A Unified Total Synthesis of the Actinoallolides, a Family of Potent Anti-Trypanosomal Macrolides

Recent advances in ruthenium-based olefin metathesis

(2018) O. M. Ogba et al.   CHEMICAL SOCIETY REVIEWS

Identification and heterologous expression of the actinoallolide biosynthetic gene cluster

(2018) Yuki Inahashi et al.   JOURNAL OF ANTIBIOTICS

Chagas disease

(2018) José A Pérez-Molina et al.   LANCET

Natural products and ring-closing metathesis: synthesis of sterically congested olefins

(2018) C. Lecourt et al.   NATURAL PRODUCT REPORTS

Toward aplyronine payloads for antibody–drug conjugates: total synthesis of aplyronines A and D

(2018) Nika Anžiček et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Enantioselective, Protecting-Group-Free Total Synthesis of Boscartin F

(2018) Akinobu Matsuzawa et al.   ORGANIC LETTERS

Active Natural Product Scaffolds against Trypanosomatid Parasites: A Review

(2018) Peter E. Cockram et al.   JOURNAL OF NATURAL PRODUCTS

Toward the total synthesis of patellazole B: synthesis of an advanced C1–C25 fragment corresponding to the macrocyclic skeleton

(2018) Andrew W. Phillips et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Human African trypanosomiasis

(2017) Philippe Büscher et al.   LANCET

Anti-trypanosomatid drug discovery: an ongoing challenge and a continuing need

(2017) Mark C. Field et al.   NATURE REVIEWS MICROBIOLOGY

Current drug therapy and pharmaceutical challenges for Chagas disease

(2016) José Bermudez et al.   ACTA TROPICA

An Expedient Total Synthesis of Chivosazole F: an Actin-Binding Antimitotic Macrolide from the MyxobacteriumSorangium Cellulosum

(2016) Simon Williams et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Towards the total synthesis of the anti-trypanosomal macrolide, Actinoallolides: construction of a key linear intermediate

(2016) Jun Oshita et al.   TETRAHEDRON LETTERS

Chagas’ Disease

(2015) Caryn Bern   NEW ENGLAND JOURNAL OF MEDICINE

Actinoallolides A–E, New Anti-trypanosomal Macrolides, Produced by an Endophytic Actinomycete, Actinoallomurus fulvus MK10-036

(2015) Yuki Inahashi et al.   ORGANIC LETTERS

Total Synthesis and Structural Revision of Sekothrixide

(2014) Naoki Terayama et al.   ORGANIC LETTERS

Chagas Disease: “The New HIV/AIDS of the Americas”

(2012) Peter J. Hotez et al.   PLoS Neglected Tropical Diseases

Highly Stereoselective Synthesis of syn-1,3-Diols through a Sequential Titanium-Mediated Aldol Reaction and LiBH4 Reduction

(2010) Judit Esteve et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Human African trypanosomiasis

(2009) Reto Brun et al.   LANCET

Neglected Tropical Diseases in Sub-Saharan Africa: Review of Their Prevalence, Distribution, and Disease Burden

(2009) Peter J. Hotez et al.   PLoS Neglected Tropical Diseases