High-resolution imaging mass spectrometry combined with transcriptomic analysis identified a link between fatty acid composition of phosphatidylinositols and the immune checkpoint pathway at the primary tumour site of breast cancer

The asymmetry of plasma membranes and their cholesterol content influence the uptake of cisplatin

(2019) Timothée Rivel et al.   Scientific Reports

Integrated Pharmacodynamic Analysis Identifies Two Metabolic Adaption Pathways to Metformin in Breast Cancer

(2018) Simon R. Lord et al.   Cell Metabolism

Fatty acid synthase (FASN) as a therapeutic target in breast cancer

(2017) Javier A. Menendez et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Inhibition of cancer migration and invasion by knocking down delta-5-desaturase in COX-2 overexpressed cancer cells

(2017) Xiaoyu Yang et al.   Redox Biology

On-Tissue Derivatization via Electrospray Deposition for Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry Imaging of Endogenous Fatty Acids in Rat Brain Tissues

(2016) Qian Wu et al.   ANALYTICAL CHEMISTRY

Imaging of Esophageal Lymph Node Metastases by Desorption Electrospray Ionization Mass Spectrometry

(2016) Nima Abbassi-Ghadi et al.   CANCER RESEARCH

Lipid desaturation - the next step in targeting lipogenesis in cancer?

(2016) Barrie Peck et al.   FEBS Journal

Dual Roles of Group IID Phospholipase A2in Inflammation and Cancer

(2016) Yoshimi Miki et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Imaging mass spectrometry reveals loss of polyunsaturated cardiolipins in the cortical contusion, hippocampus, and thalamus after traumatic brain injury

(2016) Louis J. Sparvero et al.   JOURNAL OF NEUROCHEMISTRY

Accumulation of arachidonic acid-containing phosphatidylinositol at the outer edge of colorectal cancer

(2016) Takanori Hiraide et al.   Scientific Reports

ESI–MS/MS and MALDI-IMS Localization Reveal Alterations in Phosphatidic Acid, Diacylglycerol, and DHA in Glioma Stem Cell Xenografts

(2015) Norelle C. Wildburger et al.   JOURNAL OF PROTEOME RESEARCH

Membrane lipid therapy: Modulation of the cell membrane composition and structure as a molecular base for drug discovery and new disease treatment

(2015) Pablo V. Escribá et al.   PROGRESS IN LIPID RESEARCH

Prognostic and predictive value of PDL1 expression in breast cancer

(2015) Renaud Sabatier et al.   Oncotarget

P53 Mutations Change Phosphatidylinositol Acyl Chain Composition

(2015) Adam Naguib et al.   Cell Reports

The evaluation of tumor-infiltrating lymphocytes (TILs) in breast cancer: recommendations by an International TILs Working Group 2014

(2014) R. Salgado et al.   ANNALS OF ONCOLOGY

In Situ Tumor PD-L1 mRNA Expression Is Associated with Increased TILs and Better Outcome in Breast Carcinomas

(2014) K. A. Schalper et al.   CLINICAL CANCER RESEARCH

Fatty acid and phospholipid biosynthetic pathways are regulated throughout mammary epithelial cell differentiation and correlate to breast cancer survival

(2014) M. Luisa Dória et al.   FASEB JOURNAL

MALDI TOF imaging mass spectrometry in clinical pathology: A valuable tool for cancer diagnostics (Review)

(2014) JÖRG KRIEGSMANN et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

Full-length RNA-seq from single cells using Smart-seq2

(2014) Simone Picelli et al.   Nature Protocols

The Expression Profile of Phosphatidylinositol in High Spatial Resolution Imaging Mass Spectrometry as a Potential Biomarker for Prostate Cancer

(2014) Takayuki Goto et al.   PLoS One

Chemo-informatic strategy for imaging mass spectrometry-based hyperspectral profiling of lipid signatures in colorectal cancer

(2014) K. A. Veselkov et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Hypoxia, lipids, and cancer: surviving the harsh tumor microenvironment

(2014) Daniel Ackerman et al.   TRENDS IN CELL BIOLOGY

Differentially localized acyl-CoA synthetase 4 isoenzymes mediate the metabolic channeling of fatty acids towards phosphatidylinositol

(2013) Eva-Maria Küch et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Lipid antigens in immunity

(2013) C. Marie Dowds et al.   BIOLOGICAL CHEMISTRY

High-resolution imaging mass spectrometry reveals detailed spatial distribution of phosphatidylinositols in human breast cancer

(2013) Masahiro Kawashima et al.   CANCER SCIENCE

Polyunsaturated fatty acids affect the localization and signaling of PIP3/AKT in prostate cancer cells

(2013) Zhennan Gu et al.   CARCINOGENESIS

Human Breast Cancer Tissues Contain Abundant Phosphatidylcholine(36∶1) with High Stearoyl-CoA Desaturase-1 Expression

(2013) Yoshimi Ide et al.   PLoS One

Recognition of microbial and mammalian phospholipid antigens by NKT cells with diverse TCRs

(2013) R. V. V. Tatituri et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Depletion ofmboa-7, an enzyme that incorporates polyunsaturated fatty acids into phosphatidylinositol (PI), impairs PI 3-phosphate signaling inCaenorhabditis elegans

(2012) Hyeon-Cheol Lee et al.   GENES TO CELLS

Lipidomic analysis of phospholipids from human mammary epithelial and breast cancer cell lines

(2012) M. Luísa Dória et al.   JOURNAL OF CELLULAR PHYSIOLOGY

LPIAT1 regulates arachidonic acid content in phosphatidylinositol and is required for cortical lamination in mice

(2012) Hyeon-Cheol Lee et al.   MOLECULAR BIOLOGY OF THE CELL

Comprehensive molecular portraits of human breast tumours

(2012) Daniel C. Koboldt et al.   NATURE

The genomic and transcriptomic architecture of 2,000 breast tumours reveals novel subgroups

(2012) Christina Curtis et al.   NATURE

The cBio Cancer Genomics Portal: An Open Platform for Exploring Multidimensional Cancer Genomics Data: Figure 1.

(2012) Ethan Cerami et al.   Cancer Discovery

Real-time analysis of living animals by electrospray ionization mass spectrometry

(2011) Kentaro Yoshimura et al.   ANALYTICAL BIOCHEMISTRY

Novel Theranostic Opportunities Offered by Characterization of Altered Membrane Lipid Metabolism in Breast Cancer Progression

(2011) M. Hilvo et al.   CANCER RESEARCH

American Society of Clinical Oncology/College of American Pathologists Guideline Recommendations for Immunohistochemical Testing of Estrogen and Progesterone Receptors in Breast Cancer

(2010) M. Elizabeth H. Hammond et al.   JOURNAL OF CLINICAL ONCOLOGY

Intracellular Phospholipase A1 and Acyltransferase, Which Are Involved in Caenorhabditis elegans Stem Cell Divisions, Determine the sn-1 Fatty Acyl Chain of Phosphatidylinositol

(2010) Rieko Imae et al.   MOLECULAR BIOLOGY OF THE CELL

Visualization of Volatile Substances in Different Organelles with an Atmospheric-Pressure Mass Microscope

(2009) Takahiro Harada et al.   ANALYTICAL CHEMISTRY

Metformin and Pathologic Complete Responses to Neoadjuvant Chemotherapy in Diabetic Patients With Breast Cancer

(2009) Sao Jiralerspong et al.   JOURNAL OF CLINICAL ONCOLOGY

Visualization of the cell-selective distribution of PUFA-containing phosphatidylcholines in mouse brain by imaging mass spectrometry

(2009) Yuki Sugiura et al.   JOURNAL OF LIPID RESEARCH

Fatty Acid Synthase Gene Is Up-regulated by Hypoxia via Activation of Akt and Sterol Regulatory Element Binding Protein-1

(2008) E. Furuta et al.   CANCER RESEARCH

Fatty acid-binding proteins: role in metabolic diseases and potential as drug targets

(2008) Masato Furuhashi et al.   NATURE REVIEWS DRUG DISCOVERY

Membrane lipids: where they are and how they behave

(2008) Gerrit van Meer et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY