miR-27a is a master regulator of metabolic reprogramming and chemoresistance in colorectal cancer

Very low intensity ultrasounds as a new strategy to improve selective delivery of nanoparticles-complexes in cancer cells

(2019) Rossella Loria et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Cellular Plasticity in Cancer

(2019) Salina Yuan et al.   Cancer Discovery

Metabolic Symbiosis and Immunomodulation: How Tumor Cell-Derived Lactate May Disturb Innate and Adaptive Immune Responses

(2018) Alexandre Morrot et al.   Frontiers in Oncology

Lactate: A Metabolic Driver in the Tumour Landscape

(2018) Luigi Ippolito et al.   TRENDS IN BIOCHEMICAL SCIENCES

miR-194 as predictive biomarker of responsiveness to neoadjuvant chemoradiotherapy in patients with locally advanced rectal adenocarcinoma

(2017) Edoardo D’Angelo et al.   JOURNAL OF CLINICAL PATHOLOGY

AMPK: Mechanisms of Cellular Energy Sensing and Restoration of Metabolic Balance

(2017) Daniel Garcia et al.   MOLECULAR CELL

Global metabolic reprogramming of colorectal cancer occurs at adenoma stage and is induced by MYC

(2017) Kiyotoshi Satoh et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Dual Roles of MYC in Genomic Instability and Cancer Chemoresistance

(2017) Alpana Kumari et al.   Genes

Influence of microRNAs and Long Non-Coding RNAs in Cancer Chemoresistance

(2017) Duncan Ayers et al.   Genes

Growth rate inhibition metrics correct for confounders in measuring sensitivity to cancer drugs

(2016) Marc Hafner et al.   NATURE METHODS

miR-27a-mediated antiproliferative effects of metformin on the breast cancer cell line MCF-7

(2016) Wei Zhao et al.   ONCOLOGY REPORTS

Proteomic screening identifies calreticulin as a miR-27a direct target repressing MHC class I cell surface exposure in colorectal cancer

(2016) T Colangelo et al.   Cell Death & Disease

The miR-27a-calreticulin axis affects drug-induced immunogenic cell death in human colorectal cancer cells

(2016) T Colangelo et al.   Cell Death & Disease

Serum miR-125b is a non-invasive predictive biomarker of the pre-operative chemoradiotherapy responsiveness in patients with rectal adenocarcinoma

(2016) Edoardo D’Angelo et al.   Oncotarget

Fundamentals of cancer metabolism

(2016) R. J. DeBerardinis et al.   Science Advances

The emerging roles of microRNAs in cancer metabolism

(2015) Brian Chan et al.   CANCER LETTERS

Risk communication in times of crisis: Pitfalls and challenges in ensuring preparedness instead of hysterics

(2015) G.-F. Bo l   EMBO REPORTS

Targeting stromal-induced pyruvate kinase M2 nuclear translocation impairs oxphos and prostate cancer metastatic spread

(2015) Elisa Giannoni et al.   Oncotarget

5-Fluorouracil resistant colon cancer cells are addicted to OXPHOS to survive and enhance stem-like traits

(2015) Corti Denise et al.   Oncotarget

Cladosporol A, a new peroxisome proliferator-activated receptor γ (PPARγ) ligand, inhibits colorectal cancer cells proliferation through β-catenin/TCF pathway inactivation

(2014) Diana Zurlo et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

microRNAs miR-27a and miR-27b Directly Regulate Liver Dihydropyrimidine Dehydrogenase Expression through Two Conserved Binding Sites

(2014) S. M. Offer et al.   MOLECULAR CANCER THERAPEUTICS

MicroRNAs as therapeutic targets in chemoresistance

(2013) Michela Garofalo et al.   DRUG RESISTANCE UPDATES

Cross-talk between MET and EGFR in non-small cell lung cancer involves miR-27a and Sprouty2

(2013) M. Acunzo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Targeting cellular metabolism to improve cancer therapeutics

(2013) Y Zhao et al.   Cell Death & Disease

Chemoprevention, chemotherapy, and chemoresistance in colorectal cancer

(2012) Jose J. G. Marin et al.   DRUG METABOLISM REVIEWS

miR-24-3p and miR-27a-3p promote cell proliferation in glioma cells via cooperative regulation of MXI1

(2012) WEIYI XU et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

Roles of microRNA on cancer cell metabolism

(2012) Bing Chen et al.   Journal of Translational Medicine

MicroRNAs in metabolism and metabolic disorders

(2012) Veerle Rottiers et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

miR-23a Promotes the Transition from Indolent to Invasive Colorectal Cancer

(2012) Sohail Jahid et al.   Cancer Discovery

Regulation of PGC-1α, a nodal regulator of mitochondrial biogenesis

(2011) Pablo J Fernandez-Marcos et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

The AMPK signalling pathway coordinates cell growth, autophagy and metabolism

(2011) Maria M. Mihaylova et al.   NATURE CELL BIOLOGY

Hypoxia-inducible factor 1: Regulator of mitochondrial metabolism and mediator of ischemic preconditioning

(2010) Gregg L. Semenza   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

MiR-27a modulates MDR1/P-glycoprotein expression by targeting HIPK2 in human ovarian cancer cells

(2010) Zhimin Li et al.   GYNECOLOGIC ONCOLOGY

Resistance May Not Be Futile: microRNA Biomarkers for Chemoresistance and Potential Therapeutics

(2010) K. E. Allen et al.   MOLECULAR CANCER THERAPEUTICS

Origins and Mechanisms of miRNAs and siRNAs

(2009) Richard W. Carthew et al.   CELL

Akt-dependent and -independent mechanisms of mTOR regulation in cancer

(2009) Regan M. Memmott et al.   CELLULAR SIGNALLING

Tumor suppressors and cell metabolism: a recipe for cancer growth

(2009) R. G. Jones et al.   GENES & DEVELOPMENT

The Biology of Cancer: Metabolic Reprogramming Fuels Cell Growth and Proliferation

(2008) Ralph J. DeBerardinis et al.   Cell Metabolism

FBXW7 Targets mTOR for Degradation and Cooperates with PTEN in Tumor Suppression

(2008) Jian-Hua Mao et al.   SCIENCE