Article
Orthopedics
Jesus M. Villa, Tejbir S. Pannu, Ibrahim Theeb, Martin A. Buttaro, Jose Onativia, Lisandro Carbo, Daniel H. Rienzi, Jose Fregeiro, Nikolai N. Kornilov, Svetlana A. Bozhkova, Nemandra A. Sandiford, Nicolas S. Piuzzi, Carlos A. Higuera, Daniel O. Kendoff
Summary: The most common pathogens for periprosthetic joint infections were Staphylococcus aureus and Staphylococcus epidermidis. The US and the UK had the lowest rates of resistant organisms, while Germany and Russia had the highest. The UK and Uruguay had the lowest rates of polymicrobial infections.
JOURNAL OF ARTHROPLASTY
(2021)
Review
Medicine, General & Internal
Christos Koutserimpas, Symeon Naoum, Vasileios Giovanoulis, Konstantinos Raptis, Kalliopi Alpantaki, Konstantinos Dretakis, Georgia Vrioni, George Samonis
Summary: Fungal hip prosthetic joint infections (PJIs) are rare but severe infections. This review analyzed all published cases of fungal hip PJIs to provide comprehensive information on demographics, causative fungi, treatment options, and infection outcomes.
Article
Orthopedics
Amit S. Piple, Jennifer C. Wang, Kareem J. Kebaish, Emily S. Mills, Daniel A. Oakes, Jay R. Lieberman, Alexander B. Christ, Nathanael D. Heckmann
Summary: This study aimed to assess the relationship between prednisone dosage and rates of periprosthetic joint infection (PJI) following total joint arthroplasty (TJA). The study found that patients receiving prednisone therapy were at increased risk of PJI and sepsis, but no dose-dependent relationship between prednisone and infectious complications was identified.
JOURNAL OF ARTHROPLASTY
(2023)
Article
Orthopedics
Ajay Premkumar, David A. Kolin, Kevin X. Farley, Jacob M. Wilson, Alexander S. McLawhorn, Michael B. Cross, Peter K. Sculco
Summary: Based on the latest data, the annual hospital costs related to PJI of the hip and knee are estimated to reach $1.85 billion by 2030. The growth in costs is mainly due to increases in volume, while the incidence of PJI and cost per case remained relatively constant from 2002 to 2017. Efforts to develop effective preventive strategies are urgently needed to reduce rates of PJI after total hip and knee arthroplasty.
JOURNAL OF ARTHROPLASTY
(2021)
Article
Medicine, General & Internal
Wen-Chi Su, Yu-Chin Lai, Cheng-Hung Lee, Cheng-Min Shih, Chao-Ping Chen, Li-Ling Hung, Shun-Ping Wang
Summary: This study aimed to investigate the effectiveness of preoperative bathing with chlorhexidine gluconate in reducing postoperative periprosthetic joint infection (PJI) rates after total hip arthroplasty (THA). The study included 933 primary THA patients, with no statistically significant differences in age, sex, or operated side between the group that underwent chlorhexidine bathing and the control group. While PJI cases were more common in the control group, the difference was not statistically significant.
JOURNAL OF CLINICAL MEDICINE
(2021)
Review
Orthopedics
Navin Fernando, Steven Yacovelli, Javad Parvizi
Summary: The incidences of periprosthetic fracture and periprosthetic joint infection after total hip arthroplasty are expected to increase exponentially. It is suggested that there is a possibility of coexistence of periprosthetic fracture and infection, particularly in patients with a loose femoral implant and high pretest possibility. Limited literature is available for guidance on managing this complex issue.
JOURNAL OF THE AMERICAN ACADEMY OF ORTHOPAEDIC SURGEONS
(2022)
Article
Medicine, General & Internal
Alberto Delgado-Gonzalez, Juan Jose Morales-Viaji, Guillermo Criado-Albillos, Adoracion del Pilar Martin-Rodriguez, Josefa Gonzalez-Santos, Remedios Lopez-Liria, Carla Collazo-Riobo, Raul Soto-Camara, Jeronimo J. Gonzalez-Bernal
Summary: Retrospective study found that patients with patellar replacement, surgeries performed by experienced surgeons, male patients, and those with longer surgery or hospital stays were at a higher risk of infection after TKA. Patellar replacement may be a factor of infection but should be confirmed with randomized clinical trials. Close monitoring of patients with longer surgeries or hospital stays is suggested for early detection and proper treatment of infections.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Orthopedics
Mathew J. Whittaker, Prerna Arora, James I. Huddleston III, Stuart B. Goodman, William J. Maloney, Derek F. Amanatullah
Summary: It is unclear if extended trochanteric osteotomy (ETO) is effective in the setting of periprosthetic joint infection (PJI). Concerns exist regarding persistent infection with cerclage fixation, but limited evidence supports this theory. The study found no significant differences in operative time, blood loss, rate of repeat revision surgery, or postoperative complications between retaining or exchanging cerclage fixation in PJI patients. ETO remains a powerful tool for femoral component revision even in the presence of PJI.
JOURNAL OF ARTHROPLASTY
(2023)
Article
Orthopedics
David Kugelman, Mackenzie Roof, Alexander Egol, Isabella Guanche, Antonia F. Chen, Ran Schwarzkopf, Vinay K. Aggarwal
Summary: This study compared the outcomes of real-component (RC) and all-cement (AC) articulating spacers for total hip arthroplasty (THA) periprosthetic joint infection (PJI) treatment. The RC group showed shorter hospital stays and higher likelihood of being discharged home compared to the AC group, with no significant differences in reinfection and reoperation rates between the two spacer constructs.
JOURNAL OF ARTHROPLASTY
(2022)
Article
Orthopedics
Robert A. McCulloch, Antony J. Palmer, James Donaldson, Benjamin J. Kendrick, Jonathan Miles, Adrian Taylor
Summary: This study retrospectively analyzed patients with fungal periprosthetic joint infection (PJI) who underwent revision surgery at two high-volume arthroplasty centers. The study found that less than half of the patients achieved eradication of fungal PJI, and the outcomes were comparable for total knee arthroplasty (TKA) and total hip arthroplasty (THA). Most patients with fungal PJI presented with open wounds or a history of sinus disease.
JOURNAL OF ARTHROPLASTY
(2023)
Article
Medicine, General & Internal
Christopher W. Day, Kerry Costi, Susan Pannach, Gerald J. Atkins, Jochen G. Hofstaetter, Stuart A. Callary, Renjy Nelson, Donald W. Howie, Lucian B. Solomon
Summary: This study aimed to evaluate the effect of staged revision surgery on the rate of infection resolution and the functional outcomes and mortality rate at ten years for patients with periprosthetic joint infection (PJI). The results showed that most patients achieved infection resolution after multiple surgeries, with improved functional outcomes and pain. However, the ten-year mortality rate was higher than that of the general population.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Orthopedics
Xiaolei Ren, Lin Ling, Lin Qi, Zhongyue Liu, Wenchao Zhang, Zhimin Yang, Wanchun Wang, Chao Tu, Zhihong Li
Summary: High BMI, DM, AVN, femoral neck fracture, RA, CVD, CPD, neurological disease, opioid use, and IDA are individual-related risk factors for PJI after primary THA; female gender, dysplasia/dislocation, and OA are protective factors.
BMC MUSCULOSKELETAL DISORDERS
(2021)
Article
Orthopedics
Nicholas M. Hernandez, Michael W. Buchanan, Thorsten M. Seyler, Samuel S. Wellman, Jessica Seidelman, William A. Jiranek
Summary: 1.5-stage exchange arthroplasty may be a reasonable method to treat TKA PJI. At a mean follow-up of 2.7 years, there was an acceptable rate of infection recurrence and implant durability.
JOURNAL OF ARTHROPLASTY
(2021)
Article
Orthopedics
Lefko T. Charalambous, Colleen M. Wixted, Billy I. Kim, Niall H. Cochrane, Elshaday S. Belay, Hayden L. Joseph, Thorsten M. Seyler
Summary: This study investigated the factors influencing the costs of treating chronic peri-prosthetic joint infection (PJI) in patients. The study found that age, comorbidity index score, drug use, and surgical methods were associated with increased treatment costs. These findings can be used to improve reimbursement models and identify cost-saving measures.
JOURNAL OF ARTHROPLASTY
(2023)
Article
Orthopedics
Jeremy A. Dubin, Zhongming Chen, Sandeep S. Bains, Daniel Hameed, Michael A. Mont, Ronald E. Delanois, James Nace
Summary: This study found that a delay in total hip arthroplasty (THA) after septic arthritis is necessary to reduce the risk of post-THA periprosthetic joint infections (PJI). Patients who underwent THA within 0-6 months and 6-12 months after the diagnosis of septic arthritis had a 38 times and 22 times increased risk of post-THA PJI, respectively, compared to patients without a history of septic arthritis. Diabetes mellitus, obesity, and tobacco use were identified as risk factors for PJI in patients with a history of septic arthritis.
JOURNAL OF ARTHROPLASTY
(2023)
Article
Orthopedics
Bryn O. Zomar, Edward M. Vasarhelyi, Lyndsay E. Somerville, Brent A. Lanting, James L. Howard, Jacquelyn D. Marsh
Summary: In total knee arthroplasty for obese patients, patient-specific instrumentation (PSI) was found to be more costly and less effective compared to standard of care (SOC) from a healthcare payer perspective. However, from a societal perspective, PSI had an incremental cost-utility ratio of $11,230.00 per quality-adjusted life year gained, which was considered cost-effective.
JOURNAL OF ARTHROPLASTY
(2021)
Article
Orthopedics
Michael E. Neufeld, Brent A. Lanting, Michael Shehata, James L. Howard, Steven J. MacDonald, Matthew G. Teeter, Edward M. Vasarhelyi
Summary: This study found that the prevalence of unexpected positive cultures (UPCs) during presumed aseptic revision total hip arthroplasty is 9.2%, with encouraging infection-free implant survival rates in patients with UPC. Patients with single UPC who were not treated with antibiotics did not develop periprosthetic joint infections caused by the identified microorganism, suggesting that antibiotic treatment may not be necessary in all cases of UPC. Additionally, revision for adverse metal reaction was identified as a risk factor for subsequent infection-related failure in patients with UPC.
JOURNAL OF BONE AND JOINT SURGERY-AMERICAN VOLUME
(2021)
Article
Anesthesiology
E. Li
Summary: Surgical patients with peri-operative or recent SARS-CoV-2 infection are at increased risk of postoperative venous thromboembolism compared to those without a history of SARS-CoV-2. However, the optimal prophylaxis and treatment for venous thromboembolism in this patient population remains unknown. Venous thromboembolism is independently associated with 30-day mortality.
Article
Orthopedics
Jordan S. Broberg, Edward M. Vasarhelyi, Brent A. Lanting, James L. Howard, Matthew G. Teeter, Douglas D. R. Naudie
Summary: The study found no significant differences in implant migration or inducible displacement between the gap balancing and measured resection surgical techniques for bicruciate-stabilized total knee arthroplasty. This indicates that both surgical techniques are safe and effective options for implanting this specific implant design.
JOURNAL OF ARTHROPLASTY
(2022)
Article
Orthopedics
Jordan S. Broberg, Douglas D. R. Naudie, Brent A. Lanting, James L. Howard, Edward M. Vasarhelyi, Matthew G. Teeter
Summary: This study compared satisfied and dissatisfied total knee arthroplasty (TKA) patients and found no differences in implant migration and objectively measured function between the two groups. However, there were kinematic differences and differences in patient-reported outcome measures (PROMs). These findings suggest that improving the functional satisfaction of TKA requires restoration of kinematics in early flexion and management of patient's pain and expectations.
JOURNAL OF ARTHROPLASTY
(2022)
Article
Orthopedics
Michael E. Neufeld, Brent A. Lanting, Michael Shehata, Douglas D. R. Naudie, Richard W. McCalden, Matthew G. Teeter, Edward M. Vasarhelyi
Summary: The prevalence of unexpected positive intraoperative cultures (UPC) in presumed aseptic revision total knee arthroplasty (TKA) was found to be 9.8%, with excellent infection-free implant survival. The infection-free survivorship from prosthetic joint infection (PJI) caused by the same UPC microorganism is outstanding.
JOURNAL OF ARTHROPLASTY
(2022)
Article
Orthopedics
Mark J. Heidenreich, Brent A. Lanting, Richard W. McCalden, Douglas D. Naudie, James L. Howard, Steven J. MacDonald, Edward M. Vasarhelyi
Summary: Metaphyseal cones and sleeves offer equally durable survivorship in revision TKA, with periprosthetic joint infection being the most common mode of implant failure.
JOURNAL OF ARTHROPLASTY
(2022)
Article
Orthopedics
Eoghan Pomeroy, Niall P. McGoldrick, Patrick W. Moody, Edward M. Vasarhelyi, Richard W. McCalden, Brent A. Lanting
Summary: A comparative study was conducted to compare the stem alignment and cement mantle quality of collarless polished tapered cemented stems inserted through the direct anterior approach (DAA) and the direct lateral approach (DLA) for total hip arthroplasty. The results showed a higher incidence of coronal plane stem malalignment in the DAA group compared to the DLA group, while there was no difference in lateral stem alignment or cement mantle quality.
JOURNAL OF ARTHROPLASTY
(2022)
Article
Surgery
Jennifer S. Polus, Maxwell E. Perelgut, Edward M. Vasarhelyi, Matthew G. Teeter, Brent A. Lanting
Summary: This study compared the stability and migration of different femoral stem designs in direct lateral and direct anterior total hip arthroplasty. The results showed that the direct lateral group had less femoral stem migration compared to the direct anterior group. Migration was not correlated with function or activity.
CANADIAN JOURNAL OF SURGERY
(2022)
Article
Surgery
Jacquelyn Marsh, Ishita Joshi, Lyndsay Somerville, Edward Vasarhelyi, Brent Lanting
Summary: This study investigated the relationship between patient satisfaction and costs after total knee arthroplasty (TKA). The results showed that dissatisfied patients incurred higher costs in the first year after TKA, highlighting the importance of improving patient satisfaction and reducing the economic burden of TKA.
CANADIAN JOURNAL OF SURGERY
(2022)
Article
Anesthesiology
Yifan Li, S. Indu Singh, Edward Vasarhelyi, Javier Cubillos
Summary: This article discusses the use of point-of-care ultrasound in the postanesthesia care unit to diagnose acute arterial thrombosis after hip arthroplasty early and emphasizes the importance of this technique in facilitating timely intervention.
CANADIAN JOURNAL OF ANESTHESIA-JOURNAL CANADIEN D ANESTHESIE
(2022)
Article
Orthopedics
Allan R. Sekeitto, Jance G. McGale, Liam A. Montgomery, Edward M. Vasarhelyi, Ryan Willing, Brent A. Lanting
Summary: The thickness of the polyethylene insert in posterior-stabilized total knee arthroplasty affects the engagement of the post-cam mechanism, and understuffing and overstuffing have different effects on joint mechanics. Subtle changes in the polyethylene insert thickness alter the kinematics of the post-cam mechanism.
Meeting Abstract
Rheumatology
Holly Philpott, Trevor Birmingham, McKenzie Carter, Robert Giffin, Edward Vasarhelyi, Steven MacDonald, Brent Lanting, Tom Appleton
JOURNAL OF RHEUMATOLOGY
(2022)
Meeting Abstract
Orthopedics
H. T. Philpott, T. B. Birmingham, B. Fiset, L. A. Walsh, J. Klapak, J. Giffin, E. M. Vasarhelyi, S. J. MacDonald, B. A. Lanting, C. Appleton
OSTEOARTHRITIS AND CARTILAGE
(2022)
Article
Orthopedics
Mina W. Morcos, James L. Howard, Brent Lanting, Steven MacDonald, Douglas Naudie, Richard McCalden, Edward M. Vasarhelyi
Summary: The study found that there was no increased risk of aseptic loosening or revision surgery in patients with non-stemmed primary VVC TKA compared to those with stemmed VVC TKA at mid-term follow-up, and the non-stemmed cohort had a significantly higher final total KSS.
ORTHOPEDIC RESEARCH AND REVIEWS
(2021)