4.7 Editorial Material

Emerging from the Shadow of Hemagglutinin: Neuraminidase Is an Important Target for Influenza Vaccination

Journal

CELL HOST & MICROBE
Volume 26, Issue 6, Pages 712-713

Publisher

CELL PRESS
DOI: 10.1016/j.chom.2019.11.006

Keywords

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Funding

  1. National Institute of Allergy and Infectious Disease (NIAID) Collaborative Influenza Vaccine Innovation Centers (CIVIC) [75N93019C00051]
  2. NIAID Centers of Excellence for Influenza Research and Surveillance (CEIRS) [HHSN272201400005C, HHSN272201400008C]
  3. NIAID [AI117287, AI128821, U19AI082724, U19AI109946, U19AI057266]

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Gilchuk et al. (2019) and Zhu et al. (2019) provide detailed structural information about epitopes on influenza virus N9 neuraminidase and characterize breadth, potency, mechanism of action, and in vivo protective effects of human antibodies targeting these epitopes. The findings highlight the importance of neuraminidase as a target for improved influenza virus vaccines.

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