Journal
BIOMEDICINE & PHARMACOTHERAPY
Volume 123, Issue -, Pages -Publisher
ELSEVIER FRANCE-EDITIONS SCIENTIFIQUES MEDICALES ELSEVIER
DOI: 10.1016/j.biopha.2019.109799
Keywords
MicroRNA-613; Cancer; Target gene; Target therapy
Funding
- Youth Medicine Project of Jiangsu Province [QNRC2016166]
- Wuxi Science and Technology Bureau Project [CSE31N1720]
- Jiangsu Provincial Six Talent Peaks Project [YY-124]
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MicroRNAs (miRNAs) are short-chain non-coding RNAs that act as critical roles in malignant tumorigenesis via regulating the expression of tumor-associated genes through post-transcriptional level based on specific binding to their target genes. MicroRNA-613 (miR-613) is a new-found miRNA and emerging evidences show that miR-613 participates in multiple physiological and pathological processes. Recent studies have exhibited that miR-613 is abnormally expressed in a variety of cancers and act as important roles in the progression of cancers. To be specific, miR-613 is generally identified as a tumor suppressor in multiple cancers. In this review, we systematically summarize the roles of miR-613 and highlight the potential correlation between miR-613 expression and clinical features in human cancers.
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