of Enantiopure Secondary Alcohols

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An Exceptionally DMSO-Tolerant Alcohol Dehydrogenase for the Stereoselective Reduction of Ketones

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One-Way Biohydrogen Transfer for Oxidation ofsec-Alcohols

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