Intervertebral disc degeneration in mice with type II diabetes induced by leptin receptor deficiency

Vitamin D improves the content of TGF-β and IGF-1 in intervertebral disc of diabetic rats

(2017) Ji-long An et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Advanced glycation end products regulate anabolic and catabolic activities via NLRP3-inflammasome activation in human nucleus pulposus cells

(2017) Yu Song et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Does clinical improvement of symptomatic degenerative lumbar disease impact obesity?

(2017) Jacob R. Joseph et al.   JOURNAL OF NEUROSURGERY-SPINE

Molecular profile of major growth factors in lumbar intervertebral disc herniation: Correlation with patient clinical and epidemiological characteristics

(2017) Alexandros Tsarouhas et al.   Molecular Medicine Reports

Associations between Obesity and Spinal Diseases: A Medical Expenditure Panel Study Analysis

(2017) Binwu Sheng et al.   International Journal of Environmental Research and Public Health

Prevalence of Modic changes in the lumbar vertebrae and their associations with workload, smoking and weight in northern China

(2017) Chao Han et al.   Scientific Reports

Possible involvement of the oxLDL/LOX-1 system in the pathogenesis and progression of human intervertebral disc degeneration or herniation

(2017) Xinhua Li et al.   Scientific Reports

Insulin-like growth factor-1 deficiency and metabolic syndrome

(2016) G. A. Aguirre et al.   Journal of Translational Medicine

Diabetes-accelerated experimental osteoarthritis is prevented by autophagy activation

(2016) M. Ribeiro et al.   OSTEOARTHRITIS AND CARTILAGE

Percutaneous endoscopic lumbar discectomy for recurrent lumbar disc herniation

(2016) Xinhua Li et al.   International Journal of Surgery

Suppressing hyperinsulinemia prevents obesity but causes rapid onset of diabetes in leptin-deficient Lep ob/ob mice

(2016) Anna M. D'souza et al.   Molecular Metabolism

Validity of leptin receptor-deficiency (db/db) type 2 diabetes mellitus mice as a model of secondary osteoporosis

(2016) Le Huang et al.   Scientific Reports

Overexpression of insulin receptor partially improves obese and diabetic phenotypes in db/db mice

(2015) Tsutomu Sasaki et al.   ENDOCRINE JOURNAL

Chronic Ingestion of Advanced Glycation End Products Induces Degenerative Spinal Changes and Hypertrophy in Aging Pre-Diabetic Mice

(2015) Svenja Illien-Jünger et al.   PLoS One

ZiBuPiYin Recipe Protects db/db Mice from Diabetes-Associated Cognitive Decline through Improving Multiple Pathological Changes

(2014) Jing Chen et al.   PLoS One

Differential Gene Expression in Anterior and Posterior Annulus Fibrosus

(2014) John D. Koerner et al.   SPINE

Combined Anti-Inflammatory and Anti-AGE Drug Treatments Have a Protective Effect on Intervertebral Discs in Mice with Diabetes

(2013) Svenja Illien-Junger et al.   PLoS One

Nucleus pulposus degeneration alters properties of resident progenitor cells

(2013) Olga Mizrahi et al.   Spine Journal

Diabetic db/db mice exhibit central nervous system and peripheral molecular alterations as seen in neurological disorders

(2013) A Ernst et al.   Translational Psychiatry

Skeletal phenotype of the leptin receptor-deficient db/db mouse

(2011) Garry A Williams et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Interleukin-1β induces angiogenesis and innervation in human intervertebral disc degeneration

(2010) Jae Man Lee et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

Extreme obesity due to impaired leptin signaling in mice does not cause knee osteoarthritis

(2009) Timothy M. Griffin et al.   ARTHRITIS AND RHEUMATISM

Association of a Single Nucleotide Polymorphism in the Insulin-Like Growth Factor-1 Receptor Gene With Spinal Disc Degeneration in Postmenopausal Japanese Women

(2009) Tomohiko Urano et al.   SPINE

Expression of Leptin and Its Functional Receptor on Disc Cells

(2008) Chang-Qing Zhao et al.   SPINE