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Abstract LB-284: Engineering a hypermutant mouse model of NSCLC to modulate immune response

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UV-induced somatic mutations elicit a functional T cell response in the YUMMER1.7 mouse melanoma model

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PD-L1 (B7-H1) and PD-1 pathway blockade for cancer therapy: Mechanisms, response biomarkers, and combinations

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pVAC-Seq: A genome-guided in silico approach to identifying tumor neoantigens

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Rational Selection of Syngeneic Preclinical Tumor Models for Immunotherapeutic Drug Discovery

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Molecular and Genetic Properties of Tumors Associated with Local Immune Cytolytic Activity

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Immune Checkpoint Targeting in Cancer Therapy: Toward Combination Strategies with Curative Potential

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Epigenetic silencing of TH1-type chemokines shapes tumour immunity and immunotherapy

(2015) Dongjun Peng et al.   NATURE

Melanoma-intrinsic β-catenin signalling prevents anti-tumour immunity

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The prognostic landscape of genes and infiltrating immune cells across human cancers

(2015) Andrew J Gentles et al.   NATURE MEDICINE

High-throughput screening using patient-derived tumor xenografts to predict clinical trial drug response

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Translational value of mouse models in oncology drug development

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Mutational landscape determines sensitivity to PD-1 blockade in non-small cell lung cancer

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Immunomic, genomic and transcriptomic characterization of CT26 colorectal carcinoma

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CTLA-4 Is Expressed by Activated Mouse NK Cells and Inhibits NK Cell IFN-  Production in Response to Mature Dendritic Cells

(2014) A. Stojanovic et al.   JOURNAL OF IMMUNOLOGY

Accurate Proteome-wide Label-free Quantification by Delayed Normalization and Maximal Peptide Ratio Extraction, Termed MaxLFQ

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Genetic Basis for Clinical Response to CTLA-4 Blockade in Melanoma

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Mutated tumor alleles are expressed according to their DNA frequency

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Immunogenicity of Murine Solid Tumor Models as a Defining Feature of In Vivo Behavior and Response to Immunotherapy

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Signatures of mutational processes in human cancer

(2013) Ludmil B. Alexandrov et al.   NATURE

A program for annotating and predicting the effects of single nucleotide polymorphisms, SnpEff

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VarScan 2: Somatic mutation and copy number alteration discovery in cancer by exome sequencing

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The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity

(2012) Jordi Barretina et al.   NATURE

Fast gapped-read alignment with Bowtie 2

(2012) Ben Langmead et al.   NATURE METHODS

Molecular Genetics of Colorectal Cancer

(2011) Eric R. Fearon   Annual Review of Pathology-Mechanisms of Disease

SomaticSniper: identification of somatic point mutations in whole genome sequencing data

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RSEM: accurate transcript quantification from RNA-Seq data with or without a reference genome

(2011) Bo Li et al.   BMC BIOINFORMATICS

Andromeda: A Peptide Search Engine Integrated into the MaxQuant Environment

(2011) Jürgen Cox et al.   JOURNAL OF PROTEOME RESEARCH

Fast and accurate short read alignment with Burrows-Wheeler transform

(2009) H. Li et al.   BIOINFORMATICS

MaxQuant enables high peptide identification rates, individualized p.p.b.-range mass accuracies and proteome-wide protein quantification

(2008) Jürgen Cox et al.   NATURE BIOTECHNOLOGY