Journal
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
Volume 59, Issue 23, Pages 8860-8863Publisher
WILEY-V C H VERLAG GMBH
DOI: 10.1002/anie.201916111
Keywords
drug loading; nanotubes; peptide-polymer conjugates; photo-responsive materials; tubisomes
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Funding
- Royal Society Wolfson Merit Award [WM130055]
- European Research Council [TUSUPO647106]
- National Natural Science Foundation of China [21861130352]
- Newton Advanced Fellowships of The Royal Society [NAF\R1\180066]
- Marie Sklodowska-Curie action (TSPBNTM)
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Typically, the morphologies of the self-assembled nanostructures from block copolymers are limited to spherical micelles, wormlike micelles and vesicles. Now, a new generation of materials with unique shape and structures, cylindrical soft matter particles (tubisomes), are obtained from the hierarchical self-assembly of cyclic peptide-bridged amphiphilic diblock copolymers. The capacity of obtained photo-responsive tubisomes as potential drug carriers is evaluated. The supramolecular tubisomes pave an alternative way for fabricating polymeric tubular structures, and will expand the toolbox for the rational design of functional hierarchical nanostructures.
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