4.5 Article

Post-traumatic stress disorder associated with life-threatening motor vehicle collisions in the WHO World Mental Health Surveys

Journal

BMC PSYCHIATRY
Volume 16, Issue -, Pages -

Publisher

BMC
DOI: 10.1186/s12888-016-0957-8

Keywords

Posttraumatic stress disorder; PTSD; Motor vehicle collision

Categories

Funding

  1. National Institute of Mental Health (NIMH) [R01 MH070884, U01-MH60220]
  2. John D. and Catherine T. MacArthur Foundation
  3. Pfizer Foundation
  4. US Public Health Service [R13-MH066849, R01-MH069864, R01 DA016558]
  5. Fogarty International Center [FIRCA R03-TW006481]
  6. Pan American Health Organization
  7. Eli Lilly and Company
  8. Ortho-McNeil Pharmaceutical
  9. GlaxoSmithKline
  10. Bristol-Myers Squibb
  11. Ministry of Health
  12. National Center for Public Health Protection
  13. Ministry of Social Protection
  14. Center for Excellence on Research in Mental Health (CES University)
  15. Secretary of Health of Medellin
  16. European Commission [QLG5-1999-01042, SANCO 2004123, EAHC 20081308]
  17. Piedmont Region (Italy)
  18. Fondo de Investigacion Sanitaria, Instituto de Salud Carlos III, Spain [FIS 00/0028]
  19. Ministerio de Ciencia y Tecnologia, Spain [SAF 2000-158-CE]
  20. Departament de Salut, Generalitat de Catalunya, Spain
  21. Instituto de Salud Carlos III [CIBER CB06/02/0046, RETICS RD06/0011 REM-TAP]
  22. Israel National Institute for Health Policy and Health Services Research
  23. National Insurance Institute of Israel
  24. Lebanese Ministry of Public Health
  25. WHO (Lebanon)
  26. National Institute of Health/Fogarty International Center [R03 TW006481-01]
  27. Sheikh Hamdan Bin Rashid Al Maktoum Award for Medical Sciences
  28. AstraZeneca
  29. Eli Lilly
  30. Hikma Pharmaceuticals
  31. Janssen Cilag
  32. Lundbeck
  33. Novartis
  34. Servier
  35. National Institute of Psychiatry Ramon de la Fuente [INPRFMDIES 4280]
  36. National Council on Science and Technology [CONACyT-G30544-H]
  37. National Institute of Health of the Ministry of Health of Peru
  38. Regional Health Authority of Murcia (Consejeria de Sanidad y Politica Social)
  39. Fundacion para la Formacion e Investigacion Sanitarias (FFIS) of Murcia
  40. US National Institute of Mental Health [R01-MH059575, RO1-MH61905]
  41. National Institute of Drug Abuse
  42. South African Department of Health
  43. University of Michigan
  44. South African Medical Research Council
  45. Robert Wood Johnson Foundation (RWJF) [044708]
  46. Regional Health Authority of Murcia (Servicio Murciano de Salud)

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Background: Motor vehicle collisions (MVCs) are a substantial contributor to the global burden of disease and lead to subsequent post-traumatic stress disorder (PTSD). However, the relevant literature originates in only a few countries, and much remains unknown about MVC-related PTSD prevalence and predictors. Methods: Data come from the World Mental Health Survey Initiative, a coordinated series of community epidemiological surveys of mental disorders throughout the world. The subset of 13 surveys (5 in high income countries, 8 in middle or low income countries) with respondents reporting PTSD after life-threatening MVCs are considered here. Six classes of predictors were assessed: socio-demographics, characteristics of the MVC, childhood family adversities, MVCs, other traumatic experiences, and respondent history of prior mental disorders. Logistic regression was used to examine predictors of PTSD. Mental disorders were assessed with the fully-structured Composite International Diagnostic Interview using DSM-IV criteria. Results: Prevalence of PTSD associated with MVCs perceived to be life-threatening was 2.5 % overall and did not vary significantly across countries. PTSD was significantly associated with low respondent education, someone dying in the MVC, the respondent or someone else being seriously injured, childhood family adversities, prior MVCs (but not other traumatic experiences), and number of prior anxiety disorders. The final model was significantly predictive of PTSD, with 32 % of all PTSD occurring among the 5 % of respondents classified by the model as having highest PTSD risk. Conclusion: Although PTSD is a relatively rare outcome of life-threatening MVCs, a substantial minority of PTSD cases occur among the relatively small proportion of people with highest predicted risk. This raises the question whether MVC-related PTSD could be reduced with preventive interventions targeted to high-risk survivors using models based on predictors assessed in the immediate aftermath of the MVCs.

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