Understanding the effect of high gas entrance velocity on Chinese hamster ovary (CHO) cell culture performance and its implications on bioreactor scale‐up and sparger design

Shear contributions to cell culture performance and product recovery in ATF and TFF perfusion systems

(2017) Samantha Wang et al.   JOURNAL OF BIOTECHNOLOGY

Mixing, aeration and cell damage, 30+ years later: what we learned, how it affected the cell culture industry and what we would like to know more about

(2015) Jeffrey J Chalmers   Current Opinion in Chemical Engineering

Application of bioreactor design principles and multivariate analysis for development of cell culture scale down models

(2014) Lia Tescione et al.   BIOTECHNOLOGY AND BIOENGINEERING

Effects of bubble-liquid two-phase turbulent hydrodynamics on cell damage in sparged bioreactor

(2013) Yang Liu et al.   BIOTECHNOLOGY PROGRESS

Development of a scaled-down aerobic fermentation model for scale-up in recombinant protein vaccine manufacturing

(2012) Patrick Farrell et al.   VACCINE

The potential of hydrodynamic damage to animal cells of industrial relevance: current understanding

(2011) Weiwei Hu et al.   CYTOTECHNOLOGY

Cell death in mammalian cell culture: molecular mechanisms and cell line engineering strategies

(2010) Britta Krampe et al.   CYTOTECHNOLOGY

Induction of mammalian cell death by simple shear and extensional flows

(2009) Timm Tanzeglock et al.   BIOTECHNOLOGY AND BIOENGINEERING

NS0 cell damage by high gas velocity sparging in protein-free and cholesterol-free cultures

(2008) Ying Zhu et al.   BIOTECHNOLOGY AND BIOENGINEERING