SFRP1 is a possible candidate for epigenetic therapy in non-small cell lung cancer

Identification of aberrant gene expression associated with aberrant promoter methylation in primordial germ cells between E13 and E16 rat F3 generation vinclozolin lineage

(2015) Y-h Taguchi   BMC BIOINFORMATICS

Principal component analysis-based unsupervised feature extraction applied to in silico drug discovery for posttraumatic stress disorder-mediated heart disease

(2015) Y-h Taguchi et al.   BMC BIOINFORMATICS

Epigenetics in lung cancer diagnosis and therapy

(2015) Aditi Mehta et al.   CANCER AND METASTASIS REVIEWS

Epigenetic Silencing of SPINT2 Promotes Cancer Cell Motility via HGF-MET Pathway Activation in Melanoma

(2015) Soonyean Hwang et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Comprehensive analysis of transcriptome and metabolome analysis in Intrahepatic Cholangiocarcinoma and Hepatocellular Carcinoma

(2015) Yoshiki Murakami et al.   Scientific Reports

ZDOCK server: interactive docking prediction of protein-protein complexes and symmetric multimers

(2014) B. G. Pierce et al.   BIOINFORMATICS

TINAGL1 and B3GALNT1 are potential therapy target genes to suppress metastasis in non-small cell lung cancer

(2014) Hideaki Umeyama et al.   BMC GENOMICS

Genes associated with genotype-specific DNA methylation in squamous cell carcinoma as candidate drug targets

(2014) Ryoichi Kinoshita et al.   BMC Systems Biology

The BioGRID interaction database: 2015 update

(2014) Andrew Chatr-aryamontri et al.   NUCLEIC ACIDS RESEARCH

HMGA1 Interacts with β-Catenin to Positively Regulate Wnt/β-Catenin Signaling in Colorectal Cancer Cells

(2014) Junjie Xing et al.   PATHOLOGY & ONCOLOGY RESEARCH

Comparison of Hepatocellular Carcinoma miRNA Expression Profiling as Evaluated by Next Generation Sequencing and Microarray

(2014) Yoshiki Murakami et al.   PLoS One

Promoter Methylation-Mediated Silencing of β-Catenin Enhances Invasiveness of Non-Small Cell Lung Cancer and Predicts Adverse Prognosis

(2014) Yuan Miao et al.   PLoS One

Bioinformatic Screening of Autoimmune Disease Genes and Protein Structure Prediction with FAMS for Drug Discovery

(2014) Shigeharu Ishida et al.   PROTEIN AND PEPTIDE LETTERS

The relationship between DNA methylation, genetic and expression inter-individual variation in untransformed human fibroblasts

(2014) James R Wagner et al.   GENOME BIOLOGY

GROMACS 4.5: a high-throughput and highly parallel open source molecular simulation toolkit

(2013) Sander Pronk et al.   BIOINFORMATICS

Targeting transcription factor SALL4 in acute myeloid leukemia by interrupting its interaction with an epigenetic complex

(2013) C. Gao et al.   BLOOD

EGFR-TKI Resistance Due to BIM Polymorphism Can Be Circumvented in Combination with HDAC Inhibition

(2013) T. Nakagawa et al.   CANCER RESEARCH

EpCAM Is an Endoderm-Specific Wnt Derepressor that Licenses Hepatic Development

(2013) Huiqiang Lu et al.   DEVELOPMENTAL CELL

The transcription factor SALL4 regulates stemness of EpCAM-positive hepatocellular carcinoma

(2013) Sha Sha Zeng et al.   JOURNAL OF HEPATOLOGY

Wnt Signaling Pathway in Non-Small Cell Lung Cancer

(2013) D. J. Stewart   JNCI-Journal of the National Cancer Institute

Nuclear β-catenin accumulation is associated with increased expression of Nanog protein and predicts poor prognosis of non-small cell lung cancer

(2013) Xi-Qing Li et al.   Journal of Translational Medicine

Principal Component Analysis Based Feature Extraction Approach to Identify Circulating microRNA Biomarkers

(2013) Y-h. Taguchi et al.   PLoS One

A Hox gene controls lateral line cell migration by regulating chemokine receptor expression downstream of Wnt signaling

(2013) M. A. Breau et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Inhibition of androgen receptor and  -catenin activity in prostate cancer

(2013) E. Lee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

ALDH3A1 is overexpressed in a subset of hepatocellular carcinoma characterised by activation of the Wnt/ß-catenin pathway

(2013) Julien Calderaro et al.   VIRCHOWS ARCHIV

The HDAC inhibitor, MPT0E028, enhances erlotinib-induced cell death in EGFR-TKI-resistant NSCLC cells

(2013) M-C Chen et al.   Cell Death & Disease

Pre-Clinical Studies of Epigenetic Therapies Targeting Histone Modifiers in Lung Cancer

(2013) Kenneth Huffman et al.   Frontiers in Oncology

Epigenetic Therapy of Non-Small Cell Lung Cancer Using Decitabine (5-Aza-2′-Deoxycytidine)

(2013) Richard L. Momparler   Frontiers in Oncology

Targeting the Epigenome in Lung Cancer: Expanding Approaches to Epigenetic Therapy

(2013) Marko Jakopovic et al.   Frontiers in Oncology

Beta-catenin expression is prognostic of improved non–small cell lung cancer survival

(2012) Connie G. Chiu et al.   AMERICAN JOURNAL OF SURGERY

A Novel Function of YWHAZ/ -Catenin Axis in Promoting Epithelial-Mesenchymal Transition and Lung Cancer Metastasis

(2012) C.-H. Chen et al.   MOLECULAR CANCER RESEARCH

Reexpression of Tumor Suppressor, sFRP1, Leads to Antitumor Synergy of Combined HDAC and Methyltransferase Inhibitors in Chemoresistant Cancers

(2012) S. J. Cooper et al.   MOLECULAR CANCER THERAPEUTICS

Template-based protein structure modeling using the RaptorX web server

(2012) Morten Källberg et al.   Nature Protocols

Histone deacetylase inhibitors suppress mutant p53 transcription via histone deacetylase 8

(2012) W Yan et al.   ONCOGENE

Comprehensive miRNA Expression Analysis in Peripheral Blood Can Diagnose Liver Disease

(2012) Yoshiki Murakami et al.   PLoS One

Structural Basis of Wnt Recognition by Frizzled

(2012) C. Y. Janda et al.   SCIENCE

Reversal of Aberrant Cancer Methylome and Transcriptome upon Direct Reprogramming of Lung Cancer Cells

(2012) Dashayini Mahalingam et al.   Scientific Reports

Mest/Peg1 inhibits Wnt signalling through regulation of LRP6 glycosylation

(2011) Hwajin Jung et al.   BIOCHEMICAL JOURNAL

In silico modification of suberoylanilide hydroxamic acid (SAHA) as potential inhibitor for class II histone deacetylase (HDAC)

(2011) Usman SF Tambunan et al.   BMC BIOINFORMATICS

Methylation of multiple genes as a candidate biomarker in non-small cell lung cancer

(2011) Youwei Zhang et al.   CANCER LETTERS

Genome-Wide Analysis of Promoter Methylation Associated with Gene Expression Profile in Pancreatic Adenocarcinoma

(2011) A. Vincent et al.   CLINICAL CANCER RESEARCH

The L6 domain tetraspanin Tm4sf4 regulates endocrine pancreas differentiation and directed cell migration

(2011) K. R. Anderson et al.   DEVELOPMENT

Organosulfur derivatives of the HDAC inhibitor valproic acid sensitize human lung cancer cell lines to apoptosis and to cisplatin cytotoxicity

(2011) Anna Tesei et al.   JOURNAL OF CELLULAR PHYSIOLOGY

g:Profiler—a web server for functional interpretation of gene lists (2011 update)

(2011) Jüri Reimand et al.   NUCLEIC ACIDS RESEARCH

TargetMine, an Integrated Data Warehouse for Candidate Gene Prioritisation and Target Discovery

(2011) Yi-An Chen et al.   PLoS One

Loss of SFRP1 Expression is Associated with Aberrant β-Catenin Distribution and Tumor Progression in Mucoepidermoid Carcinoma of Salivary Glands

(2010) Chien-Hsing Lee et al.   ANNALS OF SURGICAL ONCOLOGY

Molecular analysis of gastric differentiated-type intramucosal and submucosal cancers

(2010) Tamotsu Sugai et al.   INTERNATIONAL JOURNAL OF CANCER

Aberrant expression of a  -catenin gain-of-function mutant induces hyperplastic transformation in the mouse cornea

(2010) Y. Zhang et al.   JOURNAL OF CELL SCIENCE

Transcriptional inactivation of secreted frizzled-related protein 1 by promoter hypermethylation as a potential biomarker for non-small cell lung cancer

(2010) Y. Zhang et al.   NEOPLASMA

FiberDock: a web server for flexible induced-fit backbone refinement in molecular docking

(2010) E. Mashiach et al.   NUCLEIC ACIDS RESEARCH

A Novel Histone Deacetylase Inhibitor Exhibits Antitumor Activity via Apoptosis Induction, F-Actin Disruption and Gene Acetylation in Lung Cancer

(2010) Yen-An Tang et al.   PLoS One

The Wnt antagonists Frzb-1 and Crescent locally regulate basement membrane dissolution in the developing primary mouth

(2009) A. J. G. Dickinson et al.   DEVELOPMENT

Laminin γ2 Mediates Wnt5a-Induced Invasion of Gastric Cancer Cells

(2009) Hideki Yamamoto et al.   GASTROENTEROLOGY

Gendoo: Functional profiling of gene and disease features using MeSH vocabulary

(2009) Takeru Nakazato et al.   NUCLEIC ACIDS RESEARCH

Stem Cell Factor SALL4 Represses the Transcriptions of PTEN and SALL1 through an Epigenetic Repressor Complex

(2009) Jiayun Lu et al.   PLoS One

Defining a Chromatin Pattern that Characterizes DNA-Hypermethylated Genes in Colon Cancer Cells

(2008) K. M. McGarvey et al.   CANCER RESEARCH

Epigenetic alteration of Wnt pathway antagonists in progressive glandular neoplasia of the lung

(2008) Julien D.F. Licchesi et al.   CARCINOGENESIS

Sfrp1, Sfrp2, and Sfrp5 regulate the Wnt/β-catenin and the planar cell polarity pathways during early trunk formation in mouse

(2008) Wataru Satoh et al.   GENESIS

Putative direct and indirect Wnt targets identified through consistent gene expression changes in APC-mutant intestinal adenomas from humans and mice

(2008) Stefania Segditsas et al.   HUMAN MOLECULAR GENETICS

Antitumor activity of histone deacetylase inhibitors in non-small cell lung cancer cells: development of a molecular predictive model

(2008) A. Miyanaga et al.   MOLECULAR CANCER THERAPEUTICS