Evaluation of a multi-arm multi-stage Bayesian design for phase II drug selection trials – an example in hemato-oncology

Multistage adaptive biomarker-directed targeted design for randomized clinical trials

(2015) Zhong Gao et al.   Contemporary Clinical Trials

Simulation study for evaluating the performance of response-adaptive randomization

(2015) Yining Du et al.   Contemporary Clinical Trials

Bayesian sample sizes for exploratory clinical trials comparing multiple experimental treatments with a control

(2015) John Whitehead et al.   STATISTICS IN MEDICINE

Adaptive choice of patient subgroup for comparing two treatments

(2014) Tze Leung Lai et al.   Contemporary Clinical Trials

A comparison of Bayesian adaptive randomization and multi-stage designs for multi-arm clinical trials

(2014) James M. S. Wason et al.   STATISTICS IN MEDICINE

Rethinking Randomized Clinical Trials for Comparative Effectiveness Research: The Need for Transformational Change

(2013) Bryan R. Luce   ANNALS OF INTERNAL MEDICINE

A multi-arm multi-stage clinical trial design for binary outcomes with application to tuberculosis

(2013) Daniel J Bratton et al.   BMC Medical Research Methodology

Reporting of analyses from randomized controlled trials with multiple arms: a systematic review

(2013) Gabriel Baron et al.   BMC Medicine

Bayesian adaptive phase II screening design for combination trials

(2013) Chunyan Cai et al.   Clinical Trials

Modeling of experts’ divergent prior beliefs for a sequential phase III clinical trial

(2013) Marion Moatti et al.   Clinical Trials

A phase I/II seamless dose escalation/expansion with adaptive randomization scheme (SEARS)

(2013) Haitao Pan et al.   Clinical Trials

Bayesian two-step Lasso strategy for biomarker selection in personalized medicine development for time-to-event endpoints

(2013) Xuemin Gu et al.   Contemporary Clinical Trials

Bayesian adaptive trial design in acute heart failure syndromes: Moving beyond the mega trial

(2012) Sean P. Collins et al.   AMERICAN HEART JOURNAL

A Bayesian adaptive design for multi-dose, randomized, placebo-controlled phase I/II trials

(2012) Fang Xie et al.   Contemporary Clinical Trials

A Bayesian Inference ofP(π1 > π2) for Two Proportions

(2012) Youhei Kawasaki et al.   Journal of Biopharmaceutical Statistics

Design Issues in Randomized Phase II/III Trials

(2012) Edward L. Korn et al.   JOURNAL OF CLINICAL ONCOLOGY

Bayesian clinical trials in action

(2012) J. Jack Lee et al.   STATISTICS IN MEDICINE

Optimal design of multi-arm multi-stage trials

(2012) James M. S. Wason et al.   STATISTICS IN MEDICINE

Bayesian adaptive clinical trials: a dream for statisticians only?

(2011) Sylvie Chevret   STATISTICS IN MEDICINE

Designs for clinical trials with time-to-event outcomes based on stopping guidelines for lack of benefit

(2011) Patrick Royston et al.   Trials

Bayesian adaptive randomization designs for targeted agent development

(2010) J. Jack Lee et al.   Clinical Trials

Selecting Promising Treatments in Randomized Phase II Cancer Trials with an Active Control

(2009) Ying Kuen Cheung   Journal of Biopharmaceutical Statistics

Confirmatory adaptive designs with Bayesian decision tools for a targeted therapy in oncology

(2009) Werner Brannath et al.   STATISTICS IN MEDICINE

Multi-Arm Clinical Trials of New Agents: Some Design Considerations

(2008) B. Freidlin et al.   CLINICAL CANCER RESEARCH

Optimising the design of phase II oncology trials: The importance of randomisation

(2008) Mark J. Ratain et al.   EUROPEAN JOURNAL OF CANCER

Monitoring for Lack of Benefit: A Critical Component of a Randomized Clinical Trial

(2008) Boris Freidlin et al.   JOURNAL OF CLINICAL ONCOLOGY

Randomized phase II trials with a prospective control

(2007) Sin-Ho Jung   STATISTICS IN MEDICINE