DDX3 modulates cisplatin resistance in OSCC through ALKBH5-mediated m6A-demethylation of FOXM1 and NANOG

Inhibition of SIRT1 deacetylase and p53 activation uncouples the anti-inflammatory and chemopreventive actions of NSAIDs

(2019) Giulia Dell’Omo et al.   BRITISH JOURNAL OF CANCER

DDX3 activates CBC-eIF3-mediated translation of uORF-containing oncogenic mRNAs to promote metastasis in HNSCC

(2018) Hung-Hsi Chen et al.   CANCER RESEARCH

Potential Benefit of Intra-operative Administration of Ketorolac on Breast Cancer Recurrence According to the Patient’s Body Mass Index

(2018) Christine Desmedt et al.   JNCI-Journal of the National Cancer Institute

Potential Benefit of Intra-operative Administration of Ketorolac on Breast Cancer Recurrence According to the Patient’s Body Mass Index

(2018) Christine Desmedt et al.   JNCI-Journal of the National Cancer Institute

STAT3- and GSK3β-mediated Mcl-1 regulation modulates TPF resistance in oral squamous cell carcinoma

(2018) Santanu Maji et al.   CARCINOGENESIS

The RNA helicase DDX3X is an essential mediator of innate antimicrobial immunity

(2018) Daniel Szappanos et al.   PLoS Pathogens

FOXM1 recruits nuclear Aurora kinase A to participate in a positive feedback loop essential for the self-renewal of breast cancer stem cells

(2017) N Yang et al.   ONCOGENE

The DEAD-Box RNA Helicase DDX3 Interacts with m6A RNA Demethylase ALKBH5

(2017) Abdullah Shah et al.   Stem Cells International

Hypoxia induces the breast cancer stem cell phenotype by HIF-dependent and ALKBH5-mediated m6A-demethylation of NANOG mRNA

(2016) Chuanzhao Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

DDX3 promotes tumor invasion in colorectal cancer via the CK1ε/Dvl2 axis

(2016) Tsung-Ying He et al.   Scientific Reports

Targeting DDX3 with a small molecule inhibitor for lung cancer therapy

(2015) G. M. Bol et al.   EMBO Molecular Medicine

Mcl-1 is an important therapeutic target for oral squamous cell carcinomas

(2015) Santanu Maji et al.   Oncotarget

Ketorolac salt is a newly discovered DDX3 inhibitor to treat oral cancer

(2015) Sabindra K. Samal et al.   Scientific Reports

Intraoperative use of ketorolac or diclofenac is associated with improved disease-free survival and overall survival in conservative breast cancer surgery

(2014) P. Forget et al.   BRITISH JOURNAL OF ANAESTHESIA

Cancer incidence and mortality worldwide: Sources, methods and major patterns in GLOBOCAN 2012

(2014) Jacques Ferlay et al.   INTERNATIONAL JOURNAL OF CANCER

DDX3 modulates cell adhesion and motility and cancer cell metastasis via Rac1-mediated signaling pathway

(2014) H-H Chen et al.   ONCOGENE

Ketorolac Tromethamine - Routes and Clinical Implications

(2014) Nalini Vadivelu et al.   Pain Practice

Reduction of Breast Cancer Relapses with Perioperative Non-Steroidal Anti-Inflammatory Drugs: New Findings and a Review

(2013) Michael Retsky et al.   CURRENT MEDICINAL CHEMISTRY

Perioperative ketorolac in high risk breast cancer patients. Rationale, feasibility and methodology of a prospective randomized placebo-controlled trial

(2013) Patrice Forget et al.   MEDICAL HYPOTHESES

RNA Helicase DDX3 Is a Regulatory Subunit of Casein Kinase 1 in Wnt- -Catenin Signaling

(2013) C.-M. Cruciat et al.   SCIENCE

Oral cancer: Current role of radiotherapy and chemotherapy

(2013) SH. Huang et al.   Medicina Oral Patologia Oral y Cirugia Bucal

Topology of the human and mouse m6A RNA methylomes revealed by m6A-seq

(2012) Dan Dominissini et al.   NATURE

The DEAD-box helicase DDX3 supports the assembly of functional 80S ribosomes

(2012) Rene Geissler et al.   NUCLEIC ACIDS RESEARCH

Induction chemotherapy with cisplatin and fluorouracil alone or in combination with docetaxel in locally advanced squamous-cell cancer of the head and neck: long-term results of the TAX 324 randomised phase 3 trial

(2011) Jochen H Lorch et al.   LANCET ONCOLOGY

Expression of DDX3 Is Directly Modulated by Hypoxia Inducible Factor-1 Alpha in Breast Epithelial Cells

(2011) Mahendran Botlagunta et al.   PLoS One

Do Intraoperative Analgesics Influence Breast Cancer Recurrence After Mastectomy? A Retrospective Analysis

(2010) Patrice Forget et al.   ANESTHESIA AND ANALGESIA

NANOG regulates glioma stem cells and is essential in vivo acting in a cross-functional network with GLI1 and p53

(2010) Marie Zbinden et al.   EMBO JOURNAL

Oncogenic role of DDX3 in breast cancer biogenesis

(2008) M Botlagunta et al.   ONCOGENE