Article
Chemistry, Analytical
Xiang-yu Kong, Shao-Min Shuang, Yue-tao Zhang, Yu Wang, Chuan Dong
Summary: A novel fluorescence probe, YT, based on dicyanoisophorone, was synthesized for rapid and selective detection of hypochlorite ions. The probe showed a large Stokes shift and responded to hypochlorite ions by changing its fluorescence peak and color. It exhibited a good linear relationship within a certain concentration range.
Article
Chemistry, Physical
Hongxia Cui, Peng Hou, Yu Li, Jingwen Sun, Haiyan Zhang, Yan Zheng, Qi Liu, Song Chen
Summary: In this study, a novel ratiometric fluorescence probe PHPQ for detecting ClO- was designed and synthesized, showing selective and sensitive monitoring capabilities. It displayed significant fluorescence ratiometric variations and was successfully used for bioimaging exogenous/endogenous ClO- in living cells and in zebrafish.
JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY
(2021)
Article
Chemistry, Analytical
Xiaoqing Wang, Jingjing Zhang, Yijing Cui, Hong Wang, Wen Lu, Li Xu
Summary: This paper reports the design and preparation of a new fluorescent nanoprobe for ratiometric detection of ClO- within five seconds, with highly selective and sensitive response. The probe demonstrated excellent imaging performance in living cells and zebrafish larvae, showing potential application in ClO--related chemical biology studies.
MICROCHEMICAL JOURNAL
(2022)
Article
Chemistry, Analytical
Si-Lin Xu, Fang-Fang Guo, Zhi-Hong Xu, Yuan Wang, Tony D. James
Summary: A water-soluble fluorescent probe 1 based on chromene-hemicyanine has been developed, which exhibits colorimetric fluorescent response towards hypochlorite (ClO-) with a low LOD (0.082 mu M), and turn-on response to viscosity changes. Due to its low cytotoxicity and good biocompatibility, probe 1 is used to monitor hypochlorous acid and viscosity in mitochondria of living cells and zebrafish.
SENSORS AND ACTUATORS B-CHEMICAL
(2023)
Article
Biophysics
Lijuan Gui, Jun Yan, Junyuan Zhao, Shiya Wang, Yingying Ji, Ji Liu, Jinsheng Wu, Kang Yuan, Heng Liu, Dawei Deng, Zhenwei Yuan
Summary: This study developed a novel ratiometric probe Rx-NCE to detect hypochlorite levels in foam cells and outline the boundaries of atherosclerotic plaques. The innovative application of this probe in distinguishing atherosclerotic blood vessels is also demonstrated. This research has significant value in studying ER stress and atherosclerosis.
BIOSENSORS & BIOELECTRONICS
(2023)
Article
Biochemical Research Methods
Liangqiang Wu, Shaolong Qi, Yan Liu, Xinyu Wang, Lubao Zhu, Qingbiao Yang, Jianshi Du, Hai Xu, Yaoxian Li
Summary: The synthesized ratio fluorescent probe is capable of differential detection of hydrogen sulfite and hypochlorite, with high sensitivity and selectivity. It has advantages of larger Stokes shift, longer lambda(em), and better water solubility.
ANALYTICAL AND BIOANALYTICAL CHEMISTRY
(2021)
Article
Chemistry, Analytical
Zhoupeng Zheng, Shumin Feng, Shengyi Gong, Guoqiang Feng
Summary: Gol-CO is an effective fluorescence probe for imaging CO in Golgi apparatus, with high selectivity and sensitivity. It can target Golgi apparatus in living cells and zebrafish, and visualize the level increase of CO under oxidative stress.
SENSORS AND ACTUATORS B-CHEMICAL
(2021)
Article
Chemistry, Analytical
Xiao-Chuang Chang, Ling Zhang, Bing-Jie Liu, Yan-Tao Lou, Wei-Fan Xu, Xin-Ru Li, Xue-Feng Han, Wei-Na Wu, Yuan Wang, Zhi-Hong Xu
Summary: A novel pyrene-based fluorescent probe was synthesized for the detection of hypochlorite (ClO-) with aggregation-induced ratiometric emission (AIRE) at 525 nm in aqueous solution. The probe showed a fast and sensitive fluorescent response to ClO- within 20 seconds with a detection limit of 269 nM. The sensing mechanism of the probe was investigated using various techniques, and it was successfully applied for imaging endogenous and exogenous ClO- in living cells and zebrafish.
MICROCHEMICAL JOURNAL
(2023)
Article
Chemistry, Analytical
Wenjie Liang, Gang Nie, Jinjin Che, Zhengjiang Zhang, Dugang Chen, Wenbo Wu
Summary: There is a lack of effective and friendly diagnostic technique for alcoholic liver disease (ALD). Fluorescence imaging, which has been widely applied in disease diagnostic ascribed to the merits of high sensitivity, excellent temporal resolution and minimal invasiveness, is probably a good candidate for ALD studying.
SENSORS AND ACTUATORS B-CHEMICAL
(2023)
Article
Spectroscopy
Cheng-lu Zhang, Xiang-ling Li, Yan-hua Jiang, Yi-ning Zhang, Yan-xuan Xie, Yue-dong Sun, Cui Liu
Summary: A ratiometric fluorescent probe (NQ) based on FRET was designed and synthesized, which showed high sensitivity and selectivity in detecting ClO-. It had a fast response time and strong anti-interference effect. Moreover, NQ could be applied to detect ClO- in real water samples and living cell imaging.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2022)
Article
Chemistry, Applied
Lin Wang, Kang Niu, Shijun Chen, Yuanyuan Wu, Yangyou Tang, Shicong Hou, Wenxue Wu
Summary: In this study, a highly selective and sensitive near-infrared ratiometric fluorescent probe was developed for real-time monitoring of alkaline phosphatase activity. The probe exhibited the shortest response time, large Stokes shift, low cytotoxicity, and strong anti-interference ability.
Article
Spectroscopy
Jiaojiao Liu, Peixin Niu, Yifan Rong, Wenqiang Chen, Xingjiang Liu, Liuhe Wei, Xiangzhi Song
Summary: A lysosomal-targeted fluorescent probe Cou-Lyso was developed for real-time detection of ClO- in cells, showing high sensitivity and low detection limit. Confocal imaging experiments demonstrated that this probe could detect ClO- in living cells and zebra fish, providing a promising tool for studying ClO- in complex biological systems.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2021)
Article
Polymer Science
Shi-Lu Ji, Hua-Min Lan, Sen-Sen Zhou, Xiao-Ke Zhang, Wei-Zhi Chen, Xi-Qun Jiang
Summary: Two new ratiometric hypoxia probes (Ir-C343 and Ir-GFP) were synthesized by incorporating fluorescent internal standard molecules (coumarin 343 and green fluorescent protein) into a bis[1-(9,9-dimethyl-9H-fluoren-2-yl)-isoquinoline] succinylacetone Ir(III) (Ir-fliq). The probes exhibited a ratiometric response to oxygen concentration, as the fluorescence intensity of the internal standard remained constant while the Ir-fliq moiety remained sensitive to oxygen concentration. Ir-GFP showed promising potential in ratiometric hypoxia imaging due to its long excitation wavelength, water solubility, biocompatibility, and lower fluorescence intensity compared to Ir-fliq.
CHINESE JOURNAL OF POLYMER SCIENCE
(2023)
Article
Chemistry, Multidisciplinary
Xiaoxiao Hu, Hongjing Wu, Qiang Zhang, Feng Gao
Summary: Accurate and selective detection and imaging of intracellular L-lysine and pH in biological systems have been highly desired to serve as biomarkers for abnormal conditions and disease occurrence warnings. The design of new ratiometric fluorescent probe for monitoring L-lysine and pH has attracted more attention to improve detection accuracy. Carbonized polymer dots (CPDs), a new type of fluorescent nanomaterials, exhibit many advantages for bioanalysis. In this study, CPDs were synthesized through one-step hydrothermal amide method using o-phenylenediamine (o-PD) and poly(styrene-co-maleic anhydride) (PSMA) as the precursors. Ratiometric detection and imaging of L-lysine and pH were successfully achieved based on the different responsive behaviors of CPDs.
CHINESE CHEMICAL LETTERS
(2023)
Article
Chemistry, Physical
Xinrui Yang, Liying Jin, Yuheng Chen, Xiuli Zhong, Yuliang Jiang, Zhihui Dai
Summary: Monitoring hypochlorite levels at the organelle level is crucial for early disease diagnosis. A novel coumarin-based aggregation-induced emission probe (AIE-CDs) was developed for rapid and sensitive detection of hypochlorite, showing potential for biological applications through monitoring and imaging in living cells and zebrafish.
JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY
(2021)
Article
Oncology
J. Peng, H. J. Wu, H. F. Zhang, S. Q. Fang, R. Zeng
Summary: In HCC cells, FGF1 is highly expressed while miR-143-3p is poorly expressed. Both indicators have AUCs > 0.8 and are correlated with patient characteristics. Silencing FGF1 and overexpressing miR-143-3p promote cell apoptosis, inhibit cell growth, EMT, and affect the expression of related proteins. Targeted relationship between FGF1 and miR-143-3p is confirmed and inhibiting FGF1 may become a potential therapeutic target for HCC.
CLINICAL & TRANSLATIONAL ONCOLOGY
(2021)
Correction
Biochemistry & Molecular Biology
Ya-Xin Zhao, Jie-Fan Liu, Wei-Jian Sun, Rui-Feng Zeng, Ting Li, Rui-Min Ma
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2021)
Review
Medicine, General & Internal
Qinqin Wu, Fanghui Li, Yu Jia, Yi Liu, Rui Zeng
Summary: This study aims to compare the impact of different types of physical activity on the risk of sudden cardiac death through a systematic review and meta-analysis. The results will be disseminated through peer-reviewed publications, journals, academic conferences, and other forms of exchange.
Article
Engineering, Environmental
Jin-Shuai Lan, Rui-Feng Zeng, Yu Wang, Lu Zhen, Yun Liu, Rodney J. Y. Ho, Yue Ding, Tong Zhang
Summary: A fluorescent probe based on intramolecular charge transfer was developed for the detection of SO2 derivatives, allowing for accurate quantification, real-time monitoring, and bioimaging of SO32-/HSO3-.
JOURNAL OF HAZARDOUS MATERIALS
(2022)
Article
Oncology
Huai-yu Wang, Suyuan Peng, Zhanghui Ye, Pengfei Li, Qing Li, Xuanyu Shi, Rui Zeng, Ying Yao, Fan He, Junhua Li, Liu Liu, Shuwang Ge, Xianjun Ke, Zhibin Zhou, Gang Xu, Ming-hui Zhao, Haibo Wang, Luxia Zhang, Erdan Dong
Summary: The study found that the use of RAS-I and ARB in COVID-19 patients can reduce the risk of all-cause mortality, especially for patients with hypertension.
FRONTIERS OF MEDICINE
(2022)
Article
Polymer Science
Xinyi Luo, Kunlun Zhang, Ruiming Zeng, Ying Chen, Li Zhang, Jianbo Tan
Summary: A novel difunctional RAFT agent with an asymmetric structure was synthesized and used to prepare segmented macro-RAFT agents, leading to the formation of segmented copolymers with different blocks. Introduction of a certain number of trithiocarbonate groups on the surface of block copolymer nano-objects was achieved, providing a platform for further chain extension and functionalization. This study not only provides important mechanistic insights into RAFT polymerization mediated by multifunctional RAFT agents but also enables the preparation of functional block copolymer nano-objects.
Article
Chemistry, Medicinal
Guanlan Chen, Rui Zeng, Xin Wang, Hongying Cai, Jiajia Chen, Yingxiong Zhong, Saiyi Zhong, Xuejing Jia
Summary: Clam heparinoid G2 and its depolymerized derivatives DG1 and DG2 have shown excellent fibrinolytic and anticoagulant activity. Results indicate that G2 has a high anticoagulant effect, while DG2 has a greater thrombolytic activity. Furthermore, oral administration of DG1 reduces thrombus formation, increases tissue-type plasminogen activator levels, and improves changes in intestinal bacteria. These findings suggest that DG1 could be an oral agent with antithrombotic properties.
Article
Medicine, General & Internal
R. Zeng, H. Wu, X. Qiu, Z. Zhuo, W. Sha, H. Chen
Summary: This study developed an effective prognostic signature for predicting colorectal cancer (CRC) by evaluating the signal transducer and activator of transcription (STAT) signaling. The signature was significantly associated with CRC survival and correlated with the tumor immune microenvironment. The hub gene Caveolin-1 (CAV1) within the signature was found to inhibit cell proliferation, induce apoptosis and senescence, and suppress tumor angiogenesis in CRC. This research highlights the importance of the STAT regulator CAV1 and suggests that modulating STAT and its regulators could be a promising strategy for CRC in clinical practice.
QJM-AN INTERNATIONAL JOURNAL OF MEDICINE
(2022)
Article
Biochemistry & Molecular Biology
Barbara Santos, Rui Zeng, Sasa F. Jorge, Jose Ribamar Ferreira-Junior, Antoni Barrientos, Mario H. Barros
Summary: Mitoribosomes in Saccharomyces cerevisiae consist of a 54S large subunit and a 37S small subunit, containing a total of 73 mitoribosome proteins and two ribosomal RNAs. These proteins have adapted by acquiring new proteins, extensions, and RNA segments, to synthesize highly hydrophobic membrane proteins. The study investigates the functional relevance of mitochondria-specific protein extensions in the mtLSU, revealing their importance in mitochondrial protein synthesis capacities and rRNAs interactions.
Article
Biotechnology & Applied Microbiology
Rui-Jie Zeng, Wei-Jie Xie, Chun-Wen Zheng, Wan-Xian Chen, Si-Meng Wang, Zheng Li, Chi-Bin Cheng, Hai-Ying Zou, Li-Yan Xu, En-Min Li
Summary: The downregulation of Rho guanine nucleotide exchange factors (GEFs) ABR, PREX1, DOCK2 and DOCK4 in non-small cell lung cancer (NSCLC) tissues is associated with poor prognosis, potentially due to promoter methylation. ABR, in particular, has been identified as a tumor suppressor in NSCLC, offering new avenues for researchers to explore the distinct roles of Rho GEFs in cancer pathogenesis.
Review
Multidisciplinary Sciences
Ruijie Zeng, Zewei Zhuo, Yujun Luo, Weihong Sha, Hao Chen
Summary: Rho GTPases play crucial roles in the pathogenesis of various rheumatic diseases, promoting disease progression through activation of downstream pathways. Therapeutic strategies using Rho GTPase inhibitors have shown promising effects in the treatment of rheumatic diseases. Future studies should focus on further exploring the role of Rho GTPases in rheumatic diseases based on current understandings.
Article
Environmental Sciences
Tianfang Xu, Qianqiu Longyang, Conor Tyson, Ruijie Zeng, Bethany T. Neilson
Summary: This study presents a hybrid modeling approach that combines a physically based snow model with a deep learning karst model to predict streamflow in mountainous karst watersheds. The approach is tested on a watershed in northern Utah and shows high accuracy in simulating streamflow. The deep learning model captures the spatiotemporal recharge and discharge patterns and provides valuable insights into hydrologic responses influenced by complex surface and subsurface properties.
WATER RESOURCES RESEARCH
(2022)
Review
Medicine, General & Internal
Chujin Cao, Han Zhu, Ying Yao, Rui Zeng
Summary: Gut dysbiosis is a major mechanism in the development of kidney diseases, and improving the gut microbiota can potentially slow down the progression of kidney diseases.
FRONTIERS IN MEDICINE
(2022)
Proceedings Paper
Computer Science, Interdisciplinary Applications
Zixin Peng, Genglin Zhu, Mu Li, Ruifeng Zeng, Sibo Cheng, Kaisheng Wang
Summary: This paper investigates how to balance the safety and cost-effectiveness of UAVs in fighting forest fires. Through a case study, the particle swarm algorithm, topology spanning tree algorithm, and ant colony algorithm are used to optimize the patrol paths and minimize the cost of the drones.
2ND INTERNATIONAL CONFERENCE ON APPLIED MATHEMATICS, MODELLING, AND INTELLIGENT COMPUTING (CAMMIC 2022)
(2022)
Article
Medicine, General & Internal
Chen Zhang, Yunjiu Cheng, Dongling Luo, Jinghua Wang, Jianhua Liu, Yujun Luo, Weijie Zhou, Zewei Zhuo, Kehang Guo, Ruijie Zeng, Jun Yang, Weihong Sha, Hao Chen
Summary: The study revealed that unfavorable cardiovascular risk factors are associated with an increased risk of colorectal cancer.
Article
Chemistry, Analytical
Yujia Ying, Huilin Li
Summary: Enzymes play a crucial role as biological catalysts in accelerating biochemical reactions in living organisms. This study proposes a convenient method for monitoring enzymatic catalytic processes using native top-down mass spectrometry. By exploring the heterogeneity of the chymotrypsin sample and using tandem mass spectrometry, the researchers were able to monitor covalent and noncovalent enzymatic complexes, substrates, and products during catalysis. The results demonstrate that this method has the potential to be a promising tool for characterizing biocatalysts.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Kang Yang, Shuaibo Shi, Jinyu Wu, Shaolong Han, Shengdi Tai, Shishen Zhang, Kun Zhang
Summary: H2O and D2O are important analogues closely related to various industries and monitoring fields. This study successfully distinguishes and detects H2O and D2O by designing a novel eu(III)-macrocycle with dual emitters, Eu-2a, and conducting fluorescence titration experiments.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Julia Kuligowski, Alvaro Perez-Rubio, Marta Moreno-Torres, Polina Soluyanova, Judith Perez-Rojas, Ivan Rienda, David Perez-Guaita, Eugenia Pareja, Ramon Trullenque-Juan, Jose Castell, Marcha Verheijen, Florian Caiment, Ramiro Jover, Guillermo Quintas
Summary: This study introduces a novel variable selection approach called cluster PLS (c-PLS) to assess the joint impact of variable groups selected based on biological characteristics on the predictive performance of a multivariate model. The usefulness of c-PLS is shown using miRNomic and metabolomic datasets obtained from the analysis of liver tissue biopsies.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Meixue Lai, Lijie Zhong, Siyi Liu, Yitian Tang, Tingting Han, Huali Deng, Yu Bao, Yingming Ma, Wei Wang, Li Niu, Shiyu Gan
Summary: This study presents a method for constructing wearable sweat electrolyte sensors using carbon fiber-based solid-contact ion-selective electrodes (SC-ISEs). By using carbon fibers extracted from commercial cloth as electrode material, the cost and reproducibility issues of flexible SC-ISEs were addressed. The results showed that the carbon fiber-based SC-ISEs exhibited reversible voltammetric and stable impedance performances, and had high reproducibility of standard potentials between normal and bending states.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Ke Yang, Ying Liu, Min Deng, Peipei Wang, Dan Cheng, Songjiao Li, Longwei He
Summary: A near-infrared fluorescent probe has been developed to accurately measure the levels of peroxynitrite (ONOO-) in the endoplasmic reticulum (ER) in acute lung injury (ALI). The probe demonstrated rapid response, high selectivity, good sensitivity, and enhanced fluorescence intensity in response to ONOO-. It was successfully used to detect changes in ONOO- levels and showed significant increases in an ALI cell model and an ALI mouse model.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Yanping Wang, Yuemei Chen, Kejun Li, Jinrong Zhou, Xin Yuan, Mei Zhang, Ke Huang
Summary: In this work, a portable analytical system based on point discharge chemical vapor generation atomic emission spectrometry (PD-CVG-AES) coupling with gold filament enrichment was designed. The highly sensitive analysis of Hg2+ indirectly realized the detection of ascorbic acid (AA). The measurement is based on the fact that Ag+ can decrease the concentration of Hg2+ by forming Ag-Hg amalgam in the presence of the reductant SnCl2, while AA can pre-reduce Ag+ to Ag0, leading to the generation of silver nanoparticles (Ag NPs). The developed novel analytical strategy broadens the application of microplasma-based AES and offers a higher level of sensitivity compared to current AA detection techniques.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Yundi Huang, Bo Song, Kaiwen Chen, Deshu Kong, Jingli Yuan
Summary: This study developed two lysosome-targetable background-free TGL probes for efficient and accurate detection of 1O2, which can be used for monitoring endogenous 1O2 concentrations in lysosomes and discriminating variability induced by different photosensitizers. Furthermore, a smart luminescent sensor film was successfully prepared for on-site 1O2 production detection during PDT processes, offering a promising clinical monitoring tool for skin diseases.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Wei Lang, Jia-Mei Qin, Qian-Yong Cao
Summary: A novel polymer-based probe P1 was successfully synthesized for fluorescently ratiometric sensing of H2S with high selectivity and sensitivity. A smartphone sensing platform was constructed to conduct visual quantitative detection of H2S. P1 can be employed in evaluating the level fluctuations of H2S in living cells, testing water samples/wine samples, and monitoring food freshness.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Yuanyuan Qin, Shuda Liu, Shuyun Meng, Dong Liu, Tianyan You
Summary: The study developed a split aptamer-based sandwich-type ratiometric biosensor for the detection of 17 beta-estradiol (E2) using photoelectrochemical and electrochemical assays. The biosensor utilized split aptamer fragments to recognize E2 and trigger a hybridization chain reaction, resulting in the production of double-stranded DNA labeled with CdTe quantum dots. This DNA complex was able to sensitize CdTe quantum dots and generate response signals for E2 detection. The developed biosensor demonstrated high sensitivity and accuracy with two linear ranges and low detection limits.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Siriwan Teepoo, Jongjit Jantra, Khaunnapa Panapong, David Taiwo Ajayi
Summary: A novel immunochromatographic assay based on hyperbranched Au plasmonic blackbodies with a smartphone readout was developed for rapid and sensitive detection of leucomalachite green residues in fish and shrimp products.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Andrea L. Larraga-Urdaz, Borja Moreira-Alvarez, Jorge Ruiz Encinar, Jose M. Costa-Fernandez, Maria Luisa Fernandez-Sanchez
Summary: A major challenge in the 21st century is the development of point-of-care diagnostic tools. In this study, a highly sensitive and simple bioassay using AuNPs and MNAzymes was developed for rapid detection and quantification of miRNA-4739. The proposed strategy shows potential for breast cancer diagnosis.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Xiaohan Zhao, Anyu Wang, Lingzi Zhai, Jiuhe Gao, Sizhe Lyu, Yingshan Jiang, Tian Zhong, Ying Xiao, Xi Yu
Summary: A novel method using polystyrene-coated magnetic nanoparticles for extracting monohydroxy polycyclic aromatic hydrocarbons from urine samples was investigated. The proposed method is simple, sensitive, and efficient, with desirable sensitivity for analyzing low-abundance metabolites in large volumes of complex urine samples.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Ke Quan, Yuqing Zeng, Wenke Zhang, Fengfeng Li, Mengjiao Li, Zhihe Qing, Linlin Wu
Summary: In this study, a visual and reusable biosensor was developed for detecting substrates that are closely associated with human physiological health. The immobilized oxidase showed higher stability and sensitivity under harsh conditions, enabling reliable detection of substrates in complex fluids.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Dongjuan Wang, Xiuqian Ding, Jinling Xie, Juan Wang, Guanhao Li, Xin Zhou
Summary: In this study, a three-in-one sensor was developed for real-time detection of biogenic amines (BAs) with high sensitivity and selectivity. The sensor showed multimodal responses and could be used to fabricate portable devices for on-site non-destructive assessment of food spoilage indicators.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Jinting Meng, Zihao Xu, Shasha Zheng, Hongqun Yang, Tianfu Wang, Hong Wang, Yingwei Zhang
Summary: This study demonstrates the development of a cascade signal amplification system using a multi-pedal DNA walker and strand displacement reactions for the electrochemical detection of miRNA-155. The biosensor exhibited high sensitivity, selectivity, and the potential for clinical applications.
ANALYTICA CHIMICA ACTA
(2024)
