Retinoids Repress Human Cardiovascular Cell Calcification With Evidence for Distinct Selective Retinoid Modulator Effects

Retinoic acid disrupts osteogenesis in pre-osteoblasts by down-regulating WNT signaling

(2019) Laury A. Roa et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Matrix Gla protein negatively regulates calcification of human aortic valve interstitial cells isolated from calcified aortic valves

(2018) Mari Chiyoya et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES

Cardiovascular calcification: artificial intelligence and big data accelerate mechanistic discovery

(2018) Maximillian A. Rogers et al.   Nature Reviews Cardiology

Association of Matrix Gla protein gene (rs1800801, rs1800802, rs4236) polymorphism with vascular calcification and atherosclerotic disease: a meta-analysis

(2017) Kaixiang Sheng et al.   Scientific Reports

Effects of K-877, a novel selective PPARα modulator (SPPARMα), in dyslipidaemic patients: A randomized, double blind, active- and placebo-controlled, phase 2 trial

(2016) Shun Ishibashi et al.   ATHEROSCLEROSIS

Sortilin mediates vascular calcification via its recruitment into extracellular vesicles

(2016) Claudia Goettsch et al.   JOURNAL OF CLINICAL INVESTIGATION

Peretinoin as an adjuvant therapy for hepatocellular carcinoma

(2016) Chee-Kiat Tan   Expert Review of Gastroenterology & Hepatology

Plasma Apolipoprotein C-III Levels, Triglycerides, and Coronary Artery Calcification in Type 2 DiabeticsSignificance

(2015) Arman Qamar et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Autotaxin Derived From Lipoprotein(a) and Valve Interstitial Cells Promotes Inflammation and Mineralization of the Aortic ValveCLINICAL PERSPECTIVE

(2015) Rihab Bouchareb et al.   CIRCULATION

Transcriptional Factors Mediating Retinoic Acid Signals in the Control of Energy Metabolism

(2015) Rui Zhang et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Inflammatory, Metabolic, and Genetic Mechanisms of Vascular Calcification

(2014) Linda L. Demer et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Retinaldehyde dehydrogenase 1 deficiency inhibits PPARγ-mediated bone loss and marrow adiposity

(2014) Shriram Nallamshetty et al.   BONE

Loss-of-Function Mutations in APOC3, Triglycerides, and Coronary Disease

(2014)   NEW ENGLAND JOURNAL OF MEDICINE

Vitamin A Supplementation Reduces IL-17 and RORc Gene Expression in Atherosclerotic Patients

(2014) A. Mottaghi et al.   SCANDINAVIAN JOURNAL OF IMMUNOLOGY

Deficiency of Retinaldehyde Dehydrogenase 1 Induces BMP2 and Increases Bone Mass In Vivo

(2013) Shriram Nallamshetty et al.   PLoS One

Vitamin A Is a Negative Regulator of Osteoblast Mineralization

(2013) Thomas Lind et al.   PLoS One

Revised microcalcification hypothesis for fibrous cap rupture in human coronary arteries

(2013) A. Kelly-Arnold et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A mechanistic analysis of the role of microcalcifications in atherosclerotic plaque stability: potential implications for plaque rupture

(2012) Natalia Maldonado et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Increased Dietary Intake of Vitamin A Promotes Aortic Valve Calcification In Vivo

(2012) Danielle J. Huk et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Sources of cells that contribute to atherosclerotic intimal calcification: an in vivo genetic fate mapping study

(2012) Veena Naik et al.   CARDIOVASCULAR RESEARCH

Smooth Muscle Cell–Specific Runx2 Deficiency Inhibits Vascular Calcification

(2012) Yong Sun et al.   CIRCULATION RESEARCH

Retinoic Acid Upregulates Preadipocyte Genes to Block Adipogenesis and Suppress Diet-Induced Obesity

(2012) Daniel C. Berry et al.   DIABETES

Retinoic Acid Receptor α Mediates All-trans-retinoic Acid-inducedKlf4Gene Expression by RegulatingKlf4Promoter Activity in Vascular Smooth Muscle Cells

(2012) Jian-hong Shi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Osteoporosis—a risk factor for cardiovascular disease?

(2012) Christos E. Lampropoulos et al.   Nature Reviews Rheumatology

Retinoid metabolism and its effects on the vasculature

(2011) Eun-Jung Rhee et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Reduced Sox9 Function Promotes Heart Valve Calcification Phenotypes In Vivo

(2010) Jacqueline D. Peacock et al.   CIRCULATION RESEARCH

SOX9 is a major negative regulator of cartilage vascularization, bone marrow formation and endochondral ossification

(2010) T. Hattori et al.   DEVELOPMENT

miR-10a Contributes to Retinoid Acid-induced Smooth Muscle Cell Differentiation

(2010) Huarong Huang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

SOX9 determines RUNX2 transactivity by directing intracellular degradation

(2010) Aixin Cheng et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Retinoic acid represses CYP7A1 expression in human hepatocytes and HepG2 cells by FXR/RXR-dependent and independent mechanisms

(2010) Shi-Ying Cai et al.   JOURNAL OF LIPID RESEARCH

Smooth Muscle Cells Give Rise to Osteochondrogenic Precursors and Chondrocytes in Calcifying Arteries

(2009) Mei Y. Speer et al.   CIRCULATION RESEARCH

Lower bone mineral density is associated with higher coronary calcification and coronary plaque burdens by multidetector row coronary computed tomography in pre- and postmenopausal women

(2009) Sung Hee Choi et al.   CLINICAL ENDOCRINOLOGY

Association of Coronary Artery and Aortic Calcium With Lumbar Bone Density: The MESA Abdominal Aortic Calcium Study

(2008) J. A. Hyder et al.   AMERICAN JOURNAL OF EPIDEMIOLOGY

Mineral Surface in Calcified Plaque Is Like That of Bone

(2008) Melinda J. Duer et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Retinoic acid inhibits osteogenic differentiation of rat bone marrow stromal cells

(2008) Anxun Wang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

9-Cis Retinoic Acid Reduces 1α,25-Dihydroxycholecalciferol-Induced Renal Calcification by Altering Vitamin K-Dependent γ-Carboxylation of Matrix γ-Carboxyglutamic Acid Protein in A/J Male Mice

(2008) Xueyan Fu et al.   JOURNAL OF NUTRITION