EJP18 peptide derived from the juxtamembrane domain of epidermal growth factor receptor represents a novel membrane-active cell-penetrating peptide

Recent Advances in Cell Penetrating Peptide-Based Anticancer Therapies

(2019) Justine Habault et al.   MOLECULES

Cell-penetrating peptide sequence and modification dependent uptake and subcellular distribution of green florescent protein in different cell lines

(2019) Sanjay G. Patel et al.   Scientific Reports

Stereochemistry as a determining factor for the effect of a cell-penetrating peptide on cellular viability and epithelial integrity

(2018) Ditlev Birch et al.   BIOCHEMICAL JOURNAL

Contrasting roles for actin in the cellular uptake of cell penetrating peptide conjugates

(2018) L. He et al.   Scientific Reports

Targeting EGFR/HER2/HER3 with a Three-in-One Aptamer-siRNA Chimera Confers Superior Activity against HER2 + Breast Cancer

(2018) Xiaolin Yu et al.   Molecular Therapy-Nucleic Acids

Oligomer Formation Propensities of Dimeric Bundle Peptides Correlate with Cell Penetration Abilities

(2018) Soonsil Hyun et al.   ACS Central Science

Inhibiting Epidermal Growth Factor Receptor Dimerization and Signaling Through Targeted Delivery of a Juxtamembrane Domain Peptide Mimic

(2018) Janessa Gerhart et al.   ACS Chemical Biology

Cell penetrating peptides in preclinical and clinical cancer diagnosis and therapy

(2018) Prem Prakash Tripathi et al.   Oncotarget

A Ragulator–BORC interaction controls lysosome positioning in response to amino acid availability

(2017) Jing Pu et al.   JOURNAL OF CELL BIOLOGY

Emerging functions of the EGFR in cancer

(2017) Sara Sigismund et al.   Molecular Oncology

The lure of the lipids: how defensins exploit membrane phospholipids to induce cytolysis in target cells

(2017) Amy A Baxter et al.   Cell Death & Disease

Role of autophagy in cell-penetrating peptide transfection model

(2017) Moataz Dowaidar et al.   Scientific Reports

Identification of Short Hydrophobic Cell-Penetrating Peptides for Cytosolic Peptide Delivery by Rational Design

(2016) Samuel Schmidt et al.   BIOCONJUGATE CHEMISTRY

PtdIns(4,5)P2signaling regulates ATG14 and autophagy

(2016) Xiaojun Tan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Quantification of Epidermal Growth Factor Receptor Expression Level and Binding Kinetics on Cell Surfaces by Surface Plasmon Resonance Imaging

(2015) Fenni Zhang et al.   ANALYTICAL CHEMISTRY

Site of fluorescent label modifies interaction of melittin with live cells and model membranes

(2015) Elaheh Jamasbi et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

The juxtamembrane regions of human receptor tyrosine kinases exhibit conserved interaction sites with anionic lipids

(2015) George Hedger et al.   Scientific Reports

Three Valuable Peptides from Bee and Wasp Venoms for Therapeutic and Biotechnological Use: Melittin, Apamin and Mastoparan

(2015) Miguel Moreno et al.   Toxins

Cell-Penetrating Peptides: Design, Synthesis, and Applications

(2014) Dana Maria Copolovici et al.   ACS Nano

Inhibition of triple-negative and Herceptin-resistant breast cancer cell proliferation and migration by Annexin A2 antibodies

(2014) P Chaudhary et al.   BRITISH JOURNAL OF CANCER

Distal phenylalanine modification for enhancing cellular delivery of fluorophores, proteins and quantum dots by cell penetrating peptides

(2014) E.J. Sayers et al.   JOURNAL OF CONTROLLED RELEASE

Chirality Switching within an Anionic Cell-Penetrating Peptide Inhibits Translocation without Affecting Preferential Entry

(2014) Tohru Yamada et al.   MOLECULAR PHARMACEUTICS

CPP-mediated Protein Delivery in a Noncovalent Form: Proof-of-Concept for Percutaneous and Intranasal Delivery

(2014) Zhao Wang et al.   PROTEIN AND PEPTIDE LETTERS

Phosphoinositide-mediated oligomerization of a defensin induces cell lysis

(2014) Ivan KH Poon et al.   eLife

Epidermal growth factor receptor targeting in cancer: A review of trends and strategies

(2013) Chetan Yewale et al.   BIOMATERIALS

Bioportides: Bioactive cell-penetrating peptides that modulate cellular dynamics

(2013) Monika Lukanowska et al.   Biotechnology Journal

Cell penetrating peptides fail to induce an innate immune response in epithelial cells in vitro: Implications for continued therapeutic use

(2013) Edward Carter et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Cell-penetrating peptides: classes, origin, and current landscape

(2012) Francesca Milletti   DRUG DISCOVERY TODAY

Cell entry of cell penetrating peptides: tales of tails wagging dogs

(2012) Arwyn T. Jones et al.   JOURNAL OF CONTROLLED RELEASE

Fiji: an open-source platform for biological-image analysis

(2012) Johannes Schindelin et al.   NATURE METHODS

A Potential Peptide Therapeutic Derived from the Juxtamembrane Domain of the Epidermal Growth Factor Receptor

(2012) Aislyn D. W. Boran et al.   PLoS One

Design, Synthesis and Characterization of a New Anionic Cell-Penetrating Peptide: SAP(E)

(2011) Irene Martín et al.   CHEMBIOCHEM

Antimicrobial peptides with cell-penetrating peptide properties and vice versa

(2011) Katrin Splith et al.   EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS

Transduction of peptides and proteins into live cells by cell penetrating peptides

(2011) Franziska Mussbach et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

New Insight into the Mechanism of Action of Wasp Mastoparan Peptides: Lytic Activity and Clustering Observed with Giant Vesicles

(2011) Marcia P. dos Santos Cabrera et al.   LANGMUIR

Co-operative Membrane Disruption Between Cell-penetrating Peptide and Cargo: Implications for the Therapeutic Use of the Bcl-2 Converter Peptide D-NuBCP-9-r8

(2011) Catherine L Watkins et al.   MOLECULAR THERAPY

Endo-Lysosomal Vesicles Positive for Rab7 and LAMP1 Are Terminal Vesicles for the Transport of Dextran

(2011) William H. Humphries et al.   PLoS One

Cell Signaling by Receptor Tyrosine Kinases

(2010) Mark A. Lemmon et al.   CELL

Nuclear EGFR shuttling induced by ionizing radiation is regulated by phosphorylation at residue Thr654

(2010) Klaus Dittmann et al.   FEBS LETTERS

Low concentration thresholds of plasma membranes for rapid energy-independent translocation of a cell-penetrating peptide

(2009) Catherine L. Watkins et al.   BIOCHEMICAL JOURNAL

The Juxtamembrane Region of EGFR Takes Center Stage

(2009) Stevan R. Hubbard   CELL

Mechanism for Activation of the EGF Receptor Catalytic Domain by the Juxtamembrane Segment

(2009) Natalia Jura et al.   CELL

Cellular uptake, distribution and cytotoxicity of the hydrophobic cell penetrating peptide sequence PFVYLI linked to the proapoptotic domain peptide PAD

(2009) Catherine L. Watkins et al.   JOURNAL OF CONTROLLED RELEASE

Enhanced intracellular delivery using arginine-rich peptides by the addition of penetration accelerating sequences (Pas)

(2009) Kentaro Takayama et al.   JOURNAL OF CONTROLLED RELEASE

The cell-penetrating peptide octa-arginine is a potent inhibitor of proteasome activities

(2008) Alexander Kloß et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

On the Mechanism of Pore Formation by Melittin

(2008) Geert van den Bogaart et al.   JOURNAL OF BIOLOGICAL CHEMISTRY