Esketamine: A Novel Option for Treatment-Resistant Depression

Single, Repeated, and Maintenance Ketamine Infusions for Treatment-Resistant Depression: A Randomized Controlled Trial

(2019) Jennifer L. Phillips et al.   AMERICAN JOURNAL OF PSYCHIATRY

Efficacy and Safety of Flexibly Dosed Esketamine Nasal Spray Combined With a Newly Initiated Oral Antidepressant in Treatment-Resistant Depression: A Randomized Double-Blind Active-Controlled Study

(2019) Vanina Popova et al.   AMERICAN JOURNAL OF PSYCHIATRY

Efficacy and Safety of Fixed-Dose Esketamine Nasal Spray Combined With a New Oral Antidepressant in Treatment-Resistant Depression: Results of a Randomized, Double-Blind, Active-Controlled Study (TRANSFORM-1)

(2019) Maggie Fedgchin et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

Efficacy of Esketamine Nasal Spray Plus Oral Antidepressant Treatment for Relapse Prevention in Patients With Treatment-Resistant Depression

(2019) Ella J. Daly et al.   JAMA Psychiatry

The Effect of a Single Dose of Intravenous Ketamine on Suicidal Ideation: A Systematic Review and Individual Participant Data Meta-Analysis

(2018) Samuel T. Wilkinson et al.   AMERICAN JOURNAL OF PSYCHIATRY

Efficacy and Safety of Intranasal Esketamine for the Rapid Reduction of Symptoms of Depression and Suicidality in Patients at Imminent Risk for Suicide: Results of a Double-Blind, Randomized, Placebo-Controlled Study

(2018) Carla M. Canuso et al.   AMERICAN JOURNAL OF PSYCHIATRY

Treatment resistant depression: A multi-scale, systems biology approach

(2018) Huda Akil et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Effect of intranasal esketamine on cognitive functioning in healthy participants: a randomized, double-blind, placebo-controlled study

(2018) Randall L. Morrison et al.   PSYCHOPHARMACOLOGY

Glutamatergic Modulators in Depression

(2018) Ioline D. Henter et al.   HARVARD REVIEW OF PSYCHIATRY

Efficacy and Safety of Intranasal Esketamine Adjunctive to Oral Antidepressant Therapy in Treatment-Resistant Depression

(2018) Ella J. Daly et al.   JAMA Psychiatry

Repeated oral ketamine for out-patient treatment of resistant depression: randomised, double-blind, placebo-controlled, proof-of-concept study

(2018) Yoav Domany et al.   BRITISH JOURNAL OF PSYCHIATRY

Ketamine for Depression, 4: In What Dose, at What Rate, by What Route, for How Long, and at What Frequency?

(2017) Chittaranjan Andrade   JOURNAL OF CLINICAL PSYCHIATRY

A Double-Blind, Randomized, Placebo-Controlled, Dose-Frequency Study of Intravenous Ketamine in Patients With Treatment-Resistant Depression

(2016) Jaskaran B. Singh et al.   AMERICAN JOURNAL OF PSYCHIATRY

Intravenous Esketamine in Adult Treatment-Resistant Depression: A Double-Blind, Double-Randomization, Placebo-Controlled Study

(2016) Jaskaran B. Singh et al.   BIOLOGICAL PSYCHIATRY

Canadian Network for Mood and Anxiety Treatments (CANMAT) 2016 Clinical Guidelines for the Management of Adults with Major Depressive Disorder

(2016) Sidney H. Kennedy et al.   CANADIAN JOURNAL OF PSYCHIATRY-REVUE CANADIENNE DE PSYCHIATRIE

Treatment-resistant depression: Definitions, review of the evidence, and algorithmic approach

(2013) Roger S. McIntyre et al.   JOURNAL OF AFFECTIVE DISORDERS

Rapid and Longer-Term Antidepressant Effects of Repeated Ketamine Infusions in Treatment-Resistant Major Depression

(2012) James W. Murrough et al.   BIOLOGICAL PSYCHIATRY