Conversion of effector CD4+ T cells to a CD8+ MHC II-recognizing lineage

Key roles of autophagy in regulating T-cell function

(2016) Yair Botbol et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Antiviral CD8 + T Cells Restricted by Human Leukocyte Antigen Class II Exist during Natural HIV Infection and Exhibit Clonal Expansion

(2016) Srinika Ranasinghe et al.   IMMUNITY

Broadly targeted CD8+ T cell responses restricted by major histocompatibility complex E

(2016) S. G. Hansen et al.   SCIENCE

A Subset of CD4/CD8 Double-Negative T Cells Expresses HIV Proteins in Patients on Antiretroviral Therapy

(2015) Laura K. DeMaster et al.   JOURNAL OF VIROLOGY

CD14-expressing cancer cells establish the inflammatory and proliferative tumor microenvironment in bladder cancer

(2015) Ming T. Cheah et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Diversity index of mucosal resident T lymphocyte repertoire predicts clinical prognosis in gastric cancer

(2015) Qingzhu Jia et al.   OncoImmunology

Roles of autophagy in HIV infection

(2014) Christina Dinkins et al.   IMMUNOLOGY AND CELL BIOLOGY

CD4+ T cell lineage integrity is controlled by the histone deacetylases HDAC1 and HDAC2

(2014) Nicole Boucheron et al.   NATURE IMMUNOLOGY

Double Negative (DN) [CD3(+)CD4(−)CD8(−)] T cells correlate with disease progression during HIV infection

(2013) Qi Liang et al.   IMMUNOLOGICAL INVESTIGATIONS

Impaired Autophagy, Defective T Cell Homeostasis, and a Wasting Syndrome in Mice with a T Cell-Specific Deletion of Vps34

(2013) V. V. Parekh et al.   JOURNAL OF IMMUNOLOGY

Transcriptional reprogramming of mature CD4+ helper T cells generates distinct MHC class II–restricted cytotoxic T lymphocytes

(2013) Daniel Mucida et al.   NATURE IMMUNOLOGY

Mutual expression of the transcription factors Runx3 and ThPOK regulates intestinal CD4+ T cell immunity

(2013) Bernardo Sgarbi Reis et al.   NATURE IMMUNOLOGY

Cytomegalovirus Vectors Violate CD8+ T Cell Epitope Recognition Paradigms

(2013) S. G. Hansen et al.   SCIENCE

CD4 CTL: Living up to the challenge

(2013) Hilde Cheroutre et al.   SEMINARS IN IMMUNOLOGY

CD4–CD8 differentiation in the thymus: connecting circuits and building memories

(2012) Yumei Xiong et al.   CURRENT OPINION IN IMMUNOLOGY

Impairment of CD4+cytotoxic T cells predicts poor survival and high recurrence rates in patients with hepatocellular carcinoma

(2012) Junliang Fu et al.   HEPATOLOGY

CD4+CD8+ T Cells Represent a Significant Portion of the Anti-HIV T Cell Response to Acute HIV Infection

(2012) M. A. Frahm et al.   JOURNAL OF IMMUNOLOGY

Dynamics of CD4+ T Cell Responses against Listeria monocytogenes

(2012) F. Graw et al.   JOURNAL OF IMMUNOLOGY

HIV gag-specific immune response mediated by double negative (CD3+CD4−CD8−) T cells in HIV-exposed seronegative individuals

(2012) Clara Restrepo et al.   JOURNAL OF MEDICAL VIROLOGY

Study of CD4+CD8+ Double positive T-lymphocyte phenotype and function in Indian patients infected with HIV-1

(2012) Neeraj K. Chauhan et al.   JOURNAL OF MEDICAL VIROLOGY

Distinct CD4+ helper T cells involved in primary and secondary responses to infection

(2012) K. S. Weber et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Canonical autophagy dependent on the class III phosphoinositide-3 kinase Vps34 is required for naive T-cell homeostasis

(2012) T. Willinger et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Level of double negative T cells, which produce TGF-β and IL-10, predicts CD8 T-cell activation in primary HIV-1 infection

(2011) Gaël Petitjean et al.   AIDS

CD3+CD4−CD8− (double negative) T cells: Saviours or villains of the immune response?

(2011) Fulvio D’Acquisto et al.   BIOCHEMICAL PHARMACOLOGY

CX3CR1 drives cytotoxic CD4+CD28− T cells into the brain of multiple sclerosis patients

(2011) Bieke Broux et al.   JOURNAL OF AUTOIMMUNITY

The Class III Kinase Vps34 Promotes T Lymphocyte Survival through Regulating IL-7Rα Surface Expression

(2011) Ian X. McLeod et al.   JOURNAL OF IMMUNOLOGY

The network of transcription factors that underlie the CD4 versus CD8 lineage decision

(2010) T. Naito et al.   INTERNATIONAL IMMUNOLOGY

The zinc-finger protein MAZR is part of the transcription factor network that controls the CD4 versus CD8 lineage fate of double-positive thymocytes

(2010) Shinya Sakaguchi et al.   NATURE IMMUNOLOGY

From a Global View to Focused Examination: Understanding Cellular Function of Lipid Kinase VPS34-Beclin 1 Complex in Autophagy

(2010) Z. Yue et al.   Journal of Molecular Cell Biology

Phenotypic and Functional Characterization of HIV-1-Specific CD4+CD8+ Double-Positive T Cells in Early and Chronic HIV-1 Infection

(2009) Rawleigh Howe et al.   JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES

Thymic OX40 Expression Discriminates Cells Undergoing Strong Responses to Selection Ligands

(2009) M. Klinger et al.   JOURNAL OF IMMUNOLOGY

Autophagy Is Essential for Mitochondrial Clearance in Mature T Lymphocytes

(2009) H. H. Pua et al.   JOURNAL OF IMMUNOLOGY

CD4 downregulation by memory CD4+ T cells in vivo renders African green monkeys resistant to progressive SIVagm infection

(2009) Coreen M Beaumier et al.   NATURE MEDICINE

The regulation and function of Class III PI3Ks: novel roles for Vps34

(2008) Jonathan M. Backer   BIOCHEMICAL JOURNAL

Human immunodeficiency virus-1 acquisition in genital mucosa: Langerhans cells as key-players

(2008) M. A. W. P. de Jong et al.   JOURNAL OF INTERNAL MEDICINE

Beclin 1 Forms Two Distinct Phosphatidylinositol 3-Kinase Complexes with Mammalian Atg14 and UVRAG

(2008) Eisuke Itakura et al.   MOLECULAR BIOLOGY OF THE CELL