The congenital cataract‐causing mutations P20R and A171T are associated with important changes in the amyloidogenic feature, structure and chaperone‐like activity of human αB‐crystallin

Characterization of an N-terminal mutant of αA-crystallin αA–R21Q associated with congenital cataract

(2018) Ashutosh S. Phadte et al.   EXPERIMENTAL EYE RESEARCH

Therapeutic potential of α-crystallin

(2016) Ram H. Nagaraj et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Evaluation of structure, chaperone-like activity and protective ability of peroxynitrite modified human α-Crystallin subunits against copper-mediated ascorbic acid oxidation

(2016) Maryam Ghahramani et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

On the purported “backbone fluorescence” in protein three-dimensional fluorescence spectra

(2016) Annalisa Bortolotti et al.   RSC Advances

Concomitant Raman spectroscopy and dynamic light scattering for characterization of therapeutic proteins at high concentrations

(2015) Chen Zhou et al.   ANALYTICAL BIOCHEMISTRY

A Mechanism of Subunit Recruitment in Human Small Heat Shock Protein Oligomers

(2015) Scott P. Delbecq et al.   BIOCHEMISTRY

Missense Mutations in CRYAB Are Liable for Recessive Congenital Cataracts

(2015) Xiaodong Jiaox et al.   PLoS One

Binding interactions of niclosamide with serum proteins

(2014) Esra Maltas   JOURNAL OF FOOD AND DRUG ANALYSIS

The structured core domain of  B-crystallin can prevent amyloid fibrillation and associated toxicity

(2014) G. K. A. Hochberg et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dynamical structure of αB-crystallin

(2014) Georg K.A. Hochberg et al.   PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY

A novel P20R mutation in the alpha-B crystallin gene causes autosomal dominant congenital posterior polar cataracts in a Chinese family

(2014) Xin-Yi Xia et al.   BMC Ophthalmology

Raman spectroscopy of proteins: a review

(2013) A. Rygula et al.   JOURNAL OF RAMAN SPECTROSCOPY

Regulated structural transitions unleash the chaperone activity of  B-crystallin

(2013) J. Peschek et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A P39R mutation at the N-terminal domain of human αB-crystallin regulates its oligomeric state and chaperone-like activity

(2012) Nobutaka Numoto et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Mutants of human αB-crystallin cause enhanced protein aggregation and apoptosis in mammalian cells: Influence of co-expression of HspB1

(2012) Ilangovan Raju et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

sHSP in the eye lens: Crystallin mutations, cataract and proteostasis

(2012) Alice R. Clark et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

N-terminal domain of  B-crystallin provides a conformational switch for multimerization and structural heterogeneity

(2011) S. Jehle et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Independent evolution of the core domain and its flanking sequences in small heat shock proteins

(2010) Thomas Kriehuber et al.   FASEB JOURNAL

Importance of eye lens α-crystallin heteropolymer with 3:1 αA to αB ratio: Stability, aggregation, and modifications

(2010) Pasumarthi Srinivas et al.   IUBMB LIFE

Detection and Architecture of Small Heat Shock Protein Monomers

(2010) Pierre Poulain et al.   PLoS One

Crystal structures of truncated alphaA and alphaB crystallins reveal structural mechanisms of polydispersity important for eye lens function

(2010) Arthur Laganowsky et al.   PROTEIN SCIENCE

Lens aging: Effects of crystallins

(2009) K. Krishna Sharma et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Crystal Structures of α-Crystallin Domain Dimers of αB-Crystallin and Hsp20

(2009) C. Bagnéris et al.   JOURNAL OF MOLECULAR BIOLOGY

The eye lens chaperone  -crystallin forms defined globular assemblies

(2009) J. Peschek et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Abnormal Assemblies and Subunit Exchange of αB-Crystallin R120 Mutants Could Be Associated with Destabilization of the Dimeric Substructure†

(2008) Magalie Michiel et al.   BIOCHEMISTRY

Cataract mutation P20S of αB-crystallin impairs chaperone activity of αA-crystallin and induces apoptosis of human lens epithelial cells

(2008) Hui Li et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Genetics of crystallins: Cataract and beyond

(2008) Jochen Graw   EXPERIMENTAL EYE RESEARCH

Selective Cu2+ Binding, Redox Silencing, and Cytoprotective Effects of the Small Heat Shock Proteins αA- and αB-Crystallin

(2008) Md. Faiz Ahmad et al.   JOURNAL OF MOLECULAR BIOLOGY

Extrinsic Fluorescent Dyes as Tools for Protein Characterization

(2008) Andrea Hawe et al.   PHARMACEUTICAL RESEARCH

Congenital cataracts and their molecular genetics

(2007) J. Fielding Hejtmancik   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY