First‐in‐human clinical trial to assess the safety, tolerability and pharmacokinetics of P218, a novel candidate for malaria chemoprotection
Published 2020 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
First‐in‐human clinical trial to assess the safety, tolerability and pharmacokinetics of P218, a novel candidate for malaria chemoprotection
Authors
Keywords
-
Journal
BRITISH JOURNAL OF CLINICAL PHARMACOLOGY
Volume -, Issue -, Pages -
Publisher
Wiley
Online
2020-01-11
DOI
10.1111/bcp.14219
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Optimal dosing of dihydroartemisinin-piperaquine for seasonal malaria chemoprevention in young children
- (2019) Palang Chotsiri et al. Nature Communications
- A systematic review and meta‐analysis of dihydroartemisinin‐piperaquine versus sulphadoxine‐pyrimethamine for malaria prevention in pregnancy
- (2019) Atinuke Olaleye et al. INTERNATIONAL JOURNAL OF GYNECOLOGY & OBSTETRICS
- Safety Assessment of Acyl Glucuronides—A Simplified Paradigm
- (2018) Dennis A. Smith et al. DRUG METABOLISM AND DISPOSITION
- Experimental infection of human volunteers
- (2018) Meta Roestenberg et al. LANCET INFECTIOUS DISEASES
- New developments in anti-malarial target candidate and product profiles
- (2017) Jeremy N. Burrows et al. MALARIA JOURNAL
- Mapping sulphadoxine-pyrimethamine-resistant Plasmodium falciparum malaria in infected humans and in parasite populations in Africa
- (2017) Lucy C. Okell et al. Scientific Reports
- Impact of Sulfadoxine-Pyrimethamine Resistance on Effectiveness of Intermittent Preventive Therapy for Malaria in Pregnancy at Clearing Infections and Preventing Low Birth Weight
- (2015) Meghna Desai et al. CLINICAL INFECTIOUS DISEASES
- Lack of effect of intermittent preventive treatment for malaria in pregnancy and intense drug resistance in western Uganda
- (2015) Vera Braun et al. MALARIA JOURNAL
- First-in-Humans Study of the Safety, Tolerability, and Pharmacokinetics of ACT-451840, a New Chemical Entity with Antimalarial Activity
- (2014) Shirin Bruderer et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Origins of the specificity of inhibitor P218 toward wild-type and mutantPfDHFR: a molecular dynamics analysis
- (2014) Sheenu Abbat et al. JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS
- Folic Acid and Folinic Acid for Reducing Side Effects in Patients Receiving Methotrexate for Rheumatoid Arthritis
- (2014) B. Shea et al. JOURNAL OF RHEUMATOLOGY
- Impact of folate supplementation on the efficacy of sulfadoxine/pyrimethamine in preventing malaria in pregnancy: the potential of 5-methyl-tetrahydrofolate
- (2013) A. Nzila et al. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
- Fast in vitro methods to determine the speed of action and the stage-specificity of anti-malarials in Plasmodium falciparum
- (2013) Claire Le Manach et al. MALARIA JOURNAL
- Malarial dihydrofolate reductase as a paradigm for drug development against a resistance-compromised target
- (2012) Y. Yuthavong et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Become a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get StartedAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started